- Glycine induces enhancement of bactericidal activity of neutrophils
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Kang SH, Ham HY, Hong CW, Song DK
- KMID: 2530941
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):229-238.
- doi: kjpp.2022.26.4.229
Severe bacterial infections are frequently accompanied by depressed neutrophil functions. Thus, agents that increase the microbicidal activity of neutrophils could add to a direct antimicrobial therapy. Lysophosphatidylcholine augments neutrophil bactericidal... -
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- Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells
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Kang M, Heo R, Park S, Mun SY, Park M, Han ET, Han JH, Chun W, Ha KS, Park H, Jung WK, Choi IW, Park WS
- KMID: 2530947
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):277-285.
- doi: 10.4196/kjpp.2022.26.4.277
To investigate the adverse effects of clozapine on cardiovascular ion channels, we examined the inhibitory effect of clozapine on voltage-dependent K+(Kv) channels in rabbit coronary arterial smooth muscle cells. Clozapine-induced... -
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- Oxytocin-induced endothelial nitric oxide dependent vasorelaxation and ERK1/2-mediated vasoconstriction in the rat aorta
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Xu Q, Zhuo K, Zhang X, Zhang Y, Xue J, Zhou MS
- KMID: 2530945
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):255-262.
- doi: 10.4196/kjpp.2022.26.4.255
Oxytocin is a neuropeptide produced primarily in the hypothalamus and plays an important role in the regulation of mammalian birth and lactation. It has been shown that oxytocin has important... -
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- Adipose-derived stem cells decolonize skin Staphylococcus aureus by enhancing phagocytic activity of peripheral blood mononuclear cells in the atopic rats
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Lee J, Park L, Kim H, Rho Bi, Han RT, Kim S, Kim HJ, Na HS, Back SK
- KMID: 2530949
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):287-295.
- doi: 10.4196/kjpp.2022.26.4.287
Staphylococcus aureus (S. aureus ) is known to induce apoptosis of host immune cells and impair phagocytic clearance, thereby being pivotal in the pathogenesis of atopic dermatitis (AD). Adipose-derived stem... -
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- Comprehensive investigations of key mitochondrial metabolic changes in senescent human fibroblasts
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Ghneim HK, Alfhili MA, Alharbi SO, Alhusayni SM, Abudawood M, Aljaser FS, Al-Sheikh YA
- KMID: 2530946
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):263-275.
- doi: 10.4196/kjpp.2022.26.4.263
There is a paucity of detailed data related to the effect of senescence on the mitochondrial antioxidant capacity and redox state of senescent human cells. Activities of TCA cycle enzymes, respiratory... -
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- MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling
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Zhang S, Sun P, Xiao X, Hu Y, Qian Y, Zhang Q
- KMID: 2530943
- Korean J Physiol Pharmacol.
- 2022 Jul;26(4):239-253.
- doi: 10.4196/kjpp.2022.26.4.239
Epithelial-mesenchymal transition (EMT ) is known to be involved in airway remodeling and fibrosis of bronchial asthma. However, the molecular mechanisms leading to EMT have yet to be fully clarified.... -
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