- IMMUNOHISTOCHEMICAL STUDY ON EXPRESSION OF LYMPHANGIOGENIC FACTORS IN ORAL CANCER
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Park YW, Kwon KJ, Lee JW
- KMID: 2005089
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2010 Jan;32(1):1-8.
BACKGROUND AND PURPOSE: Vascular endothelial growth factor (VEGF)-C and VEGF receptor (VEGFR)-3 are involved in tumor lymphangiogenesis. Oral mucosal squamous cell carcinoma (OMSCC) preferentially metastasizes to cervical lymph nodes, so... -
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- Expression of Vascular Endothelial Growth Factors A,C and D in Gastric Adenocarcinoma
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Chung MJ, Lee JW, Yu KH, Yang DH, Jang KY, Moon WS, Kang MJ, Lee DG
- KMID: 2275426
- Korean J Pathol.
- 2005 Apr;39(2):99-105.
BACKGROUND: Vascular endothelial growth factor (VEGF)-C and VEGF-D are novel growth factors that regulate lymphatic vessel growth. This study was designed to examine whether the expression of three VEGF family... -
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- Expression of Placenta Growth Factor in the Oral Squamous Cell Carcinoma
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Lee SG, Kim CH
- KMID: 2186651
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2009 Jan;31(1):27-34.
Angiogenesis is essential for solid tumor growth and progression. Among the pro-angiogenetic factors, vascular endothelial growth factor(VEGF), also known as vascular permeability factor, is the most important as a mitogen... -
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- Metastasis via Peritumoral Lymphatic Dilation in Oral Squamous Cell Carcinoma
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Kim HS, Park YW
- KMID: 1910868
- Maxillofac Plast Reconstr Surg.
- 2014 May;36(3):85-93.
PURPOSE: Nodal metastasis is the main prognostic factor in the patients with oral squamous cell carcinoma (OSCC). We investigated the association between tumor-associated lymphatics and OSCC characteristics. METHODS: Thirty-four specimens were... -
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- Clinical Significance of Vascular Endothelial Growth Factors (VEGF)-C and -D in Resected Non-Small Cell Lung Cancer
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Ko YH, Jung CK, Lee MA, Byun JH, Kang JH, Lee KY, Jo KH, Wang YP, Hong YS
- KMID: 1804615
- Cancer Res Treat.
- 2008 Sep;40(3):133-140.
PURPOSE: Lymphatic spread of tumor is an important prognostic factor for patients with non-small cell lung carcinoma (NSCLC). Vascular endothelial growth factor-C (VEGF-C) and VEGF-D play important roles in lymphangiogenesis... -
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- STAT3, a Poor Survival Predicator, Is Associated with Lymph Node Metastasis from Breast Cancer
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Chen Y, Wang J, Wang X, Liu X, Li H, Lv Q, Zhu J, Wei B, Tang Y
- KMID: 2374543
- J Breast Cancer.
- 2013 Mar;16(1):40-49.
PURPOSE: The aim of this study is to explore signal transducer and activator of transcription 3 (STAT3) expression in breast cancer and to analyze the detailed mechanism that STAT3 contributes... -
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- The Expression of Vascular Endothelial Growth Factor (VEGF)-C and VEGF-D in Early Gastric Cancer That's Invaded the Submucosa
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Kim JG, Choi MG, Park WS, Lee SC, Lee DH, You YK, Ahn CJ, Park CH
- KMID: 2324761
- J Korean Surg Soc.
- 2008 Jan;74(1):48-53.
PURPOSE: Vascular endothelial growth factor (VEGF)-C and VEGF-D are considered novel growth factors that potentially induce lymphangiogenesis and hyperplasia of lymphatic vessels. The aim of this study was to investigate... -
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- Correlation of Vascular Endothelial Growth Factor-D Expression and VEGFR-3-Positive Vessel Density with Lymph Node Metastasis in Gastric Carcinoma
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Choi JH, Oh YH, Park YW, Baik HK, Lee YY, Kim IS
- KMID: 1785815
- J Korean Med Sci.
- 2008 Aug;23(4):592-597.
- doi: 10.3346/jkms.2008.23.4.592
Lymph node metastasis is an important prognostic factor in gastric cancer. Vascular endothelial growth factor-D (VEGF-D) is a lymphangiogenic growth factor that activates VEGF receptor (VEGFR)-3, a receptor expressed in... -
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- Prediction of Invasiveness by the Expressions of CD105 (Endoglin), D2-40 and Vascular Endothelial Growth Factors A and D in the Endoscopic Biopsy Tissue of Stomach Cancer Patients
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Kim S, Lee TJ, Kim BK, Cha SJ, Park SJ, Chang IT, Park SI
- KMID: 2324883
- J Korean Surg Soc.
- 2007 May;72(5):358-368.
