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Usage Patterns and Incidence of Thyroid-related Adverse Events in Patients Treated with PD-1 Inhibitors

Hwang S, Kim H, Chung S, Min M, Suh DC

Objective: PD-1 inhibitors have demonstrated improved health outcomes in cancer patients. PD-1 inhibitors are well-tolerated and associated with immune-related adverse events. The objectives of this study are to analyze use...
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Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis

Lee J, Cho Y, Choi KH, Hwang I, Oh YL

Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple...
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Proto-oncogene Pokemon in thyroid cancer: a potential promoter of tumorigenesis in papillary thyroid carcinoma

Chang K, Do SI, Kim K, Chae SW, Do Ig, Lee HJ, Kim DH, Sohn JH

Background: Pokemon is an oncogenic transcription regulator that plays a critical role in cellular differentiation. Although it has been found to be overexpressed in several types of cancer involving different...
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Shock Thyroid in a Patient with Septic Shock: A Case Report and Literature Review

Kim WH, Kim MS, Kim JH, Lee KH, Lee JH

Shock thyroid is a rare manifestation of the CT hypotension complex and can be diagnosed when thyroid and perithyroidal edemas are observed on CT during the onset of shock. Shock...
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The Relationship Between Night Shift Work and the Risk of Abnormal Thyroid-Stimulating Hormone: A Hospital-Based Nine-Year Follow-up Retrospective Cohort Study in Taiwan

Chen HH, Chiu HH, Yeh TL, Lin CM, Huang HY, Wu SL

Background Health-care providers typically undergo shift work and are subjected to increased stress. Night shift work may induce disturbed sleep cycles and circadian rhythm. The objective of this study was to...
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Diagnostic Performance of the Modified Korean Thyroid Imaging Reporting and Data System for Thyroid Malignancy: A Multicenter Validation Study

Chung SR, Ahn HS, Choi YJ, Lee JY, Yoo RE, Lee YJ, Kim JY, Sung JY, Kim Jh, Baek JH

Objective: To evaluate the diagnostic performance of the modified Korean Thyroid Imaging Reporting and Data System (K-TIRADS), and compare it with the 2016 version of K-TIRADS using the Thyroid Imaging...
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Korean Thyroid Imaging Reporting and Data System: Current Status, Challenges, and Future Perspectives

Ha EJ, Na DG, Baek JH

The Korean Thyroid Imaging Reporting and Data System (K-TIRADS) is an ultrasound-based risk stratification system for thyroid nodules that has been widely applied for the diagnosis and management of thyroid...
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Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo

Lin CL, Tsai ML, Chen Yh, Liu WN, Lin CY, Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH

Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as...
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A Case of Occult Anaplastic Thyroid Cancer Presenting as Huge Renal Mass

Lee JH, Yang Y, Lee EJ

Anaplastic thyroid cancers (ATC) are a rapid growing and highly lethal form of thyroid cancer. Distant metastases of ATC are detected in about half of patients. Clinically, it is very...
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Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients

Ahn J, Lee MK, Lee JH, Sohn SY

Background: Data on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, including overt thyrotoxicosis and suppression of thyroid function. We aimed to evaluate the thyroid hormone...
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Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones

Kim BH, Joo Y, Kim MS, Choe HK, Tong Q, Kwon O

Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels,...
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The Concept of Economic Evaluation and Its Application in Thyroid Cancer Research

Kim K, Kim M, Lim W, Kim BH, Park SK

Economic evaluation is a type of comparative analysis between interventions in terms of both their resource use and health outcomes. Due to the good prognosis of thyroid cancer (TC), the...
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COVID-19 Vaccination for Endocrine Patients: A Position Statement from the Korean Endocrine Society

Ku CR, Jung KY, Ahn CH, Moon JS, Lee JH, Kim EH, Kwon H, Kim HK, Suh S, Hong S, Ha J, Roh E, Kim JH, Kim Mk, the Committee of Clinical Practice Guideline of the Korean Endocrine Society

Since the first outbreak of coronavirus disease 2019 (COVID-19), ongoing efforts have been made to discover an efficacious vaccine against COVID-19 to combat the pandemic. In most countries, both mRNA...
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The Effect of Levator Recession for Upper Eyelid Retraction in Patients with Thyroid-associated Ophthalmopathy

Oh JY, Lee JK

Purpose: We analyzed factors that affect the outcome of levator recession surgery for upper eyelid retraction in patients with thyroid-associated ophthalmopathy. Methods: Retrospective analysis was performed based on the medical records...
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Association between Iodine Intake, Thyroid Function, and Papillary Thyroid Cancer: A Case-Control Study

Kim K, Cho SW, Park YJ, Lee KE, Lee DW, Park SK

Background: This study aimed to assess the effects of iodine intake, thyroid function, and their combined effect on the risk of papillary thyroid cancer (PTC) and papillary thyroid microcarcinoma (PTMC). Methods:...
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Active Surveillance as an Effective Management Option for Low-Risk Papillary Thyroid Microcarcinoma

Jeon MJ, Kim WG, Kim TY, Shong YK, Kim WB

Active surveillance (AS) for low-risk papillary thyroid microcarcinoma (PTMC) has been accepted worldwide as safe and effective. Despite the growing acceptance of AS in the management of low-risk PTMCs, there...
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The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65

Wang X, Wang H, Yan L, Yang L, Xue Y, Yang J, Yao Y, Tang X, Tong N, Wang G, Zhang J, Wang Y, Ba J, Chen B, Du J, He L, Lai X, Li Y, Yan Z, Liao E, Liu C, Liu L, Qin G, Qin Y, Quan H, Shi B, Sun H, Ye Z, Zhang Q, Zhang L, Zhu J, Zhu M, Li Y, Teng W, Shan Z

Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of the study was to analyze the association...
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The Role of Thyroid Hormone in the Regulation of Cerebellar Development

Ishii S, Amano I, Koibuchi N

The proper organized expression of specific genes in time and space is responsible for the organogenesis of the central nervous system including the cerebellum. The epigenetic regulation of gene expression...
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The Role of Tc-99 m-MIBI Scan in the Assessment of the Cystic Thyroid Nodule

Hurtado-López LM, Martínez-Duncker C

Purpose A non-surgical therapeutic option requires assurance that a cystic thyroid nodule with non-diagnostic cytology is benign. This work was undertaken to determine whether Tc-99 m-MIBI scan (MIBI) findings can guide...
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Radiofrequency Ablation of Papillary Thyroid Microcarcinoma: A 10-Year Follow-Up Study

Seo YK, Cho SW, Sim JS, Yang GE, Cho W

Purpose To investigate the efficacy and safety of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) after > 10 years of follow-up. Materials and Methods This study included five patients who...
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