J Korean Med Sci.  2007 Aug;22(4):762-765. 10.3346/jkms.2007.22.4.762.

Syringocystadenocarcinoma Papilliferum: A Case Report

Affiliations
  • 1Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. dhshin@med.yu.ac.kr

Abstract

Syringocystadenocarcinoma papilliferum (SCACP) is a rare form of adenocarcinoma of the skin. This is the malignant counterpart of syringocystadenoma papilliferum (SCAP) and usually develops on the scalp in a long-standing lesion identified clinically as SCAP. We describe a 65-yr-old Korean man with a nodule on the right supra-pubic area with a 2-yr duration. Histologically this tumor had a similar overall configuration as in SCAP, but the tumor was asymmetric and poorly circumscribed, extending into the deep dermis and showed cytologic atypia. The tumor cells showed positive reaction to GCDFP-15, but negative reaction to CEA and HMFG-1. We established the diagnosis of SCACP in the patient, and a wide excision was performed to remove the tumor. The patient has been well without relapse or metastasis for 2 yr.

Keyword

Sweat Gland Neoplasm; Apocrine Gland; Carcinoma

MeSH Terms

Aged
Carrier Proteins/analysis
Cystadenocarcinoma, Papillary/metabolism/*pathology
Glycoproteins/analysis
Humans
Immunohistochemistry
Male
Sweat Gland Neoplasms/metabolism/*pathology
Syringoma/metabolism/*pathology
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