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Hyperosmotic Stimulus Down-regulates 1alpha, 25-dihydroxyvitamin D3-induced Osteoclastogenesis by Suppressing the RANKL Expression in a Co-culture System

Tian YS, Jeong HJ, Lee SD, Kong SH, Ohk SH, Yoo YJ, Seo JT, Shin DM, Sohn BW, Lee SI

The hyperosmotic stimulus is regarded as a mechanical factor for bone remodeling. However, whether the hyperosmotic stimulus affects 1alpha, 25-dihydroxyvitamin D3 (1alpha,25(OH)2D3)-induced osteoclastogenesis is not clear. In the present study,...
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The effect of progressive tensional force on mRNA expression of osteoprotegerin and receptor activator of nuclear factor kappa B ligand in the human periodontal ligament cell

Lee KJ, Lee SI, Hwang CJ, Ohk SH, Tian YS

  • KMID: 1762553
  • Korean J Orthod.
  • 2005 Aug;35(4):262-274.
Tooth movement is a result of mutual physiologic responses between the periodontal ligament and alveolar bone stimulated by mechanical strain. The PDL cell and osteoblast are known to have an...
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