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Clevudine induced diabetes mellitus in a patient with chronic hepatitis B

Kim GW, Lee MY, Kim SY, Kim JH, Lee JH, Chung CH

  • KMID: 1458437
  • Korean J Med.
  • 2010 Nov;79(5):569-572.
Several studies have documented that various agents can induce diabetes mellitus, such as steroids, thiazides, anti-psychotic agents, and anti-viral agents. Many antiviral agents are also reported to impair insulin resistance...
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Rheumatoid arthritis accompanied by Gitelman syndrome

Park MG, Lee JH, Kim SJ, Park SH, Park SK, Choi JS, Hwang JY

Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including...
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Two cases of hypokalemic rhabdomyolysis due to thiazide treatment

Shin SH, Sun DS, Kim G, Kim YS, Yoon SA, Chang YS, Kim YO

  • KMID: 2256482
  • Korean J Med.
  • 2007 Jan;72(1):100-104.
Hypokalemia is a common metabolic cause of rhabdomyolysis. Although treatment with thiazide causes hypokalemia frequently, hypokalemic rhabdomyolysis after administration with thiazide is very rare. Here we report two cases of...
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Thiazide-Induced Hyponatremia

Hwang KS, Kim GH

The importance of thiazide-induced hyponatremia (TIH) is reemerging because thiazide diuretic prescription seems to be increasing after the guidelines recommending thiazides as first-line treatment of essential hypertension have been introduced....
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Clinical Studies on the Hypotensive Effect of Non-Thiazide Diuretics, Sulfamoyl Benzamide

Kim SG, Lim HK, Lee BH, Lee CK

Thizide diuretics which are widely used nowadays, are considered to be drugs of first choice of antihypertensive agents, due to their slow and useful diuretic effects in hypertensive patients. But...
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The Effects of Antihypertensive Drugs on Bone Mineral Density in Ovariectomized Mice

Kang KY, Kang Y, Kim M, Kim Y, Yi H, Kim J, Jung HR, Park SH, Kim HY, Ju JH, Hong YS

The effects of several antihypertensive drugs on bone mineral density (BMD) and micro-architectural changes in ovariectomized (OVX) mice were investigated. Eight-week-old female C57/BL6 mice were used for this study. Three...
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The Changes of Aquaporin-2 Expression in Rats with Lithium Induced Nephrogenic Diabetes Insipidus after Hydrochlorothiazide Administration

Oh YK, Lee JW, Chang HR, Park YS, Kim GH, Han JS, Earm JH

  • KMID: 1989561
  • Korean J Nephrol.
  • 2004 Jan;23(1):5-11.
BACKGROUND: Thiazides have been used in nephrogenic diabetes insipidus (NDI) patients to decrease urine volume, but the mechanism of antidiuretic effect is not known yet. Recently, it has been demonstrated...
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Effects of Thiazide on the Expression of TRPV5, Calbindin-D28K, and Sodium Transporters in Hypercalciuric Rats

Jang HR, Kim S, Heo NJ, Lee JH, Kim HS, Nielsen S, Jeon US, Oh YK, Na KY, Joo KW, Han JS

TRPV5 is believed to play an important role in the regulation of urinary calcium excretion. We assessed the effects of hydrochlorothiazide (HCTZ) on the expression of TRPV5, calbindin-D28K, and several...
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