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CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics

Yim EY, Kang HR, Jung JW, Sohn SW, Cho SH

BACKGROUND: Theophylline is mainly metabolized by cytochrome P450 (CYP) 1A2 and CYP2E1 which show inter-individual variations. However, the underlying mechanism remains unknown in humans. We investigated the relationship between differences...
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Association Study between Asthma Severity and Single Nucleotide Polymorphisms of Fibroblast Growth Factor 2

  • KMID: 2234228
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):421-427.
BACKGROUND: Thickening of subepithelial reticular layer is one of the main features of airway remodeling in asthma and is known to be enhanced in severe asthmatics. Fibroblast growth factor 2...
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