- Mad2B forms a complex with Cdc20, Cdc27, Rev3 and Rev1 in response to cisplatin-induced DNA damage
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Kim JH, Patel R
- KMID: 2545533
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):427-436.
- doi: 10.4196/kjpp.2023.27.5.427
Mitotic arrest deficient 2 like 2 (Mad2L2, also known as Mad2B), the human homologue of the yeast Rev7 protein, is a regulatory subunit of DNA polymerase ζ that shares high... -
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- Kinesin superfamily member 15 knockdown inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma
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Cai Y, Lai Q, Zhang X, Zhang Y, Zhang M, Gu S, Qin Y, Hou J, Zhao L
- KMID: 2545536
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):457-470.
- doi: 10.4196/kjpp.2023.27.5.457
The aim of this study was to investigate the role of kinesin superfamily member 15 (KIF15) in nasopharyngeal carcinogenesis (NPC) and explore its underlying mechanisms. We employed various assays, including... -
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- Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis
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Meng RY, Li CS, Hu D, Kwon SG, Jin H, Chai OH, Lee JS, Kim SM
- KMID: 2545539
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):493-511.
- doi: 10.4196/kjpp.2023.27.5.493
Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in esophageal... -
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- Peptides derived from high voltage-gated calcium channel ββ subunit reduce blood pressure in rats
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Kim HK, Jun J, Kim TW, Youn Dh
- KMID: 2545538
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):481-491.
- doi: 10.4196/kjpp.2023.27.5.481
The β subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal channel functions such as channel gating, activation-inactivation kinetics, and trafficking to the membrane. In this study, we... -
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- N-retinylidene-N-retinylethanolamine degradation in human retinal pigment epithelial cells via memantine- and ifenprodil-mediated autophagy
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Lee JR, Jeong KW
- KMID: 2545535
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):449-456.
- doi: 10.4196/kjpp.2023.27.5.449
N-methyl-D-aspartate (NMDA) receptors are ionic glutamine receptors involved in brain development and functions such as learning and memory formation. NMDA receptor inhibition is associated with autophagy activation. In this study,... -
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- Dendritic cells resist to disulfiram-induced cytotoxicity, but reduced interleukin-12/23(p40) production
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Jung H, Joo HG
- KMID: 2545537
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):471-479.
- doi: 10.4196/kjpp.2023.27.5.471
Disulfiram (DSF), a medication for alcoholism, has recently been used as a repurposing drug owing to its anticancer effects. Despite the crucial role of dendritic cells (DCs) in immune homeostasis... -
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- Paeonol accelerates skin wound healing by regulating macrophage polarization and inflammation in diabetic rats
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Zhang Z, Chen T, Liu W, Xiong J, Jiang L, Liu M
- KMID: 2545534
- Korean J Physiol Pharmacol.
- 2023 Sep;27(5):437-448.
- doi: 10.4196/kjpp.2023.27.5.437
Diabetic ulcer is usually seen in people with uncontrolled blood sugar. Reportedly, many factors such as impaired glucose metabolism, and macrovascular and microvascular diseases caused angiogenesis disorders and delayed the healing... -
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