J Yeungnam Med Sci.  2022 Jan;39(1):72-76. 10.12701/yujm.2021.01067.

Enteritis cystica profunda with lipoma in the second portion of the duodenum: a case report

• Shim BJ
• Park SK
• Park HU
• Park TY

• KMID: 2525032
• DOI: http://doi.org/10.12701/yujm.2021.01067

Abstract

Enteritis cystica profunda (ECP), a rare and benign condition, is defined as the displacement of the glandular epithelium into the submucosa and more profound layers of the small intestinal wall leading to the formation of mucin-filled cystic spaces. ECP frequently occurs in the ileum or jejunum and is associated with diseases such as Crohn disease and Peutz-Jeghers syndrome. ECP also develops in the absence of known pathology. ECP in the duodenum is very rare and mostly occurs without associated conditions. In this report, we present a rare case of ECP without an associated disease, in the second portion of the duodenum distal to the ampulla of Vater and coexisting with lipoma within the polypoid lesion.

Keyword

Duodenum; Enteritis cystica profunda; Lipoma

Figure

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  Fig. 1. Esophagogastroduodenoscopy findings. The elongated polyp is in the second portion of the duodenum distal to the ampulla of Vater and covered with normal surrounding mucosa. There are erosions (arrows) on the head of the polyp.

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  Fig. 2. Abdominal computed tomography (CT) findings. Axial CT image shows a focal fat-density mass (arrow) in the second portion of the duodenum, which indicates lipoma.

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  Fig. 3. Endoscopic polypectomy. The polyp is captured by a hemoclip and detachable snare and then resected by the snare.

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  Fig. 4. Gross findings. The polyp measures about 3.5×1.5×1.0 cm.

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  Fig. 5. Histological findings. The coexistence of cystically dilated mucosal glands and mature adipocytes is present in the submucosa (hematoxylin and eosin stain, ×40).

Reference

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