- Helicobacter pylori and Telomerase Activity in Intestinal Metaplasia of the Stomach
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Chung IK, Hwang KY, Kim IH, Kim HS, Park SH, Lee MH, Kim CJ, Kim SJ
- KMID: 759615
- Korean J Intern Med.
- 2002 Dec;17(4):227-233.
BACKGROUND: Helicobacter pylori (H. pylori) has been considered a definitive carcinogen in gastric cancer. Telomerase is activated in gastric cancer and some premalignant gastric lesions, including intestinal metaplasia (IM).... -
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- Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells
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Kang DW, Min G, Park DY, Hong KW, Min DS
- KMID: 1104382
- Exp Mol Med.
- 2010 Aug;42(8):555-564.
- doi: 10.3858/emm.2010.42.8.056
Rebamipide a gastroprotective drug, is clinically used for the treatment of gastric ulcers and gastritis, but its actions on gastric cancer are not clearly understood. Phospholipase D (PLD) is overexpressed... -
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- Expression of Cyclooxygenase-2 and Bcl-2 in Human Gastric Adenomas
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Park JH, Kang KH, Kim SH, Lee JH, Cho CM, Kweon YO, Kim SK, Choi YH, Bae HI, Kim MS
- KMID: 1782230
- Korean J Intern Med.
- 2005 Sep;20(3):198-204.
- doi: 10.3904/kjim.2005.20.3.198
BACKGROUND: Cyclooxygenase (COX) -2 is the rate-limiting enzyme in prostaglandin synthesis. An increased expression has been implicated in the development and progression of human gastric cancers and colorectal adenomas and... -
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- Cyclooxygenase 2 in Gastric Carcinoma Is Expressed in Doublecortin- and CaM Kinase-Like-1-Positive Tuft Cells
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Mutoh H, Sashikawa , Sakamoto H, Tateno T
- KMID: 2070061
- Gut Liver.
- 2014 Sep;8(5):508-518.
- doi: 10.5009/gnl13237
BACKGROUND/AIMS: Doublecortin and CaM kinase-like-1 (DCAMKL1) is a marker of stem cells expressed predominantly in the crypt base in the intestine. However, DCAMKL1-positive cells have been shown to be differentiated... -
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- Overexpression of tissue inhibitors of metalloproteinase-1 and -2 in the stroma of gastric cancer
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Hong SI, Park IC, Hong WS, Son YS, Lee SH, Lee JI, Choi DW, Moon NM, Choe TB, Jang JJ
- KMID: 645010
- J Korean Med Sci.
- 1996 Dec;11(6):474-479.
- doi: 10.3346/jkms.1996.11.6.474
The fundamental event of cancer invasion and metastasis is the complicated interaction of cancer cells with host cells, in which event, a number of proteases and their inhibitors are involved.... -
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- Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines
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Lee KH, Choi EY, Kim MK, Hyun MS, Jang BI, Kim TN, Kim SW, Song SK, Kim JH, Kim JR
- KMID: 1105274
- Exp Mol Med.
- 2006 Feb;38(1):27-35.
The regulatory mechanisms for the proliferation and the particular invasive phenotypes of stomach cancers are not still fully understood. Up-regulations of hepatocytes growth factor (HGF), its receptor (c-Met), and urokinase-type... -
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- Relationship Between the Extent of Chromosomal Losses and the Pattern of CpG Methylation in Gastric Carcinomas
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Hong SJ, Kim YH, Choi YD, Min KO, Choi SW, Rhyu MG
- KMID: 1781762
- J Korean Med Sci.
- 2005 Oct;20(5):790-805.
- doi: 10.3346/jkms.2005.20.5.790
The extent of unilateral chromosomal losses and the presence of microsatellite instability (MSI) have been classified into high-risk (high- and baseline-level loss) and low-risk (low-level loss and MSI) stem-line genotypes... -
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- Decreased Expression of 15-hydroxyprostaglandin Dehydrogenase in Gastric Carcinomas
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Jang TJ, Ji YS, Jung KH
- KMID: 1782939
- Yonsei Med J.
- 2008 Dec;49(6):917-922.
- doi: 10.3349/ymj.2008.49.6.917
PURPOSE: Gastric carcinoma tissues release high level of prostaglandin E2 (PGE2) when compared to non-neoplastic mucosa, and cyclooxygenase-2 (COX-2), which is the rate-limiting enzyme in prostaglandin (PG) biosynthesis, is often... -
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