- Adverse Skin Reactions with Antiepileptic Drugs Using Korea Adverse Event Reporting System Database, 2008–2017
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Kim HK, Kim DY, Bae EK, Kim DW
- KMID: 2468519
- J Korean Med Sci.
- 2020 Feb;35(4):e17.
- doi: 10.3346/jkms.2020.35.e17
BACKGROUND: Severe and life-threatening drug eruptions include drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). One class of medications that has been... -
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- Antiphospholipid and Antinuclear Antibodies in Children with Idiopathic Epilepsy: A 2-Year Prospective Study
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Attilakos , Fotis L, Dinopoulos A, Alexopoulos H, Theofilopoulou AV, Tzioufas A, Mastroyianni S, Karalexi M, Garoufi A
- KMID: 2467796
- J Clin Neurol.
- 2020 Jan;16(1):140-144.
- doi: 10.3988/jcn.2020.16.1.140
BACKGROUND AND PURPOSE: The high prevalence of antiphospholipid antibodies (aPL) and antinuclear antibodies (ANA) in patients with epilepsy may be associated with either the disease itself or the antiepileptic treatment.... -
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- Valproate Induced Hair Loss and Curly Hair in Bipolar Disorder
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Uygur OF, Uygur H
- KMID: 2464728
- Clin Psychopharmacol Neurosci.
- 2019 Nov;17(4):566-567.
- doi: 10.9758/cpn.2019.17.4.566
No abstract available. -
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- Prosopometamorphopsia and Visual Field Defect Improved by Valproic acid in a CADASIL Patient
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Hwangbo J, Cho JW, Jung SH, Shin JH, Jung NY
- KMID: 2464140
- J Korean Neurol Assoc.
- 2019 Nov;37(4):368-371.
- doi: 10.17340/jkna.2019.4.5
Persistent aura without infarction is defined as an aura persisting for 1 week or more without evidence of infarction on neuroimaging. It is difficult to differentiate persistent visual aura without... -
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- Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea
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Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH, Korean Registry of Severe Cutaneous Adverse Reactions Consortium
- KMID: 2452760
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):709-722.
- doi: 10.4168/aair.2019.11.5.709
PURPOSE: Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) to antiepileptic drug (AED), are rare, but... -
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- HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice
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Kim T, Song S, Park Y, Kang S, Seo H
- KMID: 2458548
- Exp Neurobiol.
- 2019 Aug;28(4):504-515.
- doi: 10.5607/en.2019.28.4.504
Parkinson’s disease (PD) is one of the late-onset neurodegenerative movement disorder. Major pathological markers of PD include progressive loss of dopaminergic neurons, Lewy body formation, genetic mutations, and environmental factors.... -
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- Antiepileptic drug-induced severe cutaneous adverse reactions and HLA alleles: A report of five cases with lymphocyte activation test
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Kim EY, Kim MY, Park CS, Choi JH, Ghim JL, Kim HS, Shin JG
- KMID: 2457573
- Transl Clin Pharmacol.
- 2019 Jun;27(2):64-68.
- doi: 10.12793/tcp.2019.27.2.64
Antiepileptic drugs (AEDs) can induce severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. We... -
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- Dexmedetomidine and propofol sedation requirements in an autistic rat model
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Elmorsy SA, Soliman GF, Rashed LA, Elgendy H
- KMID: 2447512
- Korean J Anesthesiol.
- 2019 Apr;72(2):169-177.
- doi: 10.4097/kja.d.18.00005
BACKGROUND: Autism is a challenging neurodevelopmental disorder. Previous clinical observations have suggested altered sedation requirements for children with autism. Our study aimed to test this observation experimentally in an animal... -
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- Korean Medication Algorithm for Bipolar Disorder 2018: Comparisons with Other Treatment Guidelines
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Jeong JH, Bahk WM, Woo YS, Lee JG, Kim MD, Sohn I, Shim SH, Jon DI, Seo JS, Kim W, Song HR, Min KJ, Yoon BH
- KMID: 2456719
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):155-169.
- doi: 10.9758/cpn.2019.17.2.155
The objective of this study was to compare recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2018 (KMAP-BP 2018) with other recently published guidelines for treating bipolar disorder.... -
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- Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice
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Kee HJ, Ryu Y, Seok YM, Choi SY, Sun S, Kim GR, Jeong MH
- KMID: 2468620
- Clin Hypertens.
- 2019 ;25(1):13.
- doi: 10.1186/s40885-019-0118-8
BACKGROUND: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate... -
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- Valproate Is Contraindicated in POLG1 Mutations
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Finsterer
- KMID: 2430923
- Pediatr Gastroenterol Hepatol Nutr.
- 2019 Jan;22(1):105-106.
- doi: 10.5223/pghn.2019.22.1.105
No abstract available. -
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- Transient Abnormalities on Magnetic Resonance Imaging after Absence Seizures
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Yoo HW, Yoon L, Kim HY, Kwak MJ, Park KH, Bae MH, Lee Y, Nam SO, Kim YM
- KMID: 2437114
- J Korean Child Neurol Soc.
