- 6-Shogaol reduces progression of experimental endometriosis in vivo and in vitro via regulation of VGEF and inhibition of COX-2 and PGE2-mediated inflammatory responses
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Wang D, Jiang Y, Yang X, Wei Q, Wang H
- KMID: 2430085
- Korean J Physiol Pharmacol.
- 2018 Nov;22(6):627-636.
- doi: 10.4196/kjpp.2018.22.6.627
Endometriosis (EM) is one of the most common gynaecological disorder affecting women in their reproductive age. Mechanisms involved in the pathogenesis of EM remains poorly understood, however inflammatory responses have... -
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- Isomangiferin, a Novel Potent Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor, Suppresses Breast Cancer Growth, Metastasis and Angiogenesis
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Wang B, Shen J, Wang Z, Liu J, Ning Z, Hu M
- KMID: 2441863
- J Breast Cancer.
- 2018 Mar;21(1):11-20.
- doi: 10.4048/jbc.2018.21.1.11
PURPOSE: Vascular endothelial growth factor (VEGF) signal transduction mainly depends on its binding to VEGF receptor 2 (VEGFR-2). VEGF downstream signaling proteins mediate several of its effects in cancer progression,... -
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- Effect of Anti-vascular Endothelial Growth Factor Antibody on the Survival of Cultured Retinal Ganglion Cells
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Lee JM, Bae HW, Lee SY, Seong GJ, Kim CY
- KMID: 2385586
- Korean J Ophthalmol.
- 2017 Aug;31(4):360-365.
- doi: 10.3341/kjo.2017.0054
PURPOSE: To investigate the effects of anti-vascular endothelial growth factor (VEGF) antibody on the survival of retinal ganglion cell (RGC)-5 cells differentiated with staurosporine under oxidative stress. METHODS: We used real-time... -
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- Tea Flavonoids Induced Differentiation of Peripheral Blood-derived Mononuclear Cells into Peripheral Blood-derived Endothelial Progenitor Cells and Suppressed Intracellular Reactive Oxygen Species Level of Peripheral Blood-derived Endothelial Progenitor Cells
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Widowati W, Wijaya L, Laksmitawati DR, Widyanto R, Erawijantari PP, Fauziah N, Bachtiar I, Sandra F
- KMID: 2328872
- Nat Prod Sci.
- 2016 Jun;22(2):87-92.
- doi: 10.20307/nps.2016.22.2.87
Endothelial dysfunction in atherosclerosis is associated with increasing oxidative stress that could be reversed by antioxidant. Therefore epigallocatechin gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and catechin (C) of tea... -
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- Comparative Evaluation for Potential Differentiation of Endothelial Progenitor Cells and Mesenchymal Stem Cells into Endothelial-Like Cells
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Sabry D, Noh O, Samir M
- KMID: 2164160
- Int J Stem Cells.
- 2016 May;9(1):44-52.
- doi: 10.15283/ijsc.2016.9.1.44
Understanding the mechanisms of vascular remodeling could lead to more effective treatments for ischemic conditions. We aimed to compare between the abilities of both human Wharton jelly derived mesenchymal stem... -
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- Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis
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Park JH, Park GM, Kim JK
- KMID: 2285576
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):335-340.
- doi: 10.4196/kjpp.2015.19.4.335
Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and... -
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- Effect of Endogenous Bone Marrow Derived Stem Cells Induced by AMD-3100 on Expanded Ischemic Flap
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Jeong HS, Lee HK, Tark KC, Lew DH, Koh YW, Kim CH, Seo IS
- KMID: 2151419
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S237-S248.
- doi: 10.3346/jkms.2014.29.S3.S237
The purpose of this study was to devise an expanded ischemic flap model and to investigate the role of AMD-3100 (Plerixafor, chemokine receptor 4 inhibitor) in this model by confirming... -
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- Angiokeratoma circumscriptum of the buccal mucosa: a case report and literature review
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Kang YH, Byun JH, Park BW
- KMID: 2005454
- J Korean Assoc Oral Maxillofac Surg.
- 2014 Oct;40(5):240-245.
- doi: 10.5125/jkaoms.2014.40.5.240
Angiokeratoma is a benign cutaneous lesion of the capillaries, presenting as dilated vessels in the upper part of the dermis. Although this disorder is classified into various types and has... -
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- Expression of Semaphorin 3A and Neuropilin 1 in Asthma
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Shim EJ, Chun E, Kang HR, Cho SH, Min KU, Park HW
- KMID: 1777678
- J Korean Med Sci.
- 2013 Oct;28(10):1435-1442.
- doi: 10.3346/jkms.2013.28.10.1435
Neuropilin 1 (NP1) is a part of essential receptor complexes mediating both semaphorin3A (SEMA3A) and vascular endothelial growth factor (VEGF) which is one of important mediators involved in the pathogenesis... -
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- Radiation up-regulates the expression of VEGF in a canine oral melanoma cell line
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Flickinger I, Rutgen BC, Gerner W, Calice I, Tichy A, Saalmuller A, Kleiter M
- KMID: 1705523
- J Vet Sci.
- 2013 Jun;14(2):207-214.
