Korean J Nephrol.
2006 Sep;25(5):823-827.
A Case of Collagenofibrotic Glomerulopathy with Characteristic Electron Microscopic and Immunohistochemistry Findings
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. yousukim@snu.ac.kr
- 2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
- Collagenofibrotic glomerulopathy is a relatively rare glomerular disease characterized by the accumulation of spiraled frayed collagen fibrils in mesangial and subendothelial areas. Clinically, patients with the disease usually present with moderate proteinuria and edema. They tend to have hypertension and their renal function deteriorates slowly. We report the case of a patient with collagenofibrotic glomerulopathy who also had Takayasus arteritis and presented with hypertension, proteinuria and dyspnea on exertion. Electron microscopy of the renal biopsy revealed massive accumulation of peculiar collagen fibers and immunohistology using monoclonal antibodies to collagen type III revealed positive stain in glomerular tufts.
MeSH Terms
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Pathogenesis of Transplant Glomerulopathy
- Pathology of C3 Glomerulopathy
- Pathology of Glomerulonephritis: Specimen Preparation and Basic Pathologic Changes
- Membranous Glomerulopathy Showing Asymptomatic Isolated Microscopic Hematuria Only
- A Case of Podocytic Infolding Glomerulopathy in an Allograft Kidney
