- Role of Endoplasmic Reticulum Stress in Rheumatoid Arthritis Pathogenesis
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Park YJ, Yoo SA, Kim WU
- KMID: 1796908
- J Korean Med Sci.
- 2014 Jan;29(1):2-11.
- doi: 10.3346/jkms.2014.29.1.2
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by abnormal proliferation of synoviocytes, leukocyte infiltration, and angiogenesis. The endoplasmic reticulum (ER) is the site of biosynthesis for all secreted... -
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- Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide
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Cha HS, Bae EK, Ahn JK, Lee J, Ahn KS, Koh EM
- KMID: 1078358
- Exp Mol Med.
- 2010 Jun;42(6):428-436.
- doi: 10.3858/emm.2010.42.6.044
Inadequate apoptosis contributes to synovial hyperplasia in rheumatoid arthritis (RA). Recent study shows that low expression of Puma might be partially responsible for the decreased apoptosis of fibroblast-like synoviocytes (FLS).... -
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- Engagement of Toll-Like Receptor 3 Induces Vascular Endothelial Growth Factor and Interleukin-8 in Human Rheumatoid Synovial Fibroblasts
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Moon SJ, Park MK, Oh HJ, Lee SY, Kwok SK, Cho ML, Ju JH, Park KS, Kim HY, Park SH
- KMID: 964725
- Korean J Intern Med.
- 2010 Dec;25(4):429-435.
- doi: 10.3904/kjim.2010.25.4.429
BACKGROUND/AIMS: Angiogenesis, which is a critical step in the initiation and progression of rheumatoid arthritis (RA), involves pro-angiogenic factors, including interleukin (IL)-8 and vascular endothelial growth factor (VEGF). We investigated... -
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- Eupatilin Ameliorates Collagen Induced Arthritis
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Kim J, Kim Y, Yi H, Jung H, Rim YA, Park N, Jung SM, Park SH, Ju JH
- KMID: 2133298
- J Korean Med Sci.
- 2015 Mar;30(3):233-239.
- doi: 10.3346/jkms.2015.30.3.233
Eupatilin is the main active component of DA-9601, an extract from Artemisia. Recently, eupatilin was reported to have anti-inflammatory properties. We investigated the anti-arthritic effect of eupatilin in a murine... -
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