- doi: 10.4142/jvs.2013.14.2.207
To evaluate radiosensitivity and the effects of radiation on the expression of vascular endothelial growth factor (VEGF) and VEGF receptors in the canine oral melanoma cell line, TLM 1, cells... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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- In Vitro and In Vivo Imaging of Prostate Cancer Angiogenesis Using Anti-Vascular Endothelial Growth Factor Receptor 2 Antibody-Conjugated Quantum Dot
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Kwon H, Lee J, Song R, Hwang SI, Lee J, Kim YH, Lee HJ
- KMID: 1430041
- Korean J Radiol.
- 2013 Feb;14(1):30-37.
- doi: 10.3348/kjr.2013.14.1.30
OBJECTIVE: Authors aimed to determine the targeting ability of vascular endothelial growth factor receptor 2 (VEGFR2)-conjugated quantum dots (QDs) in vitro, and apply it for a xenograft prostate cancer mouse... -
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- Photosensitivity Reactions to Vandetanib: Redevelopment after Sequential Treatment with Docetaxel
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Son YM, Roh JY, Cho EK, Lee JR
- KMID: 2171860
- Ann Dermatol.
- 2011 Dec;23(Suppl 3):S314-S318.
- doi: 10.5021/ad.2011.23.S3.S314
Vandetanib (ZD6474, Zactima(TM)) is a novel, orally available inhibitor of different intracellular signaling pathways involved in tumor growth, progression, and angiogenesis, including vascular endothelial growth factor receptor-2, epidermal growth factor... -
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- Radiological Apoplexy and Its Correlation with Acute Clinical Presentation, Angiogenesis and Tumor Microvascular Density in Pituitary Adenomas
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Lee JS, Park YS, Kwon JT, Nam TK, Lee TJ, Kim JK
- KMID: 2190382
- J Korean Neurosurg Soc.
- 2011 Oct;50(4):281-287.
- doi: 10.3340/jkns.2011.50.4.281
OBJECTIVE: Pituitary apoplexy is life-threatening clinical syndrome caused by the rapid enlargement of a pituitary tumor due to hemorrhage and/or infarction. The pathogenesis of pituitary apoplexy is not completely understood.... -
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- Inhibition of Lymphatic Endothelial Growth Factor Receptor in a Murine Model of Oral Squamous Cell Carcinoma
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Kye JY, Park YW
- KMID: 2136910
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2011 Jan;33(1):1-9.
PURPOSE: Tumor associated angiogenesis and/or lymphangiogenesis are known to be linked by VEGFR signaling pathways. These processes are regulated by several growth factors including VEGFR-2, VEGFR-3. E7080 is an orally... -
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- Differences in Expression of VEGF-A, VEGFR-1, VEGFR-2 and Microvessel Density in Colorectal Cancer with Liver Metastasis
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Jeong EH, Kim Y, Min BW, Lee KH, Kim HS, Lee JH
- KMID: 2277533
- Korean J Pathol.
- 2010 Dec;44(6):571-580.
BACKGROUND: Colorectal cancer (CRC) is one of the most common malignant neoplasms and is a leading cause of mortality worldwide. Metastasis to the liver is a frequent event in patients... -
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- Visualization of Tumor Angiogenesis Using MR Imaging Contrast Agent Gd-DTPA-anti-VEGF Receptor 2 Antibody Conjugate in a Mouse Tumor Model
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Jun HY, Yin HH, Kim SH, Park SH, Kim HS, Yoon KH
- KMID: 984899
- Korean J Radiol.
- 2010 Aug;11(4):449-456.
- doi: 10.3348/kjr.2010.11.4.449
OBJECTIVE: To visualize tumor angiogenesis using the MRI contrast agent, Gd-DTPA-anti-VEGF receptor 2 antibody conjugate, with a 4.7-Tesla MRI instrument in a mouse model. MATERIALS AND METHODS: We designed a... -
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- VEGF-related Autocrine Growth in Periosteal-Derived Cells
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Park BW, Lee SG, Hah YS, Kim DR, Cho YC, Sung IY, Kim UK, Kim JR, Byun JH
- KMID: 1474201
- J Korean Assoc Oral Maxillofac Surg.
- 2009 Oct;35(5):294-298.
PURPOSE: The development of a microvascularization is important for the homeostasis of normal bone. Vascular endothelial growth factor (VEGF) is one of the most important factors in vessel formation. The... -
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- Soluble and Membranous Vascular Endothelial Growth Factor Receptor-2 in Pregnancies Complicated by Pre-Eclampsia
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Tripathi R, Rath G, Ralhan R, Saxena S, Salhan S
- KMID: 1103819
- Yonsei Med J.
- 2009 Oct;50(5):656-666.
- doi: 10.3349/ymj.2009.50.5.656
PURPOSE: There is a paucity of information on the serum soluble vascular endothelial growth factor receptor-2 (sVEGFR-2) concentrations, membranous VEGFR-2 expression and the mechanism involved in their modulations during the... -
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- Proliferation of endothelial progenitor cells by osteogenic differentiation of periosteal-derived cells
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Kim JR, Song JH, Kim UK, Park BW, Hah YS, Kim JH, Kim DR, Cho YC, Sung IY, Byun JH
- KMID: 1474220
- J Korean Assoc Oral Maxillofac Surg.
- 2009 Aug;35(4):205-212.
PURPOSE : The purpose of this study was to examine the expression of various angiogenic factors during osteoblastic differentiation of periostealderived cells and the effects of osteogenic inductive medium of... -
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