J Vet Sci.  2011 Jun;12(2):165-169. 10.4142/jvs.2011.12.2.165.

White spots on the mucosal surface of the duodenum in dogs with lymphocytic plasmacytic enteritis

• Garcia-Sancho M
• Sainz A
• Villaescusa A
• Rodriguez
• Rodriguez-Franco F

• KMID: 1106559
• DOI: http://doi.org/10.4142/jvs.2011.12.2.165

Abstract

Distended lacteals, described as expanded white villi in duodenum, are strongly indicative of primary intestinal lymphangiectasia. In the present study, we evaluated the significance of white spots present in the duodenal mucosa of dogs with lymphocytic plasmacytic enteritis (LPE). Fifty dogs with LPE were included in this study, and white spots were detected in the duodenal mucosa in 22 dogs during endoscopy. Hypoproteinemia was more frequent in dogs with white spots than in dogs without spots (p = 0.02). Serum protein and albumin concentration were significantly lower in LPE dogs with white spots (p = 0.038) compared to LPE dogs without white spots (p = 0.039). There was a significant correlation between white spots density and lymphatic dilatation histological scores (p = 0.023; rho = 0.481). These results suggest that the presence of white spots in the duodenal mucosa of dogs is not a finding exclusive for intestinal lymphangiectasia. Low serum protein and albumin concentrations together with lymphatic dilatation seem to be related to the presence of white spots in the duodenal mucosa of LPE dogs.

Keyword

canine; endoscopy; inflammatory bowel disease; intestinal lymphangiectasia

MeSH Terms

Animals
Biopsy/veterinary
Blood Proteins/metabolism
Dog Diseases/blood/*pathology
Dogs
Duodenum/*pathology
Endoscopy/veterinary
Female
Histocytochemistry/veterinary
Intestinal Mucosa/*pathology
Lymphangiectasis, Intestinal/blood/pathology/*veterinary
Male
Retrospective Studies
Statistics, Nonparametric