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Meningococcal Vaccines

Lee SO

  • KMID: 1482511
  • Hanyang Med Rev.
  • 2008 Aug;28(3):70-76.
Meningococcal polysaccharide vaccines did not elicit a memory response; they induced a response that was neither long-lasting nor anamnestic after subsequent challenges with the same polysaccharide antigen. Conjugate vaccines developed...
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Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines

Lee H, Choi EH, Lee HJ

The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of...
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Present status and prospects of Haemophilus influenzae type b(Hib) immunization

Kim KH

Haemophilus influenzae type b(Hib) conjugate vaccines prevent Hib disease in individuals and reduce the carriage and transmission of the organism in the community. The incidence of Hib disease has been...
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Indirect Effects of Pneumococcal Conjugate Vaccines in National Immunization Programs for Children on Adult Pneumococcal Disease

Kim YK, LaFon D, Nahm MH

The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have...
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Disease Burden and Etiologic Distribution of Community-Acquired Pneumonia in Adults: Evolving Epidemiology in the Era of Pneumococcal Conjugate Vaccines

Heo JY, Song JY

Pneumonia is the leading cause of morbidity and mortality, particularly in old adults. The incidence and etiologic distribution of community-acquired pneumonia is variable both geographically and temporally, and epidemiology might...
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Comparison of Immune Responses to Two Quadrivalent Meningococcal Conjugate Vaccines (CRM197 and Diphtheria Toxoid) in Healthy Adults

Kim HW, Lee S, Lee JH, Woo SY, Kim KH

BACKGROUND: After the introduction of the meningococcal ACWY-CRM197 conjugate vaccine (MenACWY-CRM) in 2012 and the meningococcal ACWY-diphtheria toxoid conjugate vaccine (MenACWY-DT) in 2014, immunization was recommended for certain high-risk groups...
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Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea

Choi EH, Kim KH, Kim YJ, Kim JH, Park SE, Lee HJ, Eun BW, Jo DS, Choi KM, Hong YJ

Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults. The 7-valent...
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Immunogenicity of Haemophilus influenzae Type b Conjugate Vaccines in Korean Infants: A Meta-analysis

Lee H, Hahn S, Lee HJ, Kim KH

A meta-analysis was performed on the immunogenicity of Haemophilus influenzae type b (Hib) conjugate vaccines after 2 (2 and 4 months) and 3 doses (2, 4, and 6 months) in...
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A case of fatal pneumococcal 19A meningoencephalitis despite administration of seven-valent pneumococcal conjugate vaccines

Heo AR, Lee JH

Streptococcus pneumoniae is a major cause of serious invasive diseases in children, especially in young infants, but seven-valent pneumococcal conjugate vaccine (PCV7) is believed to prevent invasive pneumococcal pneumonia and...
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Status of group B streptococcal vaccine development

Lin SM, Zhi Y, Ahn KB, Lim S, Seo HS

Streptococcus agalactiae (group B streptococcus, GBS) is a leading causal organism of neonatal invasive diseases and severe infections in the elderly. Despite significant advances in the diagnosis and treatment of...
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Recommended immunization schedule for children and adolescents: Immunization Guideline (8th edition) released by the Korean Pediatric Society in 2015

Kim JH, Choi EH, Park SE, Kim YJ, Jo DS, Kim YK, Eun BW, Lee J, Lee SY, Lee H, Kim KH, Kim KH

This report includes the recommended immunization schedule table for children and adolescents based on the 8th (2015) and revised 7th (2012) Immunization Guidelines released by the Committee on Infectious Diseases...
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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine

Cha J, Kim HW, Lee JH, Lee S, Kim KH

BACKGROUND: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to...
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Inhibition of Allergic Response by CpG Motif Immunostimulatory Oligodeoxynucleotide Conjugate in Murine Model of Allergic Rhinitis

Lee CH, Mo JH, Lee SS, Quan SH, Park JL, Wang SY, Kim IS, Shim WS, Rhee HS

  • KMID: 2276461
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Aug;48(8):991-997.
BACKGROUND AND OBJECTIVES: Recently, the incidence of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis is on the increase with the society getting more and more industrialized. Although...
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Changes in Serotype Distribution and Antibiotic Resistance of Nasopharyngeal Isolates of Streptococcus pneumoniae from Children in Korea, after Optional Use of the 7-Valent Conjugate Vaccine

Cho EY, Kang HM, Lee J, Kang JH, Choi EH, Lee HJ

We investigated serotype distribution and antimicrobial resistance of pneumococcal carriage isolates from children after optional immunization with the 7-valent pneumococcal conjugate vaccine (PCV7) in Korea. From June 2009 to June...
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Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine

Lee JK, Yun KW, Choi EH, Kim SJ, Lee SY, Lee HJ

This study investigated the serotype distribution and antimicrobial resistance of 3,820 nasopharyngeal Streptococcus pneumoniae isolates from infants and children who presented with respiratory symptoms at Seoul National University Children's Hospital...
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The Evolving Epidemiology of Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Strains Isolated from Adults in Crete, Greece, 2009–2016

Maraki S, Mavromanolaki VE, Stafylaki , Hamilos G, Samonis G

BACKGROUND: Pneumococcal disease is a major cause of morbidity and mortality worldwide, especially in patients with comorbidities and advanced age. This study evaluated trends in epidemiology of adult pneumococcal disease...
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Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience

Lee J, Kwon H, Lee JS, Kim HD, Kang HC

PURPOSE: The widespread introduction of bacterial conjugate vaccines has decreased the risk of cerebrospinal fluid (CSF) pleocytosis due to bacterial meningitis (BM) in children. However, most patients with CSF pleocytosis...
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A Study on the Discourse and Reality of Abortion in Korea: 1920s~1930s

Lee YA

  • KMID: 2129219
  • Korean J Med Hist.
  • 2013 Apr;22(1):133-178.
This paper tried to collect, classify and analyse the discourse about abortion in 1920~1930. In Korea, modern medical abortion operation started in 1920~30s. At that time abortion was prohibited by...
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Immunogenicity of MenACWY-CRM in Korean Military Recruits: Influence of Tetanus-Diphtheria Toxoid Vaccination on the Vaccine Response to MenACWY-CRM

Kim HW, Park IH, You S, Yu HT, Oh IS, Sung PS, Shin EC, Kim KH

The quadrivalent meningococcal conjugate vaccine (MenACWY-CRM) has been introduced for military recruits in Korea since 2012. This study was performed to evaluate the immunogenicity of MenACWY-CRM in Korean military recruits....
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