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NUP210 and MicroRNA-22 Modulate Fasto Elicit HeLa Cell Cycle Arrest

Gu Q, Hou W, Liu H, Shi L, Zhu Z, Ye W, Ni X

Purpose: Cervical cancer is one of the most fatal diseases among women in under-developed countries. To improve cervical cancer treatment, discovery of new targets is needed. In this study, we investigated...
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Excessive Startle with Novel GLRA1 Mutations in 4 Chinese Patients and a Literature Review of GLRA1-Related Hyperekplexia

Zhan F, Zhang C, Wang S, Zhu Z, Chen G, Zhao M, Cao L

Background and Purpose Hyperekplexia (HPX), a rare neurogenetic disorder, is classically characterized by neonatal hypertonia, exaggerated startle response provoked by the sudden external stimuli and followed by a shortly general stiffness....
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Molecular phylogenetic studies on clinical bovine piroplasmosis caused by benign Theileria in Shaanxi Province, China

Wang J, Zhang J, Zhu Z, Zhou X, Li B

A group of benign Theileria species, which are often referred to as T. orientalis/T. buffeli/T. sergenti group, has low pathogenicity in cattle. Herein, we report on Theileria spp. in cattle...
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Evaluation of Neck Lymph Node Metastasis on Contrast-Enhanced Ultrasound: An Animal Study

Cui Z, Gao Y, Wang W, Zhu Z, Zhang Y, Ma Z

OBJECTIVES: To assess the performance of contrast-enhanced ultrasound (CEUS) intended to differentiate hyperplastic from malignant neck lymph nodes in an animal model. METHODS: Twenty-four New Zealand rabbits were randomly divided into...
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Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model

Zhang YD, Zhu ZS, Zhang D, Zhang Z, Ma B, Zhao SC, Xue F

This study aimed to investigate the effect of Patched-1 (PTC1) and PTC2 silencing in a rat model, on Hedgehog (Hh) pathway-mediated recovery from spinal cord injury (SCI). An analytical emphasis...
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Helmet CPAP versus Oxygen Therapy in Hypoxemic Acute Respiratory Failure: A Meta-Analysis of Randomized Controlled Trials

Luo Y, Luo Y, Li Y, Zhou L, Zhu Z, Chen Y, Huang Y, Chen X

PURPOSE: The efficacy of helmet continuous positive airway pressure (CPAP) in hypoxemic acute respiratory failure (hARF) remains unclear. The aim of this meta-analysis was to critically review studies that investigated...
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Transcatheter Arterial Chemoembolization Plus ¹³¹I-Labelled Metuximab versus Transcatheter Arterial Chemoembolization Alone in Intermediate/Advanced Stage Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

Zhu ZX, Liao MH, Wang XX, Huang JW

OBJECTIVE: The aim of the study was to compare transcatheter arterial chemoembolization (TACE) plus ¹³¹I-labelled metuximab with TACE alone for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: A comprehensive search was conducted...
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Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis

Zhu Z, Xie Y, Guan W, Gao Y, Xia S, Shi X, Zheng J

BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine...
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Establishment and evaluation of a murine alphavbeta3-integrin-expressing cell line with increased susceptibility to Foot-and-mouth disease virus

Zhang W, Lian K, Yang F, Yang Y, Zhu Z, Zhu Z, Cao W, Mao R, Jin Y, He J, Guo J, Liu X, Zheng H

Integrin alphavbeta3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and roles of alphavbeta3 integrin, a stable CHO-677 cell line expressing...
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Sensitivity of Plasmodium falciparum to Antimalarial Drugs in Hainan Island, China

Wang SQ, Wang GZ, Li YC, Meng F, Lin SG, Zhu ZH, Sun DW, He CH, Hu XM, Du JW

Pyronaridine and artesunate have been shown to be effective in falciparum malaria treatment. However, pyronaridine is rarely used in Hainan Island clinically, and artesunate is not widely used as a...
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Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report

Zhu ZY, Chu ZG, Chen Y, Zhang WP, Lv D, Geng N, Yang MZ

  • KMID: 2277489
  • Korean J Pathol.
  • 2012 Oct;46(5):478-482.
Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously...
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A Modified Extraction Method of Circulating Free DNA for Epidermal Growth Factor Receptor Mutation Analysis

Yuan H, Zhu ZZ, Lu Y, Liu F, Zhang W, Huang G, Zhu G, Jiang B

PURPOSE: Circulating free DNA (cfDNA) in plasma is promising to be a surrogate for tumor tissue DNA. However, not all epidermal growth factor receptor (EGFR) mutations in tumor tissue DNA...
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Transient Receptor Potential Vanilloid Type-1 Channel in Cardiometabolic Protection

Wang P, Liu D, Zhu Z

Transient receptor potential vanilloid type-1 channel (TRPV1) is a non-selective cation channel with a preference for calcium ions that is able to sense a vast range of endogenous physical and...
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The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma

Zheng T, Yu J, Oh MH, Zhu Z

Atopic dermatitis (AD) is an inflammatory disease characterized by pruritic skin lesions. The pathogenesis of AD may include disrupted epidermal barrier function, immunodysregulation, and IgE-mediated sensitization to food and environmental...
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Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-gamma

Lee BJ, Moon HG, Shin TS, Jeon SG, Lee EY, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK

Recent clinical evidence indicates that the non-eosinophilic subtype of severe asthma is characterized by fixed airway obstruction, which may be related to emphysema. Transgenic studies have demonstrated that high levels...
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IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream...
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Myopericytoma Involving the Parotid Gland as Depicted on Multidetector CT

Chu ZG, Yu JQ, Yang ZG, Zhu ZY, Yuan HM

Myopericytoma is a newly proposed subgroup of perivascular tumors in the World Health Organization classification of soft tissue tumors. In this study, we report a case of a benign myopericytoma...
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Study on the Social Adaptation of Chinese Children with Down Syndrome

Wang YX, Mao SS, Xie CH, Qin YF, Zhu ZW, Zhan JY, Shao J, Li R, Zhao ZY

PURPOSE: To evaluate social adjustment and related factors among Chinese children with Down syndrome (DS). PATIENTS AND METHODS: A structured interview and Peabody Picture Vocabulary Test (PPVT) were conducted with...
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