J Korean Med Sci.  2003 Dec;18(6):917-920. 10.3346/jkms.2003.18.6.917.

Idiopathic Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease in a Young Male Patient: A Case Report

• Ahn JK
• Kim HJ
• Kim EH
• Jeon CH
• Cha HS
• Ha CW
• Ahn JM
• Koh EM

• KMID: 1086757
• DOI: http://doi.org/10.3346/jkms.2003.18.6.917

Abstract

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is a disease of the elderly and extremely rare in young individuals. If young people develop CPPD crystal deposition disease, it may be associated with metabolic diseases such as hemochromatosis, hyperparathyroidism, hypophosphatasia, hypomagnesemia, Wilson's disease, hypothyroidism, gout, acromegaly, and X-linked hypophosphatemic rickets. Therefore, in young-onset polyarticular CPPD crystal deposition disease, investigation for predisposing metabolic conditions is warranted. We report a case of a young male patient with idiopathic CPPD crystal deposition disease, who did not have any evidences of metabolic diseases after thorough evaluations. As far as we know, this is the first report of a young male patient presented with idiopathic CPPD crystal deposition disease.

Keyword

Calcium Pyrophosphate; Chondrocalcinosis; Idiopathic Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease; Young Male

MeSH Terms

Adult
Calcium Pyrophosphate/*metabolism
Cartilage, Articular/metabolism/pathology
Diagnosis, Differential
Human
Knee Joint/*pathology
Male
Metabolic Diseases/metabolism/pathology
Shoulder Joint/pathology