- Uracil-DNA glycosylase-treated reverse transcription loop-mediated isothermal amplification for rapid detection of avian influenza virus preventing carry-over contamination
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Kim EM, Jeon HS, Kim JJ, Shin YK, Lee YJ, Yeo SG, Park CK
- KMID: 2413144
- J Vet Sci.
- 2016 Sep;17(3):421-425.
- doi: 10.4142/jvs.2016.17.3.421
Here, we describe a uracil-DNA glycosylase (UNG)-treated reverse transcription loop-mediated isothermal amplification (uRT-LAMP) for the visual detection of all subtypes of avian influenza A virus (AIV). The uRT-LAMP assay can... -
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- Volume-reserving Surgery after Photodynamic Therapy for Biliary Papillomatosis: A Case Report
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Cheong CO, Lim JH, Park JS, Park SW, Kim HK, Kim KS
- KMID: 2373313
- Korean J Gastroenterol.
- 2015 Jul;66(1):55-58.
- doi: 10.4166/kjg.2015.66.1.55
Biliary papillomatosis is rare, and its pathogenic mechanisms are not yet clear. Because of its high risk for malignancy transformation, surgical resection is regarded as a standard treatment. Photodynamic therapy... -
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- High-dose oral tegafur-uracil maintenance therapy in patients with uterine cervical cancer
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Sakaguchi , Motohara T, Saito F, Takaishi K, Fukumatsu , Tohya T, Shibata S, Mimori H, Tashiro H, Katabuchi
- KMID: 2160805
- J Gynecol Oncol.
- 2015 Jul;26(3):193-200.
- doi: 10.3802/jgo.2015.26.3.193
OBJECTIVE: The aim of this study was to determine the efficacy and toxicity of oral administration of tegafur-uracil (UFT) at a high dose, 600 mg/day, based on the tegafur dose,... -
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- Comparison of DPP-4 Inhibitors
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Kim NH, Kim SG
- KMID: 2173918
- J Korean Diabetes.
- 2013 Sep;14(3):111-119.
- doi: 10.4093/jkd.2013.14.3.111
During past several years, a novel class of antihyperglycemic agents, dipeptidyl peptidase-4 (DPP-4) inhibitors, has become one of the most important options in the management of type 2 diabetes. These... -
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- Clinical predictive factors of pathologic tumor response after preoperative chemoradiotherapy in rectal cancer
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Choi CH, Kim WD, Lee SJ, Park WY
- KMID: 2316706
- Radiat Oncol J.
- 2012 Sep;30(3):99-107.
PURPOSE: The aim of this study was to identify clinical predictive factors for tumor response after preoperative chemoradiotherapy (CRT) in rectal cancer. MATERIALS AND METHODS: The study involved 51 patients who... -
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- Discoid Lupus Erythematosus-like Eruption Induced by Tegafur - Uracil (UFT)
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Yoon J, Seo SH, Kye YC, Ahn HH
- KMID: 2301813
- Korean J Dermatol.
- 2010 Nov;48(11):1004-1007.
The second-generation oral anticancer agent UFT is a combination of uracil, which has fluorouracil's (5-FU) degradation-inhibitory effect, and tegafur, which is slowly converted to 5-FU in vivo, and UFT shows... -
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- A Case of Fixed Drug Eruption Induced by Tegafur-Uracil(TEGASIL)
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Heo YS, Song HJ, Oh CH
- KMID: 2247720
- Korean J Dermatol.
- 2010 Feb;48(2):155-157.
A mixture of tegafur and uracil (TEGASIL) is a common antineoplastic agent. Tegafur is a fluoropyrimidine structurally similar to 5-fluorouracil (5-FU); uracil slows the degradation of 5-FU by dihydropyrimidine dehydrogenase,... -
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- Chemical Constituents of the Fruiting Bodies of Clitocybe nebularis and Their Antifungal Activity
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Kim YS, Lee IK, Seok SJ, Yun BS
- KMID: 2411406
- Mycobiology.
- 2008 Jun;36(2):110-113.
During a continuing search for antimicrobial substances from Korean native wild mushroom extracts, we found that the methanolic extract of the fruiting body of Clitocybe nebularis exhibited mild antifungal activity... -
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- Small Animal PET Imaging with [124I]FIAU for Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression in a Hepatoma Model
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Chae MJ, Lee TS, Kim JY, Woo GS, Jumg WS, Chun KS, Kim JH, Lee JS, Ryu JS, Cheon GJ, Choi CW, Lim SM
- KMID: 2313046
- Nucl Med Mol Imaging.
- 2008 Jun;42(3):235-234.
PURPOSE: The HSV1-tk gene has been extensively studied as a type of reporter gene. In hepatocellular carcinoma (HCC), only a small proportion of patients are eligible for surgical resection and... -
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- Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats
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Chae KA, Cho HJ, Sung JM, Lee H, Seo DC, Kim JS, Shin HC
- KMID: 1090801
- J Vet Sci.
- 2007 Sep;8(3):263-267.