PURPOSE: CD105 (endoglin) has been shown to be a more useful marker to identify the proliferating endothelium involved in tumor angiogenesis than are the panendothelial markers. The monoclonal antibody D2-40... -
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- Establishment and Characterization of Human Lymphatic Endothelial Cell in Breast Cancer Patients Undergoing Sentinel Lymphadenectomy
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Takeda A
- KMID: 2175195
- J Breast Cancer.
- 2009 Jun;12(2):61-66.
- doi: 10.4048/jbc.2009.12.2.61
Recently remarkable progress has been made in the understanding of lymphangiogenesis due to the availability of specific biomarkers. A sentinel lymph node (SLN) biopsy has already been established as a... -
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- Comparative Analysis of Vascular Endothelial Growth Factor-A, C, D Expression in Colorectal Cancer with Liver Metastasis
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Chun KS, Lee KH, Song IS, Kim JY, Kim JR, Ahn MS, Lee SI, Park JH, Choi SE, Kang DY, Song KS
- KMID: 2096551
- J Korean Surg Soc.
- 2009 May;76(5):307-315.
- doi: 10.4174/jkss.2009.76.5.307
PURPOSE: We aimed to investigate the correlations between expressions of angiogenic cytokines VEGF-A, C, D of primary colorectal cancer and liver metastasis. METHODS: We examined paraffin-embedded primary colorectal cancer tissue... -
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- Association Between c-Met and Lymphangiogenic Factors in Patients With Colorectal Cancer
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Kim HJ, Baek MJ, Kang DH, Lee SC, Bae SB, Lee KT, Lee N, Kim H, Jeong D, Ahn TS, Lee MS, Hong DS, Won JH
- KMID: 2411567
- Ann Coloproctol.
- 2018 Apr;34(2):88-93.
- doi: 10.3393/ac.2017.10.10
PURPOSE: Animal models show a strong relationship between lymphangiogenesis and lymph node metastasis. However, the clinical significance of lymphangiogenesis in patients with colorectal cancer (CRC) remains uncertain. This study aimed... -
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- Clinical Significance of VEGF-C and COX-2 Expression in Gastric Carcinoma with Submucosal Invasion
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Cho YJ, Lee JU, Lee KJ, Park CH, Park SM, Jeon HM, Ahn CJ, Kim JG, Lee DH, Lee SC
- KMID: 2333665
- J Korean Gastric Cancer Assoc.
- 2009 Sep;9(3):96-103.
PURPOSE: Lymph node metastasis is an important factor in determining prognosis and therapeutic options for early gastric cancer (EGC) patients. Vascular endothelial growth factor (VEGF)-C and D are known as... -
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- Gene Expression for Lymphangiogenic Factors in Oral Mucosal Squamous Cell Carcinoma
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Park YW, Kim SG, Kim SH, Kim HS, Kim MK
- KMID: 1474262
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2009 Nov;31(6):453-460.
BACKGROUND AND PURPOSE: Vascular endothelial growth factor (VEGF)-C, VEGF-D and their tyrosine kinase receptor, VEGF receptor (VEGFR)-3 are recently known to have lymphangiogenic activities in various tumor types. Oral mucosal... -
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- Benzodiazepine-Associated Carcinogenesis: Focus on Lorazepam-Associated Cancer Biomarker Changes in Overweight Individuals
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Ku SC, Ho PS, Tseng YT, Yeh TC, Cheng SL, Liang CS
- KMID: 2424023
- Psychiatry Investig.
- 2018 Sep;15(9):900-906.
- doi: 10.30773/pi.2018.05.02.1
OBJECTIVE: Cellular, animal, and human epidemiological studies suggested that benzodiazepines increase the risk of cancer and cancer mortality. Obesity is also clearly linked to carcinogenesis. However, no human studies have... -
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- The Correlation between the Expression of E-cadherin, VEGF-C, VEGF-D and the Real Extent of Lymph Node Metastases using Cytokeratin 18 in Early Gastric Cancer
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Kim DH, Yun HY, Song YJ, Ryu DH, Min IC, Sung R, Lee SE
- KMID: 2372870
- J Korean Gastric Cancer Assoc.
- 2008 Jun;8(2):70-78.
PURPOSE: VEGF-C and VEGF-D are angiogenetic factors, and abnormal expression of E-cadherin hasa role in the progression of gastric carcinoma. The aim of this study was to evaluate the relationship... -
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- Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of acute myocardial infarction
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Park JH, Yoon JY, Ko SM, Jin SA, Kim JH, Cho CH, Kim JM, Lee JH, Choi SW, Seong IW, Jeong JO
- KMID: 1022123
- Exp Mol Med.
- 2011 Aug;43(8):479-485.
- doi: 10.3858/emm.2011.43.8.054
Cardiac lymphatic system in the remodeling after acute myocardial infarction (AMI) has been overlooked. We wanted to investigate the role of bone marrow-derived endothelial progenitor cells (EPCs) and their contribution... -
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