Korean J Ophthalmol.  2005 Mar;19(1):40-46. 10.3341/kjo.2005.19.1.40.

Comparison of Glaucomatous Parameters in Normal, Ocular Hypertensive and Glaucomatous Eyes Using Optical Coherence Tomography 3000

• Choi MG
• Han M
• Kim YI
• Lee JH

• KMID: 1099084
• DOI: http://doi.org/10.3341/kjo.2005.19.1.40

Abstract

This study was performed to evaluate optic disc appearance, retinal nerve fiber layer (RNFL) thickness, and macular thickness in normal, ocular hypertensive (OHT) and glaucomatous eyes using optical coherence tomography (OCT) 3000. One hundred fifty-eight eyes of 167 consecutive subjects were enrolled: 60 normal, 53 OHT, and 54 glaucomatous. OCT topographic parameters of cup diameter, cup area, rim area, and cup/disc area ratio were significantly less in OHT eyes than in normal eyes and were significantly less in glaucomatous eyes than in normal and OHT eyes. RNFL was significantly thinner in OHT eyes than in normal eyes in the inferior quadrant, and in glaucomatous eyes than in OHT and normal eyes in the mean and for all four quadrants. Macular thickness was significantly thinner in glaucomatous eyes than in OHT and normal eyes throughout all subdivisions. Optic disc parameters, and RNFL and macular thickness measurements made with OCT may be useful in the clinical assessment of glaucoma.

Keyword

Macular thickness; Optical coherence tomography; Optic disc parameter; Retinal nerve fiber layer thickness

MeSH Terms

Adult
Comparative Study
Female
Glaucoma/*diagnosis
Humans
Male
Middle Aged
Nerve Fibers/*pathology
Ocular Hypertension/diagnosis
Optic Disk/*pathology
Optic Nerve Diseases/*diagnosis
Research Support, Non-U.S. Gov't
Retinal Ganglion Cells/*pathology
Tomography, Optical Coherence/*methods

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