- Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells
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Kim SH, Yeo GS, Lim YS, Kang CD, Kim CM, Chung BS
- KMID: 754993
- Exp Mol Med.
- 1998 Jun;30(2):87-92.
MDR1 promoter has been shown to contain heat shock elements (HSE), and it has been reported that FM3A/M and P388/M MDR cells show a constitutively activated heat shock factor (HSF), suggesting that... -
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- Disruption of Microtubules Sensitizes the DNA Damage-induced Apoptosis Through Inhibiting Nuclear Factor kappaB (NF-kappaB) DNA-binding Activity
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Lee H, Jeon J, Ryu YS, Jeong JE, Shin S, Zhang T, Kang SW, Hong JH, Hur GM
- KMID: 1779226
- J Korean Med Sci.
- 2010 Nov;25(11):1574-1581.
- doi: 10.3346/jkms.2010.25.11.1574
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-kappaB) activity. The exact molecular mechanism by which microtubule rearrangement... -
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