- 2018 Dec;26(4):280-283.
- doi: 10.26815/jkcns.2018.26.4.280
Magnetic resonance imaging (MRI) is recommended for patients with epileptic seizures to rule out an underlying focal lesion. However, abnormalities in idiopathic generalized epilepsy, including childhood absence epilepsy, cannot usually... -
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- Effects of Anticonvulsant Monotherapy on Bone Mineral Density in Children
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Shin C, Lee NY, Han JY, Yoo IH, Eom TH, Bin JH, Kim YH, Chung SY, Lee IG
- KMID: 2437111
- J Korean Child Neurol Soc.
- 2018 Dec;26(4):269-271.
- doi: 10.26815/jkcns.2018.26.4.269
PURPOSE: The use of anticonvulsants can cause side effects such as reduction of bone mineral density, requiring attention in growing children. The aim of our study is to investigate the... -
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- Antiepileptic and anti-neuroinflammatory effects of red ginseng in an intrahippocampal kainic acid model of temporal lobe epilepsy demonstrated by electroencephalography
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Kim JY, Kim JH, Lee HJ, Kim SH, Jung YJ, Lee HY, Kim HJ, Kim SY
- KMID: 2433738
- Yeungnam Univ J Med.
- 2018 Dec;35(2):192-198.
- doi: 10.12701/yujm.2018.35.2.192
BACKGROUND: Chronic inflammation can lower the seizure threshold and have influence on epileptogenesis. The components of red ginseng (RG) have anti-inflammatory effects. The abundance of peripherally derived immune cells in... -
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- Korean Medication Algorithm for Bipolar Disorder 2018 : Medical Comorbidity
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Song HR, Bahk WM, Yoon BH, Jon DI, Seo JS, Kim W, Lee JG, Woo YS, Jeong JH, Kim MD, Sohn I, Shim SH, Min KJ
- KMID: 2434869
- Mood Emot.
- 2018 Nov;16(3):129-133.
- doi: 10.0000/me.2018.16.3.129
OBJECTIVES: The fourth revision of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) was performed in 2018, to provide newer guidelines for clinicians. In this section, we examined expert opinions... -
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- Korean Medication Algorithm for Bipolar Disorder 2018 : Children and Adolescents
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Shim SH, Bahk WM, Yoon BH, Jon DI, Seo JS, Kim W, Lee JG, Woo YS, Jeong JH, Kim MD, Sohn I, Song HR, Min KJ
- KMID: 2434867
- Mood Emot.
- 2018 Nov;16(3):109-122.
- doi: 10.0000/me.2018.16.3.109
OBJECTIVES: The objective of this study was to revise the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) 2014: Children and Adolescents. METHODS: We performed the survey, using a questionnaire comprising... -
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- Dual mechanisms for the regulation of brain-derived neurotrophic factor by valproic acid in neural progenitor cells
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Ko HM, Jin Y, Park HH, Lee JH, Jung SH, Choi SY, Lee SH, Shin CY
- KMID: 2430090
- Korean J Physiol Pharmacol.
- 2018 Nov;22(6):679-688.
- doi: 10.4196/kjpp.2018.22.6.679
Autism spectrum disorders (ASDs) are neurodevelopmental disorders that share behavioral features, the results of numerous studies have suggested that the underlying causes of ASDs are multifactorial. Behavioral and/or neurobiological analyses... -
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- Clozapine-related Sudden Pericarditis in a Patient Taking Long Acting Aripiprazole and Valproate: A Case Report
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De Berardis D, Fornaro M, Orsolini L, Olivieri L, Nappi F, Rapini G, Vellante F, Napoletano C, Serroni N, Di Giannantonio M
- KMID: 2428982
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):505-507.
- doi: 10.9758/cpn.2018.16.4.505
Clozapine may be associated with cardiovascular adverse effects including QTc prolongation and, more rarely, with myocarditis and pericarditis. Although rare, these latter cardiovascular adverse effects may be life-threatening and must... -
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- Strategies of Using Antipsychotics in Patients with Bipolar Disorders
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Jeon HJ
- KMID: 2426858
- J Korean Neuropsychiatr Assoc.
- 2018 Nov;57(4):301-307.
- doi: 10.4306/jknpa.2018.57.4.301
Bipolar disorder is a recurrent chronic condition and patients usually continue long-term medication from young age to prevent the recurrence of mood episodes. Antipsychotics play an important role in acute... -
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- Effects of Valproic Acid on the Survival of Human Tennon's Capsule Fibroblasts
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Lee SE, Kim JW
- KMID: 2426367
- J Korean Ophthalmol Soc.
- 2018 Nov;59(11):1056-1061.
- doi: 10.3341/jkos.2018.59.11.1056
PURPOSE: To investigate the effects of valproic acid on the survival of cultured human Tenon's capsule fibroblasts (HTFBs). METHODS: Primary cultured HTFBs were exposed to 0, 0.25, 0.5, and 1.0 mM... -
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