Korean J Otorhinolaryngol-Head Neck Surg.  2013 Jan;56(1):14-18. 10.3342/kjorl-hns.2013.56.1.14.

Botox Therapy for Deep Nasolabial Fold and Bitterness Furrow after Facial Nerve Paralysis

• Noh SH
• Choi KH
• Lee JM
• Jeon JH
• Park SY
• Kim J

• KMID: 1426535
• DOI: http://doi.org/10.3342/kjorl-hns.2013.56.1.14

Abstract

BACKGROUND AND OBJECTIVES
Facial sequelae after facial paralysis cause serious functional and aesthetical problems including facial asymmetry, symkinesis and facial crease. The most common aesthetical problem is facial furrow and crease induced by facial hyperkinestic movement due to incomplete facial recovery. The aim of this study is to investigate the efficacy of botulinum toxin A injection in patients with deep nasolabial fold and bitterness furrow after facial paralysis.
SUBJECTS AND METHOD
Thirty-five patients who recovered partially from facial paralysis, had deep nasolabial fold and bitterness furrow with or without facial asymmetry. Botulinum toxin A intramuscular injection on perioral area for mouth corner deviation, subcutaneous injection on deepen nasolabial fold, and intramuscular injection on bitterness furrows had improved lower facial symmetry and cosmetic configuration without Pseudo Bell's palsy.
RESULTS
Of 26 patients who had facial palsy side nasolabial fold before the injection, 21 patients improved. Of the 21 patients who had facial palsy side bitterness furrow, 16 patients improved after the injection. Of 11 patients who had contralateral nasolabial fold, 4 patients improved after the injection. Of 13 patients who had contralateral bitterness furrow, 7 patients improved after the injection.
CONCLUSION
After botulinum toxin A injection, the patients showed marked improvement of nasolabial fold, bitterness furrow and lower facial asymmetry.

Keyword

Bitterness furrow; Botulinum toxin A; Facial palsy; Nasolabial fold

MeSH Terms

Botulinum Toxins
Botulinum Toxins, Type A
Cosmetics
Facial Asymmetry
Facial Nerve
Facial Paralysis
Humans
Injections, Intramuscular
Injections, Subcutaneous
Mouth
Nasolabial Fold
Paralysis
Botulinum Toxins
Botulinum Toxins, Type A
Cosmetics