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Genetic variants of interferon lambda-related genes and chronic kidney disease susceptibility in the Korean population

Kwak JH, Paek JH, Yu GI, Han S, Park WY, Kim Y, Shin DH, Jin K

Background: Chronic kidney disease (CKD) is a common condition leading to renal dysfunction and is closely related to increased cardiovascular and mortality risk. CKD is an important public health issue,...
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Epicardial Fat Thickness and Neutrophil to Lymphocyte Ratio are Increased in Non-Dipper Hypertensive Patients

Kim BJ, Cho KI, Choi JH, Park DH, Yu GI, Im SI, Kim HS, Heo JH, Cha TJ

BACKGROUND: In this study, we aimed to investigate the relationship between echocardiographic epicardial fat thickness (EFT), neutrophil to lymphocyte ratio (NLR; an important inflammatory marker), and diurnal blood pressure (BP)...
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Association between Interferon-Inducible Protein 6 (IFI6) Polymorphisms and Hepatitis B Virus Clearance

Park GH, Kim KY, Cho SW, Cheong JY, Yu GI, Shin DH, Kwack KB

CD8+ T cells are key factors mediating hepatitis B virus (HBV) clearance. However, these cells are killed through HBV-induced apoptosis during the antigen-presenting period in HBV-induced chronic liver disease (CLD)...
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Effect of Uric Acid on the Development of Chronic Kidney Disease: The Korean Multi-Rural Communities Cohort Study

Mun KH, Yu GI, Choi BY, Kim MK, Shin MH, Shin DH

OBJECTIVES: Several studies have investigated the effects of serum uric acid (SUA) levels on chronic kidney disease (CKD), with discrepant results. The effect of SUA levels on CKD development was...
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Induction of Inducible Nitric Oxide Synthase Expression by Manganese in C6 Glioma Cells

Yu GI, Lee DH, Chung IS, Lee MY, Shin DH

  • KMID: 1475121
  • Korean J Occup Environ Med.
  • 2009 Sep;21(3):259-266.
OBJECTIVE: It is well established that manganese neurotoxicity is associated with clinical symptoms similar to those of idiopathic Parkinson's disease. Recent research has shown that the exposure to manganese (MnCl2)...
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