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Regional clinical pharmacology trials for Multi-Regional clinical trials

Jang IJ

No abstract available.
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Erratum: Comparison of various estimation methods for the parameters of Michaelis-Menten equation based on in vitro elimination kinetic simulation data

Cho YS, Lim HS

There are some errors in the published article. The authors would like to make corrections in the original version of the article.
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Erratum: Population Pharmacokinetic Analysis of Metformin Administered as Fixed-Dose Combination in Korean Healthy Adults

Choi S, Jeon S, Han S, Yim DS

In the published version of this article, the contents of Table 1 (‘Demographic characteristics of subjects’) are incorrect.
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Erratum: Development of R packages: ‘NonCompart’ and ‘ncar’ for noncompartmental analysis (NCA)

Kim H, Han S, Cho YS, Yoon SK, Bae KS

There are some errors in the published article. The authors would like to make corrections in the original version of the article.
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Mechanistic ligand-receptor interaction model: operational model of agonism

Kim H, Lim HS

This tutorial explains the basic principles of mechanistic ligand-receptor interaction model, which is an operational model of agonism. A growing number of agonist drugs, especially immune oncology drugs, is currently...
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Augmented renal clearance

Atkinson A

Adding to the complexity of caring for critically ill patients is the fact that many of them have a creatinine clearance that exceeds 130 mL/min/1.73 m². This phenomenon, termed augmented...
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Survey on the undergraduate curriculum in clinical pharmacology and interns' prescribing ability in South Korea

Gu N, Kim KJ, Lim CY, Lee JK, Rhee MY, Shin KH, Lee SH, Ahn S

Appropriate prescription writing is one of the critical medical processes affecting the quality of public health care. However, this is a complex task for newly qualified intern doctors because of...
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Microbe-derived extracellular vesicles as a smart drug delivery system

Yang J, Kim EK, McDowell A, Kim YK

The human microbiome is known to play an essential role in influencing host health. Extracellular vesicles (EVs) have also been reported to act on a variety of signaling pathways, distally...
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Development of a UPLC-MS/MS method for the therapeutic monitoring of L-asparaginase

Jeong HC, Kim T, Yang DH, Shin KH

This study aimed to develop a UPLC-MS/MS method for determining plasma levels of L-aspartic acid and L-asparagine and the activity of L-asparaginase. L-aspartic acid, L-asparagine, and L-aspartic acid-2,3,3-d3 were extracted...
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Safety and efficacy of fimasartan with essential hypertension patients in real world clinical practice: data from a post marketing surveillance in Korea

Han SE, Jeong SH, Kang HJ, Hong MS, Paek E, Cho H, Choe SC

The safety and efficacy of fimasartan have been evaluated through post-marketing surveillance in real world clinical practice. The multi-center, prospective, open-label and non-interventional study. A total of 3,945 patients (3,729...
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