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An open clinical trial on the effectiveness of trimebutine maleate (polybutine) in the irritable bowel syndrome: a comparative study of dosing twice and three times a day

Kim YK, Kim HJ, Chang R

  • KMID: 1772344
  • Korean J Gastroenterol.
  • 1993 Jun;25(3):473-478.
No abstract available.
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A clinical assessment on the effectiveness of trimebutine meleate(polybutine) in the irritable bowel syndrome

Lee S, Yoon SJ, Ham JS, Lee JC, Lee MH, Lee DH, Ki CS, Park KN

  • KMID: 2240746
  • Korean J Gastroenterol.
  • 1993 Dec;25(6):1156-1162.
No abstract available.
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The Effect of Trimebutine on the Overlap Syndrome Model of Guinea Pigs

Hussain Z, Jung DH, Lee YJ, Park H

  • KMID: 2422856
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):669-675.
  • doi: 10.5056/jnm18049
BACKGROUND/AIMS: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) disorders and these patients frequently overlap. Trimebutine has been known to be effective in controlling FD co-existing...
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The Effect of Trimebutine and/or Helicobacter pylori Eradication on the Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Dyspepsia Overlapping Disorders

Kountouras J, Gavalas E, Doulberis , Polyzos SA, Papaefthymiou A, Touloumtzi M, Vardaka E, Kountouras K, Papanikolopoulou K, Katsinelos P

  • KMID: 2454646
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):473-474.
  • doi: 10.5056/jnm19033
No abstract available.
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The Incidence of Irritable Bowel Syndrome in Children Using the Rome III Criteria and the Effect of Trimebutine Treatment

Karabulut , Beser OF, Erginoz E, Kutlu T, Cokugras F, Erkan T

  • KMID: 2325977
  • J Neurogastroenterol Motil.
  • 2013 Jan;19(1):90-93.
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders and when compared to the vast knowledge pertaining to adults with IBS, very little is known...
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A Clinical Trial of Polybutine Syrup to Pediatric G-I Symptomes

Moon IS, Ro KS, Lee IJ, Lee DB

  • KMID: 1699576
  • J Korean Pediatr Soc.
  • 1982 Jan;25(1):41-44.
This clinical trial was undertaken on 32 infants and chhildren who had G-I symptoms caused by a few diseases, such as meningitis, parenteral infection and intestinal infection. Out of 32...
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Efficacy of Fenoverine and Trimebutine in the Management of Irritable Bowel Syndrome: Multicenter Randomized Double-blind Non-inferiority Clinical Study

Kang SH, Jeen YT, Koo JS, Koo YS, Kim KO, Kim YS, Kim SY, Moon JS, Park JJ, Baek IH, Park SC, Lee SJ, Lee JH, Choung RS, Choi SC

BACKGROUND/AIMS: Antispasmodic agents have been used in the management of irritable bowel syndrome. However, systematic reviews have come to different conclusions about the efficacy in irritable bowel syndrome. Fenoverine acts...
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Effect of antispasmodic agents for the treatment of irritable bowel syndrome

Lee SH, Jee SR

Antispasmodics are effective in reducing abdominal pain and controlling spasm. Irritable bowel syndrome (IBS) patients have characteristic key factors such as intestinal motility disorder and visceral hypersensitivity. So antispasmodics have...
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