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Effect of Sulfhydryl Compounds on Melanosomal Morphology of Epidermal Melanocytes in UV - Irradiated Black Mice

Han KW, Myung KB, Hahm JH, Kook HI

  • KMID: 2231426
  • Korean J Dermatol.
  • 1987 Oct;25(5):553-561.
The present study was performed to evaluate the effect of sulfhydryl compounds, cysteine and glutathione, on the size of melanosomes and the ratio of melanosormai stages of epidermal melanocytes...
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Oxidation of the Sulfhydryl Group by Cephalosporins

Song DU, Chay KO, Jung YD, Kim YJ, Yang SY, Lee MW, Ahn BW

  • KMID: 2172506
  • Chonnam Med J.
  • 1999 Mar;35(1):61-68.
To investigate the mechanism for the adverse reactions of cephalosporins, their ability to oxidize reduced glutathione(GSH) and other sulfhydryl compounds was examined. All the six kinds of cephalosporins used could...
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Transthyretin Stimulates Autooxidation of Reduced Glutathione

Park JK, Jung S, Kim JH, Kim SH, Kang SS, Lee JH, Ahn BW

  • KMID: 1673072
  • J Korean Neurosurg Soc.
  • 1994 Aug;23(8):916-923.
When reduced glutathione(GSH) was incubated at neutral pH and at 37degrees, its concentration decteased slowly with formation of oxidized glutathione(GSSG). Autooxidation of GSH was accelerated by Cu2+ and Hg2+, but...
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A Study on the Protective Effects of Glutathione on Cytotoxicity of Mercury and Cadmium

Jeong JH, Kim JY, Koh DH

  • KMID: 2282994
  • Korean J Prev Med.
  • 1999 Jun;32(2):170-176.
OBJECTIVES: To evaluate the protective effects of glutathione (GSH) on the cytotoxicity of mercurial compounds(CH3HgCl, HgCl2) or cadmium chloride(CdCl2) in EMT-6 cells. METHODS: The compounds investigated were CH3HgCl, HgCl2, CdCl2, GSH,...
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Interaction between Inorganic Mercury and Selenium on Tissue Sulfhydryl Groups and Glutathione-linked Enzymes in Rats

Oh SH, Lee MH

The effect of selenium on the tissue sulfhydryl group content and lipid peroxide-destorying enzyme system in the liver, kidney and testis of rat treated with mercury was investigated. The male...
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Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. II. Kinetic properties of AP DNA endonucleases in rat liver chromatin

Kim YS, Kim JW, Lee SE, Oh SH

An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about...
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Recurrent Insulin Autoimmune Syndrome Caused by alpha-Lipoic Acid in Type 2 Diabetes

Bae SM, Bae MN, Kim EY, Kim IK, Seo MW, Shin JK, Cho SR, Jeong GH

Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies in the absence of exogenous insulin administration. Some drugs containing sulfhydryl compounds are known to initiate the...
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Sulfhydryl modification affects coronary artery tension by changing activity of delayed rectifier K+ current

Ha M, Kwon S, Lee YH, Yeon D, Ahn DS

It has been reported that a change in the cellular redox state may be involved in the regulation of vascular tone, but the underlying mechanism is not fully understood. The...
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Thiol Disulfide Homeostasis in Schizophrenic Patients Using Atypical Antipsychotic Drugs

Dogan HO, Ersan EE, Aydin H, Erdoğan S, Erşan S, Alişik M, Bakir S, Erel O, Koç D

OBJECTIVE: Schizophrenia is a severe, debilitating mental disorder characterized by behavioral abnormalities. Although several studies have investigated the role of oxidative stress and the effects of antipsychotic drugs on oxidative...
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Relationship of Oxidative Stress in Hepatitis B Infection Activity with HBV DNA and Fibrosis

Duygu F, Karsen H, Aksoy N, Taskin A

BACKGROUND: The aim of this study was to evaluate oxidative stress in various clinical forms of hepatitis B infection and to investigate its role in the development of the chronic...
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Oxidative Stress in the Heart of Rats Infected with Trypanosoma evansi

Baldissera MD, Souza CD, Bertoncheli CM, da Silveira KL, Grando TH, Porto BC, Leal DB, Silva AS, Mendes RE, Stefani LM, Monteiro S

This study was conducted to investigate the occurrence of oxidative stress in the heart tissue of rats infected with Trypanosoma evansi. Rats were divided into 2 groups (A and B)...
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Gold compound auranofin inhibits I kappaB kinase (IKK) by modifying Cys-179 of IKK beta subunit

Jeon KI, Byun MS, Jue DM

  • KMID: 1097252
  • Exp Mol Med.
  • 2003 Apr;35(2):61-66.
Antirheumatic gold compounds have been shown to inhibit NF-kB activation by blocking IkB kinase (IKK) activity. To examine the possible inhibitory mechanism of gold compounds, we expressed wild type and...
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Cardioprotective Potency of the Antioxidante Amifostine in the Ischemic and Reperfused Isolated Rat Heart

Huh GB, Chun SB

  • KMID: 1987819
  • Korean J Thorac Cardiovasc Surg.
  • 1998 Sep;31(9):845-854.
BACKGROUND: S-2-(3 aminoprophlamino) ethylphosphorothioic acid (WR-2721) is one of the radical scavenging thiols. We tested its protective effects in the reperfused heart. MATERIAL AND METHOD: The experimental setup was the...
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Study on Effective Preservation of Bovine Pericardium Using Decellularization and alpha-galactosidase for Eliminating Xenoreactive Antigen

Kim MS, Park CJ, Kim SH, Lim HG, Kim YJ

  • KMID: 2063055
  • Korean J Thorac Cardiovasc Surg.
  • 2010 Dec;43(6):576-587.
BACKGROUND: Effective decellularization and fixation process is critical, in order to use xenogenic valves clinically. In the present study, we decellularized bovine pericardium using sodium dodecyl sulfate (SDS) and N-lauroyl...
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Evaluation of thiol broth for the culture of Salmonella typhi and other bacteria from blood

Chong Y, Kang MS, Lee SY

Thiol broth is known to neutralize various antimicrobial agents. Positivity of growth of various species of bacteria from blood in thiol broth was reported as similar to that in tryptic...
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Histopathological changes of testes and eyes by neutron irradiation with boron compounds in mice

Kim YJ, Yoon WK, Ryu SY, Chun KJ, Son HY, Cho SW

This study was performed to investigate the biological effects of boron neutron capture therapy (BNCT) on the testes and eyes in mice using HANARO Nuclear Reactor, Korea Atomic Energy Research...
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Differential Effect of gamma-radiation-induced Heme Oxygenase-1 Activity in Female and Male C57BL/6 Mice

Han Y, Platonov A, Akhalaia M, Yun YS, Song JY

Ionizing radiation produces reactive oxygen species, which exert diverse biological effects on cells and animals. We investigated alterations of heme oxygenase (HO) and non-protein thiols (NPSH), which are known as...
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