- doi: 10.4142/jvs.2007.8.3.263
The primary objective of this study was to compare thepharmacokinetics of a new anti-human immunodeficiencyvirus agent 1-(2-amino-pyridin-4-ylmethyl)-6-(3,5-dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione (VP-0502)with its amino acid prodrug alanine amide of VP-0502(VP-0502AL), following intravenous and oral... -
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- DNA methylation of Bcl-2 family genes in cancer cells
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Kang Y, Lee SY, Jung SG, Han J, Ko JJ, Bae J, Na YJ, Lee C, Mock JU, Kim SJ, Hwang YY
- KMID: 2273147
- Korean J Obstet Gynecol.
- 2007 Jul;50(7):997-1002.
OBJECTIVE: Promoter methylation of Bcl-2 family genes in cancer cells were studied to verify possible correlation between DNA methylation pattern of Bcl-2 family members and cancer. METHODS: The genomic DNAs... -
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- A Case of 5-fluorouracil-induced Phototoxicity
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Cho EA, Kim SY
- KMID: 2087201
- Korean J Dermatol.
- 2006 Nov;44(11):1364-1366.
5-fluorouracil (5-FU) is an antimetabolite which prevents thymine synthesis and suppresses the utilization of preformed uracil. A variety of cutaneous reactions have been reported with the use of systemic 5-FU,... -
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- Postoperative Adjuvant Chemoradiotherapy in Rectal Cancer
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Chang SK, Kim JW, Oh D, Chong SY, Shin HS
- KMID: 1512291
- J Korean Soc Ther Radiol Oncol.
- 2006 Sep;24(3):157-163.
PURPOSE: To evaluate the role of postoperative adjuvant chemoradiotherapy in rectal cancer, we retrospectively analyzed the treatment outcome of patients with rectal cancer taken curative surgical resection and postoperative adjuvant... -
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- Lesch-Nyhan syndrome and purine and pyrimidine metabolism didorders
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Kim SZ
- KMID: 2168076
- Hanyang Med Rev.
- 2005 Aug;25(3):92-101.
Purine & pyrimidine nucleotides are basic constituents of cellular DNA and RNA polynucleotides. Their function includes regulation of cell metabolism and function, energy conservation and transport and formation of coenzymes... -
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- Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms in Colorectal Cancer
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Park WC, Lee JK
- KMID: 1606360
- J Korean Soc Coloproctol.
- 2005 Aug;21(4):241-246.
PURPOSE: Recently, the role of vitamins, folate in particular, has been emphasized in the maintenance of health. Folate deficiency is known to give rise to developmental delay, pre-mature vascular disease,... -
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- Methylenetetrahydrofolate Reductase C677T Polymorphism in Gastric Cancer
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Seo W, Park WC, Lee JK, Kim JJ
- KMID: 2372764
- J Korean Gastric Cancer Assoc.
- 2005 Mar;5(1):10-15.
PURPOSE: Recently the role of vitamins, folate in particular, has been emphasized in the maintenance of health. Folate deficiency is known to give rise to developmental delay, immature vascular disease,... -
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- Oxaliplatin and UFT, leucovorin combination chemotherapy in patients with advanced colorectal cancer
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Shin JH, Kim SY, Woo CM, Kim YS, Kim JY, Seo JH, Lee WS, Bae SH, Ryoo HM, Lee HI, Shin IH, Kim MK, Lee JL, Lee KH, Hyun MS
- KMID: 2252594
- Korean J Med.
- 2004 Jul;67(1):58-64.
BACKGROUND: UFT/oral leucovorin (LV) provided a safer, more convenient oral alternative to bolus i.v. 5-Fluorouracil/LV regimen for advanced colorectal cancer while producing equivalent survival. We evaluated the efficacy and safety... -
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- Oral Tegafur-uracil Plus Folinic Acid versus Intravenous 5-fluorouracil Plus Folinic Acid as Adjuvant Chemotherapy of Colon Cancer
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Kim DJ, Kim TI, Suh JH, Cho YS, Shin SK, Kang JK, Kim NK, Kim WH
- KMID: 720907
- Yonsei Med J.
- 2003 Aug;44(4):665-675.
- doi: 10.3349/ymj.2003.44.4.665
To compare, in terms of compliance, toxicity, quality of life (QOL) and efficacy, intravenous 5-fluorouracil plus folinic acid with oral tegafur-uracil plus folinic acid as postoperative adjuvant chemotherapy after curative... -
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- Clinical Pharmacokinetics of Tegafur Administered with Epirubicin and Cisplatin in Patients with Advanced Gastric Cancer
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Kang JH, Kim YL, Cho HK, Lee ES, Cha SJ, Hong YS, Lee KS, Kuh HJ
- KMID: 2166181
- Cancer Res Treat.
- 2003 Jun;35(3):224-231.
PURPOSE: Tegafur, an oral prodrug of 5-fluorouracil (5-FU), has been used in the treatment of gastric cancers. UFT (tegafur + uracil) has been developed to enhance the efficacy of tegafur.... -
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- The Efficient Transformation of Pleurotus ostreatus using REMI Method
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Joh JH, Kim BG, Chu KS, Kong WS, Yoo YB, Lee CS
- KMID: 2052977
- Mycobiology.
- 2003 Mar;31(1):32-35.
- doi: 10.4489/MYCO.2003.31.1.032
Restriction enzyme-mediated integration (REMI) was used to transform uracil auxotrophs of Pleurotus ostreatus to prototrophy. When protoplasts of Pleurotus ostreatus were treated by the reaction mixture containing 10 units of... -
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