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Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk

Shrestha S, Hong CW

Neutrophils are professional phagocytes that provide defense against invading pathogens through phagocytosis, degranulation, generation of ROS, and the formation of neutrophil extracellular traps (NETs). Although long been considered as short-lived...
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Case Report: Erythema Multiforme Induced by Lithium Contact

Kim JC, Kang SY, Chung BY, Park CW, Kim HO

Erythema multiforme (EM) is an acute, self-limited mucocutaneous disease with diverse triggering factors, and the recurrences are quite common. A 24-year old male presented with multiple erythematous, itchy papules and...
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Diversity of Nigrospora (Xylariales, Apiosporaceae) Species Identified in Korean Macroalgae Including Five Unrecorded Species

Lee W, Kim DG, Perera RH, Kim JS, Cho Y, Lee JW, Seo CW, Lim YW

Nigrospora (Xylariales, Apiosporaceae) consists of species of terrestrial plant endophytes and pathogens. Nigrospora has also been reported in marine environments such as mangroves, sea fans, and macroalgae. However, limited research...
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Comparing ChatGPT’s ability to rate the degree of stereotypes and the consistency of stereotype attribution with those of medical students in New Zealand in developing a similarity rating test: a methodological study

Lin CC, Akuhata-Huntington Z, Hsu CW

Learning about one’s implicit bias is crucial for improving one’s cultural competency and thereby reducing health inequity. To evaluate bias among medical students following a previously developed cultural training program...
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Case Report of Erdheim-Chester Disease Successfully Treated with Pegylated Interferon: A Single-Center Experience

Lim Y, Yoon SE, Cho J, Kim D, Jung CW

Erdheim-Chester disease (ECD), also known as non-Langerhans cell histiocytosis, is a multi-systemic disease with unclear pathogenesis. Based on a small number of case studies, pegylated interferon-α (PEG-IFN-α) has been used...
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Long-term clinical outcomes of late conversion to once-daily tacrolimus and sirolimus combination in stable kidney transplant recipients

Oh YJ, Jung CW, Jun H, Kim MG, Park JH

Background: The use of calcineurin inhibitors (CNIs) has significantly improved graft outcomes in kidney transplantation (KT); however, nephrotoxicity resulting from their prolonged use presents a significant clinical concern that must...
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Usefulness of Direct Peroral Cholangioscopy Using a Multibending Ultraslim Endoscope for the Management of Intrahepatic Bile Duct Lesions (with Videos)

Lee WM, Moon JH, Lee YN, Min CW, Shin IS, Myeong JH, Kim HK, Yang JK, Lee TH

Background/Aims: Peroral cholangioscopy (POC) has been used to assess intrahepatic duct (IHD) lesions but with a limited role. A new multibending (MB) ultraslim endoscope has been designed to improve POC...
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Pre- and posttransplant BK virus-specific ELISPOT assay for predicting the outcome of BK virus infection in kidney transplant recip

Na D, Bae H, Lee H, Ko EJ, Yang CW, Chung BH, Oh EJ

Background: It is needed to plan optimal therapeutic strategies for controlling BK viremia. Our previous study showed that BK virus (BKV)-specific T cell immunity measured by an interferon enzyme-linked immunospot...
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Surgical outcomes of laparoscopic donor hepatectomy performed by fellowship-trained surgeons: a comparative study with the expert surgeon

Cho CW, Choi Gs, Kim KS

Background: Implementation of laparoscopic donor hepatectomy (LDH) is still limited to the experienced surgeons. In 2019, Seoul guideline recommends that LDH should be performed by surgeons with expertise in open...
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Impact of probiotic supplementation on kidney transplantation outcomes: a retrospective study

Jang Y, Kim Mg, Koo TY, Jun H, Jung CW, Oh YJ

Background: The impact of probiotic supplementation in kidney transplantation (KT) recipients on immunosuppressants has not been extensively studies, resulting in limited evidence regarding its effects. As a result, the potential...
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Modeling of allograft rejection using human induced pluripotent stem cell-derived kidney organoid system

Lim SW, Fang X, Cui S, Shin YJ, Lee H, Yang CW, Chung BH

Background: Kidney organoid derived human induced pluripotent stem cell (hiPSC) has been extensively studies as an alterna-tive cellular model for recapitulating phenotypic and pathophysiologic characters of human disease. In this...
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Bioactive Bone Substitute in a Rabbit Ulna Model: Preclinical Study

Hong YR, Kim TH, Lee K, Lim JO, Oh CW

BACKGROUND: Current therapies to effectively treat long-bone defects and extensive bone tissue loss remains limited. In this study, we created a new bone substitute by integrating advanced technologies such as structure...
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Aortic Annulus Detection Based on Deep Learning for Transcatheter Aortic Valve Replacement Using Cardiac Computed Tomography

Cho Y, Park S, Hwang SH, Ko M, Lim DS, Yu CW, Park SM, Kim MN, Oh YW, Yang G

Background: To propose a deep learning architecture for automatically detecting the complex structure of the aortic annulus plane using cardiac computed tomography (CT) for transcatheter aortic valve replacement (TAVR). Methods: This...
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Long-Term Efficacy and Safety of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria and High Disease Burden: Real-World Data From Korea

Kim JS, Jang JH, Jo DY, Ahn SY, Yoon SS, Lee JH, Kim SH, Choi CW, Shin HJ, Kim MK, Lee JH, Mun YC, Kong JH, Hyun B, Nam H, Kim E, Kwak MJ, Won YK, Lee JW

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder characterized by uncontrolled terminal complement activation. Eculizumab, a monoclonal antibody C5 inhibitor was introduced in Korea in 2009 and has...
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Transradial Versus Transfemoral Access for Bifurcation Percutaneous Coronary Intervention Using SecondGeneration Drug-Eluting Stent

Lee JH, Youn YJ, Jeon HS, Lee JW, Ahn SG, Yoon J, Gwon HC, Song YB, Choi KH, Kim HS, Chun WJ, Hur SH, Nam CW, Cho YK, Han SH, Rha SW, Chae IH, Jeong JO, Heo JH, Lim DS, Park JS, Hong MK, Doh JH, Cha KS, Kim DI, Lee SY, Chang K, Hwang BH, Choi SY, Jeong MH, Lee HJ

Background: The benefits of transradial access (TRA) over transfemoral access (TFA) for bifurcation percutaneous coronary intervention (PCI) are uncertain because of the limited availability of device selection. This study aimed...
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