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A Unique Cause of Mitral Regurgitation–Mitral Commissural Prolapse

Yaacob NF, Shariff RER, Yusoff MR, Ibrahim KS, Kasim S

A 65-year-old female patient was referred following worsening failure symptoms. Transthoracic echocardiography (TTE) demonstrated a prolapsed posterior leaflet of the mitral valve (MV). However, there was a widely spreading mitral...
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Factors Associated With Risk of Suicide Among Out-of-School Youths

Jo J, Kim J, Bae H, Chon MW, Lee KS, Lee SH

Objectives This study examined the factors associated with suicide risk among out-of-school youths (OSY) by analyzing their medical records retrospectively. Methods The medical records of 280 OSYs who were admitted to...
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A Clinical Observation on Tuberculous Meningitis in Childhood

1. Age and sex distribution: 90.9% were under the age of 6, the greatest number being between the age of 1 and 2. Male to female was 1. 75: 1. 2....
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Evaluation of the efficacy and safety of conversion from the tacrolimus capsule to tablet in stable liver transplant recipients with maintenance therapy: a 24-week, open-label, single-center, phase IV exploratory clinical study

Kim JY, Chang S, Kim J, Choi HH, Lee J, Hong Sy, Lee JM, Hong SK, Choi Y, Yi NJ, Lee KW, Suh KS

Purpose: The tablet form of tacrolimus is more convenient for drug ingestion than the capsule form. We examined the efficacy and safety of tacrolimus tablets and a satisfaction survey after...
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Mucosal Immunity Related to CD8+ T Lymphocytes in Children with Helicobacter pylori Gastritis

Yang DH, Lee HY, Choi W, Hyun CL, Kang KS

Purpose: We investigated the role of CD8+ T cells as host immune factors in pediatric patients with Helicobacter pylori gastritis. Methods: Gastric mucosal tissue and blood samples were collected from 39...
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Surgical outcomes of laparoscopic donor hepatectomy performed by fellowship-trained surgeons: a comparative study with the expert surgeon

Cho CW, Choi Gs, Kim KS

Background: Implementation of laparoscopic donor hepatectomy (LDH) is still limited to the experienced surgeons. In 2019, Seoul guideline recommends that LDH should be performed by surgeons with expertise in open...
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Push-out bond strength and intratubular biomineralization of a hydraulic root-end filling material premixed with dimethyl sulfoxide as a vehicle

Park JH, Kim HJ, Lee KW, Yu MK, Min KS

Objectives: This study was designed to evaluate the parameters of bonding performance to root dentin, including push-out bond strength and dentinal tubular biomineralization, of a hydraulic bioceramic root-end filling material...
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Aqueous extract of Laurus nobilis leaf accelerates the alcohol metabolism and prevents liver damage in singleethanol binge rats

Jung JI, Choi YJ, Kim J, Baek KS, Kim EJ

BACKGROUND/OBJECTIVES: Excessive alcohol consumption has harmful health effects, including alcohol hangovers and alcohol-related liver disease. Therefore, methods to accelerate the alcohol metabolism are needed. Laurus nobilis is a spice, flavoring...
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Relationship between Serum Ferritin Levels and Asymptomatic Hyperuricemia in Adult Males: Using Data from Medical Examinations of One University Hospital Health Examination Center (2020)

Kang SJ, Oh JE, Cho YJ, Shin HS, Yoo BW, Hong SH, Joe H, Son DY, Shin KS

Background: Serum ferritin levels can be used as an auxiliary indicator of inflammation. In addition, gout is an inflammatory disease whose risk increases with increasing uric acid levels. This study...
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Effect of desensitization protocol according to the degree of antibody-mediated rejection risk in living donor liver transplant: a retrospective cohort study

Kim J, Kim S, Jung M, Park JH, Yi Nj, Lee Jm, Hong SK, Lee KW, Suh KS, Choi Y

Background: Graft failure associated with donor specific antibody (DSA) is rare but consistent in living donor liver transplant (LDLT). This study aims to analyze the outcomes of desensitization protocol according...
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Noninferiority Outcomes of Besifovir Compared to Tenofovir Alafenamide in Treatment-Naïve Patients with Chronic Hepatitis B

