Korean J Radiol.  2011 Jun;12(3):400-401. 10.3348/kjr.2011.12.3.400.

RE: Role of Duplex Doppler US for Thyroid Nodules: Looking for the "Sword" Sign

Affiliations
  • 1Department of Radiology, Centre d'imagerie Medicale, Centre Medico Chirurgical (CMC), France. lacout.alexis@wanadoo.fr
  • 2Head & Neck and Interventional Radiology, Department Antoine Lacassagne Cancer Research Institute, France.
  • 3Department of Radiation Oncology, Antoine Lacassagne Cancer Research Institute, France.

Abstract

Duplex Doppler US may be useful for the detection of thyroid malignancies that show either anarchic winding or penetrating "sword like" neoangiogenic vessels. It may be helpful in selecting nodules that should undergo fine needle aspiration biopsy.

Keyword

Doppler US; Ultrasonography; Anaplastic carcinoma; Thyroid

MeSH Terms

Biopsy, Fine-Needle
Diagnosis, Differential
Humans
Thyroid Neoplasms/blood supply/pathology/*ultrasonography
Thyroid Nodule/blood supply/pathology/*ultrasonography
*Ultrasonography, Doppler, Duplex
Ultrasonography, Interventional

Figure

  • Fig. 1 Patient who presented with poorly-differentiated papillary thyroid carcinoma. Doppler US shows large vessel (arrows) crossing from side-to-side in suspicious left hypoechoic thyroid nodule (arrowhead), as sword would do ("sword sign"). Fine-needle aspiration biopsy confirmed high grade malignancy of this aggressive nodule.


Reference

1. Algin O, Algin E, Gokalp G, Ocakoglu G, Erdogan C, Saraydaroglu O, et al. Role of duplex power Doppler ultrasound in differentiation between malignant and benign thyroid nodules. Korean J Radiol. 2010. 11:594–602.
2. Cibas ES, Alexander EK, Benson CB, de Agustin PP, Doherty GM, Faquin WC, et al. Indications for thyroid FNA and pre-FNA requirements: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference. Diagn Cytopathol. 2008. 36:390–399.
3. Lyshchik A, Moses R, Barnes SL, Higashi T, Asato R, Miga MI, et al. Quantitative analysis of tumor vascularity in benign and malignant solid thyroid nodules. J Ultrasound Med. 2007. 26:837–846.
4. Spiezia S, Colao A, Assanti AP, Cerbone G, Picone GM, Merola B, et al. Usefulness of color echo Doppler with power Doppler in the diagnosis of hypoechoic thyroid nodules: work in progress. Radiol Med. 1996. 91:616–621.
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