- Understanding Muscle Protein Dynamics: Technical Considerations for Advancing Sarcopenia Research
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Kim IY, Park S, Jang J, Wolfe RR
- KMID: 2506918
- Ann Geriatr Med Res.
- 2020 Sep;24(3):157-165.
- doi: 10.4235/agmr.20.0041
Sarcopenia, which is the loss of muscle mass and strength that occur with aging, involves imbalanced muscle protein turnover (i.e., protein breakdown exceeding synthesis), which in turn exacerbates other clinical... -
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- Applications of stable, nonradioactive isotope tracers in in vivo human metabolic research
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Kim IY, Suh SH, Lee IK, Wolfe RR
- KMID: 2327676
- Exp Mol Med.
- 2016 Jan;48(1):e203.
- doi: 10.1038/emm.2015.97
The human body is in a constant state of turnover, that is, being synthesized, broken down and/or converted to different compounds. The dynamic nature of in vivo kinetics of human... -
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- In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench
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Kim IY, Park S, Kim Y, Chang Y, Choi CS, Suh SH, Wolfe RR
- KMID: 2511000
- Endocrinol Metab.
- 2020 Dec;35(4):733-749.
- doi: 10.3803/EnM.2020.406
Like other substrates, plasma glucose is in a dynamic state of constant turnover (i.e., rates of glucose appearance [Ra glucose] into and disappearance [Rd glucose] from the plasma) while staying... -
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- Quantifications of Lipid Kinetics In Vivo Using Stable Isotope Tracer Methodology
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Kim IY, Park S, Jang J, Wolfe RR
- KMID: 2470804
- J Lipid Atheroscler.
- 2020 Jan;9(1):110-123.
- doi: 10.12997/jla.2020.9.1.110
Like other bodily materials, lipids such as plasma triacylglycerol, cholesterols, and free fatty acids are in a dynamic state of constant turnover (i.e., synthesis, breakdown, oxidation, and/or conversion to other... -
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