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New oral anticoagulants

Oh S

The most important and widely-prescribed drug for anticoagulation is a vitamin K antagonist such as warfarin although it has several limitations in clinical use. New oral anticoagulants (NOACs) have been...
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The Effects of Taurine and ??-alanine on Blood Glucose and Blood Lipid Concentrations in Insulin-treated Diabetic Rats

Chang KJ

  • KMID: 2300794
  • Korean J Community Nutr.
  • 1999 Mar;4(1):103-110.
The purpose of this study was to determine the effects oftaurine supplementation and taurine depletion on blood glucose and blood lipid concentrations in insulin-treated diabetic rats. Four groups of Sprague-Dawley...
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Effect of intrathecal glycine and related amino acids on the allodynia and hyperalgesic action of strychnine or bicuculline in mice

Lim ES, Lee IO

BACKGROUND: The intrathecal (IT) administration of glycine or GABAA receptor antagonist result in a touch evoked allodynia through disinhibition in the spinal cord. Glycine is an inhibitory neurotransmitter that appears...
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Stroke Update 2011: New Antithrombotics

Seo KD, Lee KY

  • KMID: 2288709
  • Korean J Stroke.
  • 2012 Aug;14(2):62-66.
Several new antithrombotic drugs have been developed and approved to use in clinical practice recently. Dabigatran, a direct thrombin inhibitor, and rivaroxaban, a factor Xa inhibitor, have been approved in...
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Effects of carnosine and related compounds on monosaccharide autoxidation and H2O2 formation

Lee BJ, Kang KS, Nam SY, Park JH, Lee YS, Yun YW, Cho MH

  • KMID: 2285219
  • Korean J Physiol Pharmacol.
  • 1999 Jun;3(3):251-261.
The effects of carnosine and related compounds (CRCs) including anserine, homocarnosine, histidine, and beta-alanine on monosaccharide autoxidation and H2O2 formation were investigated. The incubation of CRCs with D-glucose, D-glucosamine, and D, L-glyceraldehyde at 37degreeC...
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Long-Term Anticoagulation in the Extreme Elderly with the Newer Antithrombotics: Safe or Sorry?

Chiong JR, Cheung RJ

BACKGROUND AND OBJECTIVES: The prevalence of atrial fibrillation (AF) doubles in the extreme elderly and is higher than in the rest of the population. Warfarin therapy to prevent thromboembolic events...
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Focused Update on Primary Stroke Prevention in Patients with Atrial Fibrillation in Korean Clinical Practice Guidelines for Stroke

Park JM, Hong KS, Han SW, Kim HY, Cho YJ, Kang K, Yu KH, Rha JH, Heo JH, Kwon SU, Oh CW, Bae HJ, Lee BC, Yoon BW, Koo J

  • KMID: 2288694
  • Korean J Stroke.
  • 2012 Dec;14(3):106-115.
Pivotal clinical trials testing the efficacy of new antithrombotics for the prevention of stroke and systemic embolism in patients with atrial fibrillation have been published since the release of the...
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