Korean J Hepatol.  2011 Jun;17(2):87-95. 10.3350/kjhep.2011.17.2.87.

Epidemiology and prevention of hepatitis B virus infection

Affiliations
  • 1Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. chlee@kuh.ac.kr

Abstract

Hepatitis B virus (HBV) infection has been a major global cause of morbidity and mortality. The recognition of the problem led to a worldwide effort to reduce transmission of HBV through routine infant vaccination. HBV infection is the most common cause of chronic liver diseases and hepatocellular carcinoma in Korea. After hepatitis B vaccine era, seroprevalence of hepatits B surface antigen is decreasing, particularly in children. Hepatitis B vaccine is remarkably safe and shows high immunogenicity. Universal childhood immunization with three doses of hepatitis B vaccine in the first year of life is a highly effective method for prevention and control of hepatitis B.

Keyword

Hepatitis B virus; Epidemiology; Vaccine; Prevention
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