Korean J Gastroenterol.  2003 Feb;41(2):145-149.

Intramural Hematoma of the Small Intestine in a Patient with Hemophilia A

  • 1Department of Gastroenterology, Eulji University School of Medicine, Seoul, Korea. pys1109@eulji.or.kr
  • 2Department of Radiology, Eulji University School of Medicine, Seoul, Korea.


Hemophilia A is a severe bleeding disorder resulting from the lack of functional blood coagulation factor VIII. Clinically the disease is characterized by frequent spontaneous bleeding into the weight bearing joints, soft tissue and muscle. Intramural gastrointestinal hemorrhage develops as a recognized complication of trauma, anticoagulant therapy, and bleeding diatheses. Spontaneous intramural hemorrhage of the small intestine is uncommon even in patients with hemophilia. A 51-year-old man presented with abdominal pain for 5 days without trauma history. On admission, his plain abdominal X-ray showed gaseous distension of the proximal small bowel loops. An abdominal CT scan and small bowel barium study revealed multisegmental wall thickening and luminal narrowing at the proximal portion of the small bowel. He was improved after adminstration of clotting factor VIII and antibiotics. We report this case with a review of literature.


Hemophilia A; Intramural hematoma; Intestinal obstruction

MeSH Terms

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