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Comparative Study of Two Common In Vitro Models for the Pancreatic Islet with MIN6

Chao X, Zhao F, Hu J, Yu Y, Xie R, Zhong J, Huang M, Zeng T, Yang H, Luo D, Peng W

BACKGROUND: Islet transplantation is currently considered the most promising method for treating insulin-dependent diabetes. The two most-studied artificial islets are alginate-encapsulated b cells or b cell spheroids. As three-dimensional (3D)...
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The Impact of Omicron Wave on Pediatric Febrile Seizure

Joung J, Yang H, Choi YJ, Lee J, Ko Y

Background: The coronavirus disease 2019 (COVID-19) omicron (B.1.1.529) variant reduced the risk of severe disease compared with the original strain and other variants, but it appeared to be highly infectious,...
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Comparison of the Clinical Characteristics of Pediatric Poisoning Patients Who Visited Emergency Department Before and During the COVID-19 Pandemic

Park J, Jeon W, Ko Y, Choi YJ, Yang H, Lee J

Background: We aimed to investigate changes in the clinical characteristics of pediatric poisoning patients who visited the emergency department (ED) before and during the coronavirus disease 2019 (COVID-19) pandemic. Methods: Poisoning...
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Laparoscopic radical cystectomy with pelvic lymph node dissection and ileal orthotopic neobladder by a total extraperitoneal approach: Our initial technique and short-term outcomes

Zhu G, Zhang Z, Zhao K, Yin X, Zhang Y, Wang Z, Li C, Sui Y, Li X, Yang H, Xing N, Wang K

Purpose: With the increasing application of laparoscopic or robot-assisted radical cystectomy, a reliable and promising method is needed for reducing postoperative complications. We describe the short-term outcomes of totally extraperitoneal...
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CircZNF609 Aggravated Myocardial Ischemia Reperfusion Injury via Mediation of miR-214-3p/PTGS2 Axis

Tang WQ, Yang FR, Chen KM, Yang H, Liu Y, Dou B

Background and Objectives: Circular RNAs were known to play vital role in myocardial ischemia reperfusion injury (MIRI), while the role of CircZNF609 in MIRI remains unclear. This study was aimed to...
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A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis

Song S, Zhang Q, Yang H, Guo J, Xu M, Yang N, Yi J, Wang Z, Chen C

Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components...
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Sedentary Time and Fast-Food Consumption Associated With Weight Gain During COVID-19 Lockdown in Children and Adolescents With Overweight or Obesity

Woo S, Yang H, Kim Y, Lim H, Song HJ, Park KH

Background: The coronavirus disease pandemic is predicted to have adverse health effects on children and adolescents who are overweight or obese due to restricted school activity and stay-at-home orders. The...
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A randomized, double‑blind, multicenter, phase III study on the efficacy and safety of a combination treatment involving fimasartan, amlodipine, rosuvastatin in patients with essential hypertension and dyslipidemia who fail to respond adequately to fimasartan monotherapy

Jeon E, Lim S, Kim S, Yang H,  Kim M, Rhee M,  Han S, Shin J, Kim K, Jeong J,  Sung K,  Hong G,  Kim H,  Kwon K, Kang T,  Lee H, Han S

Background: To assess the efficacy and safety of a combination therapy involving fimasartan, amlodipine, and rosuv‑ astatin in patients with essential hypertension and dyslipidemia who fail to respond to fimasartan...
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Simultaneous Determination of Four Compounds from Cercidiphyllum japonicum Using HPLC-UV Analysis

Kang J, Jang HS, Kim JY, Lee MS, Bae YS, Kwon Y, Yang H

Cercidiphyllum japonicum is being used for the treatment of obesity and liver fibrosis in Korean local clinics. In the present study, we tried to develop an analytical methodology for the...
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Sex Comb on Midleg Like-2 Accelerates Hepatocellular Carcinoma Cell Proliferation and Metastasis by Activating Wnt/β-Catenin/EMT Signaling

Du L, Wang L, Yang H, Duan J, Lai J, Wu W, Fan S, Zhi X

Purpose: The purpose of this study was to investigate the influences of sex comb on midleg like-2 (SCML2) on hepatocellular carcinoma (HCC) and potentially related mechanisms. Materials and Methods: SCML2 expression...
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Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaCl 2 negatively regulates neurosphere formation in culture

Kwon JK, Choi DJ, Yang H, Ko DW, Jou I, Park SM, Joe EH

Astrocytes are activated in response to brain damage. Here, we found that expression of Kir4.1, a major potassium channel in astrocytes, is increased in activated astrocytes in the injured brain...
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Associated Factors of Depression and Suicidal Behaviors among Korean Adolescents: Web-based Survey of the Korea Youth Risk Behavior in 2015~2017

Choi HA, Yang H

Purpose: Suicide among adolescents is a serious problem worldwide, and especially, the suicide rate of teenagers is increasing rapidly in South Korea. This study was conducted to investigate the factors...
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A New Phenolic Compound from Lespedeza tomentosa

Jang HS, Choi SY, Yang H, Kim MJ, Chun W, Kwon Y

A new phenolic compound and three known flavonoids isolated from the MeOH extracts of Lespedeza tomentosa. Based on spectral data, the isolated compounds were identified as methyl 4,5-dihydroxy-3-methoxy-2-(3-methylbut-2-en-1-yl)benzoate (1), 1-methoxylespeflorin...
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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Cytotoxic Lesion of the Corpus Callosum (CLOCCs) after SARS-CoV-2 mRNA Vaccination

Youn T, Yang H

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Musculoskeletal Injuries by Weapons in Korean Soldiers: Four-Year Follow-Up

Yang H, Hwang IU, Song D, Moon GH, Lee NR, Kim KN

Purpose: To date, studies of firearm and explosive injuries in the Korean military have been limited compared to its importance. To overcome this, this study examined the characteristics of musculoskeletal...
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Percutaneous Renal Tumor Biopsy in Small Renal Masses

Yang H, Kim K, Jeon Y

With increased use of abdominal imaging studies, the diagnosis of kidney cancer has shifted toward early diagnoses of renal masses. Most of those tumors are small in sized. Treatment decision...
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Factors affecting stigma communication towards people living with HIV/AIDS

Kim HW, Yang H

Purpose: This study aims to identify factors influencing the stigma communication concerning HIV (Human Immunodeficiency Virus)/AIDS (Acquired Immune Deficiency Syndrome) patients between health and medical college students. Methods: In this...
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Imaging Assessment of Visceral Pleural Surface Invasion by Lung Cancer: Comparison of CT and Contrast-Enhanced Radial T1-Weighted Gradient Echo 3-Tesla MRI

Zhang Y, Kwon W, Lee HY, Ko SM, Kim SH, Lee WY, Yong SJ, Jung SH, Byun CS, Lee J, Yang H, Han J, Ackman JB

Objective: To compare the diagnostic performance of contrast-enhanced radial T1-weighted gradient-echo 3-tesla (3T) magnetic resonance imaging (MRI) and computed tomography (CT) for the detection of visceral pleural surface invasion (VPSI)....
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Risk factor leading to complicated appendicitis: pelvic position of the appendix

Koh H, Yang H, Cho K, Jung YY, Chang YS, Kim DH, Kim MS

  • KMID: 2515963
  • J Korean Soc Emerg Med.
  • 2021 Apr;32(2):134-142.
Objective: Several factors contribute to the progression of complicated appendicitis (CA) in patients diagnosed with acute appendicitis. The goal of this study was to investigate whether the pelvic location of...
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