Korean J Radiol.  2012 Aug;13(4):505-509. 10.3348/kjr.2012.13.4.505.

Acute Severe Thrombocytopenia Following Non-Ionic Low-Osmolarity Intravenous Contrast Medium Injection

• Bata P
• Tarnoki AD
• Tarnoki DL
• Horvath E
• Berczi V
• Szalay F

• KMID: 1383865
• DOI: http://doi.org/10.3348/kjr.2012.13.4.505

Abstract

Intravenous contrast medium (ICM) rarely induces anaphylactic reactions, including urticaria, hypotension and respiratory failure. Even the most modern ICM may cause such adverse events. Thrombocytopenia has been reported as an extreme rare consequence of ICM. Here we report on a case of a 72-year-old male patient with a self-limiting severe acute thrombocytopenia following administration of intravenous non-ionic low-osmolarity contrast medium. No such low platelet count has ever been reported. We also present a review of the literature.

Keyword

Intravenous contrast material; Thrombocytopenia; Immunoallergic mechanism

MeSH Terms

Aged
Comorbidity
Contrast Media/*administration & dosage/*adverse effects/chemistry
Diagnosis, Differential
Humans
Injections, Intravenous
Kidney Diseases/radiography
Male
Osmolar Concentration
Thrombocytopenia/*chemically induced
Tomography, X-Ray Computed
Triiodobenzoic Acids/*administration & dosage/*adverse effects/chemistry

Figure

• 

  Fig. 1 Platelet (PLT) level before and after development of acute severe thrombocytopenia. It should be noted that time scale is non-proportional; it refers to Dates studied.

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