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Is a Patient With Asymptomatic Esophagitis Really Hyposensitive to Acid and Distention?

Yamasaki T, Watari J, Oshima T, Tomita T, Miwa H

  • KMID: 2325824
  • J Neurogastroenterol Motil.
  • 2011 Jul;17(3):318-319.
No abstract available.
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Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of Helicobacter pylori Eradication and Aspirin

Watari J, Tomita T, Tozawa K, Oshima T, Fukui H, Miwa H

Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of...
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Esophageal Sensation and Esophageal Hypersensitivity: Overview From Bench to Bedside

Miwa H, Kondo T, Oshima T, Fukui H, Tomita T, Watari J

  • KMID: 2204231
  • J Neurogastroenterol Motil.
  • 2010 Oct;16(4):353-362.
Noxious stimuli in the esophagus activate nociceptive receptors on esophageal mucosa, such as transient receptor potential, acid-sensing ion channel and the P2X family, a family of ligand-gated ion channels responsive...
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Prevalence and Self-recognition of Chronic Constipation: Results of an Internet Survey

Tamura A, Tomita T, Oshima T, Toyoshima , Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ikehara H, Ohda Y, Fukui H, Watari J, Miwa H

  • KMID: 2433461
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):677-685.
  • doi: 10.5056/jnm15187
BACKGROUND/AIMS: Although chronic constipation is a common symptom, to date no international consensus has been reached regarding its definition. The aims of this study were (1) to investigate defecation habits...
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Esophagography in Patients With Esophageal Achalasia Diagnosed With High-resolution Esophageal Manometry

Yamasaki T, Tomita T, Mori S, Takimoto M, Tamura A, Hara K, Kondo T, Kono T, Tozawa K, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H

  • KMID: 2417384
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):403-409.
  • doi: 10.5056/jnm17147
BACKGROUND/AIMS: High-resolution esophageal manometry (HREM) is considered to be the gold standard for the diagnosis of achalasia. However, the Japan Esophageal Society recommends that esophagography is also accurate in either...
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Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia

Asano H, Tomita T, Nakamura K, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ohda Y, Oshima T, Fukui H, Fukushima , Hirota S, Watari J, Miwa H

  • KMID: 2387830
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):392-399.
  • doi: 10.5056/jnm16173
BACKGROUND/AIMS: Gastric motility abnormalities have been considered to be pathophysiological features of functional dyspepsia (FD) that are closely related to dyspepsia symptoms, especially postprandial distress syndrome (PDS). The aims of...
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Intravenous Corticotropin-releasing Hormone Administration Increases Esophageal Electrical Sensitivity in Healthy Individuals

Yamasaki T, Tomita T, Takimoto M, Kondo T, Tozawa K, Ohda Y, Oshima T, Fukui H, Watari J, Miwa H

  • KMID: 2395420
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):526-532.
  • doi: 10.5056/jnm17067
BACKGROUND/AIMS: When a person is experiencing stress, corticotropin-releasing hormone (CRH) can modulate gut physiologies, such as visceral sensation or gastrointestinal motility, and its intravenous administration mimics stress-induced physiological changes. However,...
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A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation

Mori S, Tomita T, Fujimura K, Asano H, Ogawa T, Yamasaki T, Kondo T, Kono T, Tozawa K, Oshima T, Fukui H, Kimura T, Watari J, Miwa H

  • KMID: 2460486
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):563-575.
  • doi: 10.5056/jnm18194
BACKGROUND/AIMS: Magnesium oxide (MgO) has been frequently used as a treatment for chronic constipation (CC) since the 1980s in Japan. The aim of this study is to evaluate its therapeutic...
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Prevalence of Irritable Bowel Syndrome–like Symptoms in Japanese Patients with Inactive Inflammatory Bowel Disease

Tomita T, Kato Y, Takimoto M, Yamasaki T, Kondo T, Kono T, Tozawa K, Yokoyama Y, Ikehara H, Ohda Y, Oshima T, Fukui H, Tanaka S, Shima M, Watari J, Miwa H

  • KMID: 2433459
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):661-669.
  • doi: 10.5056/jnm15160
BACKGROUND/AIMS: Few studies are available that have investigated the risk factors for overlapping irritable bowel syndrome (IBS)-like symptoms in patients with inactive inflammatory bowel disease (IBD). The present study has...
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