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Investigating the Prevalence of Dementia and Its Associated Risk Factors in a Chinese Nursing Home

Xu S, Jin X, Liu C, Jin Y, Xu Y, Chen L, Xu S, Tang H, Yan J

BACKGROUND AND PURPOSE: The objective of this study was to determine the prevalence of and risk factors for dementia in residents aged 65 years and older in a Chinese nursing...
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Preparation, characterization, and in vivo evaluation of a polymorphic form of valnemulin hydrogen tartrate

Zhu X, Xu S, Lu L, Wang S, Zhao Q, Li D, Li J, Zhao H, Xu B

We prepared a polymorphic form of valnemulin hydrogen tartrate (Form I) to overcome the instability and irritating odor of valnemulin hydrochloride that affect its use in the production and application...
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Predicting Pathological Complete Response in Breast Cancer After Two Cycles of Neoadjuvant Chemotherapy by Tumor Reduction Rate: A Retrospective Case-Control Study

Yao L, Liu X, Wang M, Yu K, Xu S, Qiu P, Lv Z, Zhang X, Xu Y

Purpose: We aimed to identify effectiveness-associated indicators and evaluate the optimal tumor reduction rate (TRR) after two cycles of neoadjuvant chemotherapy (NAC) in patients with invasive breast cancer. Methods: This retrospective...
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Human B1 Cells are the Main Blood Group A-Specific B Cells That Have a Moderate Correlation With Anti-A Antibody Titer

Xu Y, Lee JG, Yan JJ, Ryu JH, Xu S, Yang J

BACKGROUND: Anti-carbohydrate antibody responses, including those of anti-blood group ABO antibodies, are yet to be thoroughly studied in humans. Because anti-ABO antibody-mediated rejection is a key hurdle in ABO-incompatible transplantation,...
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Human Population Admixture in Asia

Xu S

Genetic admixture in human, the result of inter-marriage among people from different well-differentiated populations, has been extensively studied in the New World, where European colonization brought contact between peoples of...
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Improving Acetabular Component Positioning in Supine Direct Anterior Total Hip Arthroplasty with a Transparency Template: A Novel, Simple, and Cost-effective Technique

Xu S, Lim JBT, Pang HN

Purpose: A novel and simple method to ensure accurate acetabular component anteversion and inclination intraoperatively with the use of a transparency template is described. Materials and Methods: Patients who underwent total...
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Association between Working Hours and Anxiety/Depression of Medical Staff during Large-Scale Epidemic Outbreak of COVID-19: A Cross-Sectional Study

Lang Q, Liu X, He Y, Lv Q, Xu S

Objective: This present study aimed to investigate the relationship between working hours and anxiety/depression mood of medical staff in China during COVID-19 epidemic. Methods: The cross-sectional interview study was conducted during...
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SURF4 maintains stem-like properties via BIRC3 in ovarian cancer cells

Yue Y, Xia L, Xu S, Wang C, Wang X, Lu W, Xie X

Objective: As cancer stem cells (CSCs) are considered as the origin of tumor development, recurrence, and drug resistance, we aimed to explore the mechanism related to modulating stemness in CSCs,...
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A Case of Simultaneously Diagnosed Lung Adenocarcinoma and Endobronchial Inflammatory Myofibroblastic Tumor with Two Distinct Types of ALK Translocation

Zhao S, Liu W, Li S, Shi T, Chen Q, Li Q, Sun L, Ren D, Song Z, Huang C, Xu S

A 61-year-old male patient was simultaneously diagnosed with lung adenocarcinoma and inflammatory myofibroblastic tumor (IMT). The lung adenocarcinoma and IMT harbored two distinct types of ALK translocation, LOC101927285-ALK, and TPM3-ALK,...
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Maternal Separation Induced Visceral Hypersensitivity from Childhood to Adulthood

Yi L, Zhang H, Sun H, Zhou L, Chen Y, Xuan L, Jiang Y, Xu S

  • KMID: 2433532
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):306-315.
  • doi: 10.5056/jnm16089
BACKGROUND/AIMS: Early adverse life events (EALs) are relevant to irritable bowel syndrome in adulthood. Maternal separation (MS), as one of the EALs, has proved to induce visceral hypersensitivity in adult...
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Effect of phosphorus deficiency on erythrocytic morphology and function in cows

Zhang Z, Bi M, Yang J, Yao H, Liu Z, Xu S

The aim of this study was to evaluate the influence of phosphorus (P) deficiency on the morphological and functional characteristics of erythrocytes in cows. Forty Holstein-Friesian dairy cows in mid-lactation...
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Baseline extent of damage predicts spinal radiographic progression in Korean patients with ankylosing spondylitis treated with golimumab

Lee JS, Song YW, Kim TH, Chung WT, Lee SG, Park SH, Song GG, Yu DY, Xu S, Lee EY

BACKGROUND/AIMS: For patients with ankylosing spondylitis (AS), golimumab has consistent efficacy in controlling disease activity over 5 years but its benefit in preventing radiographic progression was less clear at 4...
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Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes

Ly LD, Xu S, Choi SK, Ha CM, Thoudam T, Cha SK, Wiederkehr A, Wollheim C, Lee IK, Park KS

Free fatty acids (FFAs) are important substrates for mitochondrial oxidative metabolism and ATP synthesis but also cause serious stress to various tissues, contributing to the development of metabolic diseases. CD36...
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Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition

Wang X, Ma S, Wu H, Shen X, Xu S, Guo X, Bolick ML, Wu S, Wang F

Our previous works disclosed the contributing role of macrophage migration inhibitory factor (MIF) and dopaminergic inhibition by lysine dimethyltransferase G9a/Glp complex in peripheral nerve injury-induced hypersensitivity. We herein propose that...
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Sustained release of alginate hydrogel containing antimicrobial peptide Chol-37(F34-R) in vitro and its effect on wound healing in murine model of Pseudomonas aeruginosa infection

Shi S, Dong H, Chen X, Xu S, Song Y, Li M, Yan Z, Wang X, Niu M, Zhang M, Liao C

Background: Antibiotic resistance is a significant public health concern around the globe. Antimicrobial peptides exhibit broad-spectrum and efficient antibacterial activity with an added advantage of low drug resistance. The higher water...
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Impact of Cigarette Smoking: a 3-Year Clinical Outcome of Vasospastic Angina Patients

Choi BG, Rha SW, Park T, Choi SY, Byun JK, Shim MS, Xu S, Li H, Park SH, Park JY, Choi WG, Cho YH, Lee S, Na JO, Choi CU, Lim HE, Kim JW, Kim EJ, Park CG, Seo HS, Oh DJ

BACKGROUND AND OBJECTIVES: Cigarette smoking is a risk significant factor in coronary artery disease (CAD) and vasospastic angina (VSA). However, it is largely unknown whether smoking adds to any long-term...
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