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Role of neuron and non-neuronal cell communication in persistent orofacial pain

Iwata K, Shinoda M

It is well known that trigeminal nerve injury causes hyperexcitability in trigeminal ganglion neurons, which become sensitized. Long after trigeminal nerve damage, trigeminal spinal subnucleus caudalis and upper cervical spinal...
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Trigeminal Neuralgia Resulting from Delayed Cervical Cord Compression after Acute Traumatic Fracture of Odontoid Process

Shim YW, Paeng SH, Lee KS, Kim ST, Lee WH

Trigeminal neuralgia is caused by compression of trigeminal nerve root and it leads to demyelination gradually. It was almost idiopathic and occurred unexpected. The upper cervical spinal cord contains the...
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Effect of carbamazepine on tetrodotoxin-resistant Na⁺ channels in trigeminal ganglion neurons innervating to the dura

Han JE, Cho JH, Nakamura M, Lee MG, Jang IS

Migraine is a neurological disorder characterized by recurrent and disabling severe headaches. Although several anticonvulsant drugs that block voltage-dependent Na⁺ channels are widely used for migraine, far less is known...
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Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats

Yoon JH, Son JY, Kim MJ, Kang SH, Ju JS, Bae YC, Ahn DK

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male...
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Incidence of pterygospinous and pterygoalar bridges in dried skulls of Koreans

Ryu SJ, Park MK, Lee UY, Kwak HH

Understanding of morphological structures such as the sphenoid spine and pterygoid processes is important during lateral transzygomatic infratemporal fossa approach. In addition, osseous variations such as pterygospinous and pterygoalar bridges...
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Morphological Analysis of the Myelinated Parent Axons that Innervate Rat Upper Molar Pulps in the Trigeminal Ganglion

Paik SK, Kim JH, Kim TH, Bae YC

Previous studies suggested that myelinated axons innervating rat molar pulps undergo morphological changes in their peripheral course. However, little information is available on the morphological feature of the parent axons...
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Involvement of Endoplasmic Reticulum Stress Response in Orofacial Inflammatory Pain

Yang ES, Bae JY, Kim TH, Kim YS, Suk K, Bae YC

Endoplasmic reticulum (ER) stress is involved in many neurological diseases and inflammatory responses. Inflammatory mediators induce neuronal damage and trigger the neuropathic or inflammatory pain. But there is very little...
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Trigemino-cardiac reflex: occurrence of asystole during trans-sphenoidal adenomectomy: a case report

Jeon DG, Kang BJ, Hur TW

The trigemino-cardiac reflex has been reported to occur during various craniofacial surgeries or procedures including manipulation of the trigeminal ganglion, tumor resection in the cerebellopontine angle, various facial reconstructions and...
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Experience with Conventional Radiofrequency Thermorhizotomy in Patients with Failed Medical Management for Trigeminal Neuralgia

Singh S, Verma R, Kumar M, Rastogi V, Bogra J

BACKGROUND: To evaluate the results of conventional radiofrequency thermorhizotomy (CRT) for trigeminal neuralgia (TN) in patients with failed medical management. METHODS: Patients with Trigeminal neuralgia who were referred to us for...
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Petrositis With Bilateral Abducens Nerve Palsies complicated by Acute Otitis Media

Choi KY, Park SK

  • KMID: 2278409
  • Clin Exp Otorhinolaryngol.
  • 2014 Mar;7(1):59-62.
Petrous apicitis is a rare but fatal complication of otitis media. An infection within the middle ear can extend within the temporal bone into the air cells of the petrous...
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Expression of Deleted in Colorectal Cancer in the Rat Trigeminal Ganglia

Lee EJ, Kim NR, Yoo HI, Yang SY, Kang JH, Kim HJ, Kim MS, Kim SH

  • KMID: 1431129
  • Int J Oral Biol.
  • 2012 Dec;37(4):161-166.
The deleted in colorectal cancer (DCC) protein mediates attractant responses to netrin during axonogenesis. In the rat trigeminal ganglia (TG), axons must extend toward and grow into the trigeminal nerve...
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Neurochemical Properties of Dental Primary Afferent Neurons

Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB

The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among...
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Alteration of LAR-RPTP Expression in the Rat Trigeminal Ganglion after Tooth Extraction

Kim SH, Kim HJ

  • KMID: 1445157
  • Int J Oral Biol.
  • 2011 Dec;36(4):167-172.
LAR-RPTP (leukocyte common antigen-related receptor protein tyrosine phosphatase) is an important regulator in the nervous system, but little is known about its expression pattern in rat trigeminal ganglion (TG) neurons....
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Trigeminal Neuralgia and Neural Blockade

Shin KM

Trigeminal neuralgia is characterized by recurrent episodes of intense lancinating pain affecting the face localized to the sensory supply areas of the trigeminal nerve. There is a lack of certainty...
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A Clinical Study on Herpes Zoster Meningoencephalitis

Byun JW, Song HJ, Choi GS, Shin JH

  • KMID: 2247587
  • Korean J Dermatol.
  • 2011 Apr;49(4):328-333.
BACKGROUND: Herpes zoster meningoencephalitis is a rare neurological complication and the known risk factors include an immunocompromised status, infiltration into the trigeminal ganglion, disseminated herpes zoster and elderly patients. Serious...
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Infrared-sensitive pit organ and trigeminal ganglion in the crotaline snakes

Moon C

The infrared (IR) receptors in the pit organ of crotaline snakes are very sensitive to temperature. The sensitivity to IR radiation is much greater in crotaline snakes than in boid...
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The Intracisternal Administration of MEK Inhibitor Attenuates Mechanical and Cold Allodynia in a Rat Model of Compression of the Trigeminal Ganglion

Lee MK, Yoon JH, Park MK, Yang GY, Won KA, Park YY, Ahn DK

  • KMID: 1457179
  • Int J Oral Biol.
  • 2010 Sep;35(3):75-81.
The present study investigated the role of ERK in the onset of mechanical and cold allodynia in a rat model of compression of the trigeminal ganglion by examining changes in...
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R-type Calcium Channel Isoform in Rat Dorsal Root Ganglion Neurons

Fang Z, Hwang JH, Kim JS, Jung SJ, Oh SB

R-type Cav2.3 high voltage-activated Ca2+ channels in peripheral sensory neurons contribute to pain transmission. Recently we have demonstrated that, among the six Cav2.3 isoforms (Cav2.3a~Cav2.3e), the Cav2.3e isoform is primarily...
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Pulsed Radiofrequency Treatment of the Supraorbital and Supratrochlear Nerve in a Case of Trigeminal Neuralgia: A case report

Seo KC, Shin HD, Kim JH, Song SY, Rho WS, Chung JY

Pharmacological management is the first choice for treatment of the trigeminal neuralgia patients; however, if this mode of treatment fails a minimally invasive procedure should be performed. One of the...
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Anesthetic management of percutaneous balloon compression of the trigeminal ganglion for the treatment of trigeminal neuralgia: Two cases report

Kim HT, An SK, Jang IS, Kim HI

Trigeminal neuralgia is sudden, usually unilateral, severe brief stabbing recurrent pain in the distribution of one or more branches of the 5th cranial nerve. Treatments of trigeminal neuralgia include systemic...
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