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Decreased expression of Toll-like receptor 4 and 5 during progression of prostate transformation in transgenic adenocarcinoma of mouse prostate mice

Han JH, Park JH, Kim BY, Chang SN, Kim TH, Park JH, Kim DJ

Chronic inflammation has been considered an important risk factor for development of prostate cancer. Toll-like receptors (TLRs) recognize microbial moieties or endogenous molecules and play an important role in the...
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Association of Toll-Like Receptor Gene with Crohn's Disease in Koreans

Ye BD, Yang SK, Song K, Yang DH, Yoon SM, Kim KJ, Byeon JS, Myung SJ, Kim JH

BACKGROUND/AIMS: Toll-like receptors (TLRs) serve as pattern recognition receptors that recognize specific molecular patterns of pathogens and can mediate the production of proinflammatory cytokines. Recently, TLRs have been identified as...
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Rarity of TLR4 Asp299Gly and Thr399Ile Polymorphisms in the Korean Population

Kim YS, Hwang YJ, Kim SY, Yang SM, Lee KY, Park IB

  • KMID: 2396087
  • Yonsei Med J.
  • 2008 Feb;49(1):58-62.
PURPOSE: Activation of the innate immune system and chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and also thought to be associated with type 2...
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Association between Recent Acetaminophen Use and Asthma: Modification by Polymorphism at TLR4

Lee SH, Kang MJ, Yu HS, Hong K, Jung YH, Kim HY, Seo JH, Kwon JW, Kim BJ, Kim HJ, Kim YJ, Kim HS, Kim HB, Park KS, Lee SY, Hong SJ

The risk of asthma has been increasing in parallel with use of acetaminophen, which is a potential source of oxidative stress. Toll-like receptor 4 (TLR4) plays a critical role not...
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