Kim TH, Kim JH, Yim HJ, Seo YS, Yim SY, Lee YS, Jung YK, Yeon JE, Um SH, Byun KS

Background/Aims: Besifovir dipivoxil maleate (BSV) and tenofovir alafenamide fumarate (TAF) have been recently approved in Korea as the initial antiviral agents for chronic hepatitis B (CHB). However, the real-world outcome data...
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Rehabilitation after Repair of Medial Meniscus Posterior Root Tears: A Systematic Review of the Literature

Kim JS, Lee MK, Choi MY, Kong DH, Ha JK, Kim JG, Chung KS

Background: There is no consensus established on postoperative rehabilitation after medial meniscus posterior root tear (MMPRT) repair, including when and how physicians can apply range of motion (ROM) exercise, weight-bearing...
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Risk Factors Associated with Medication Adherence in HIV/AIDS Patients

Oh KS, Lee Js, Han E

Background: Adherence to antiretroviral treatment (ART) is crucial for maintaining the HIV-RNA suppression in patients living with HIV/AIDS. This study aims to analyze the risk factors contributing to low medication...
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Impact of peripheral blood mononuclear cells preconditioned by activated platelet supernatant in managing gastric mucosal damage induced by zinc oxide nanoparticles in rats

Badran D, El-Agroudy AEB, Kassab AA, El-Bayoumi KS, Eldken ZH, Elswaidy NRM

The world has witnessed tremendous advancements in nano-base applications. Zinc oxide nanoparticles (ZON) are widely used in food industry and medicine. Although their application is of important value, they may...
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The safety and feasibility of adjuvant immunotherapy with autologous cytokine-induced killer cells for patients with hepatocellular carcinoma beyond Milan criteria after liver transplantation

Hong G, Yang J, Suh KS, Kim JM, Lee KW, Yi NJ

Background: Adjuvant immunotherapy with autologous cytokine-induced killer (CIK) cells has shown promise postsurgery, yet research concerning hepatocellular carcinoma (HCC) patients postliver transplantation remains sparse. This scarcity is in part due...
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Therapeutic Outcomes and Electrophysiological Biomarkers in Anti-Myelin-Associated Glycoprotein Neuropathy: A Multicenter Cohort Study in South Korea

Min YG, Han HJ, Shin HY, Baek JG, Kim JS, Park KS, Baek SH, Yoo I, Huh SY, Kwon YN, Choi SJ, Kim SM, Hong YH, Sung JJ

Background and Purpose Unlike other immune-mediated neuropathies, anti-myelin-associated glycoprotein (MAG) neuropathy is often refractory to immunotherapy. It is necessary to compare the relative efficacies of various immunotherapies and develop objective...
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When is LABA/LAMA Better than LAMA in GOLD Group B or D Patients for Reducing Acute Exacerbations of COPD?

Shin HJ, Kim YI, Kim Y, Lee CY, Ra SW, Moon JY, Jung KS, Yoo KH, Shin KC, Lim SC, KOCOSS Cohort Study Group

Long-acting  2 -agonist (LABA)/long-acting muscarinic-antagonist (LAMA) dual therapy has been found to be more effective than LAMA monotherapy in the treatment of chronic obstructive pulmonary disease (COPD). However, among...
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Phosphodiesterase-5 Inhibitor Use in Robot Assisted Radical Prostatectomy Patients Is Associated with Reduced Risk of Death: A Propensity Score Matched Analysis of 1,058 Patients

Lee J, Kim HR, Heo JE, Jang WS, Lee KS, Kang SK, Han H, Choi YD

Purpose We investigated whether the use of a phosphodiesterase-5 inhibitor (PDE5i) after robot assited radical prostatectomy has a survival benefit over non-use patients because there are controversial results on the association...
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Increased risk of infections, renal dysfunction, and de novo malignancy in elderly liver transplant recipients on tacrolimus based immunosuppressive therapy: a propensity score-matched study from a single center

Kim MJ, Lee JY, Yi NJ, Choi Y, Lee KW, Suh KS, Kim AJ, Jo YH, Cho YS

Background: With the aging population, the number of organ transplants in elderly patients is on the rise. However, it is crucial to recognize that elderly patients often experience age-related decline...
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Factors affecting the long-term graft survival after pig to NHP renal xenotransplantation

Yun IJ, Hwang SA, Park KS, Min SI, Park JH, Kim WS, Choi WS

Background: The xenotransplantation research team at Konkuk University performed 30 pig-to-non-human primate (HNP) renal xenotransplantation since 2011. Among them, 12 NHPs showed survival from 30 to 80 days and five...
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