- High Plasma Sphingosine 1-phosphate Levels Predict Osteoporotic Fractures in Postmenopausal Women: The Center of Excellence for Osteoporosis Research Study
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Ardawi MS, Rouzi AA, Al-Senani , Qari MH, Elsamanoudy AZ, Mousa SA
- KMID: 2413370
- J Bone Metab.
- 2018 May;25(2):87-98.
- doi: 10.11005/jbm.2018.25.2.87
BACKGROUND: Higher sphingosine 1-phosphate (S1P) plasma levels are associated with decreased bone mineral density (BMD), and increased risk of prevalent vertebral fracture. So, we hypothesized that postmenopausal women with increased... -
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- Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery
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Park SJ, Im DS
- KMID: 2367621
- Biomol Ther.
- 2017 Jan;25(1):80-90.
- doi: 10.4062/biomolther.2016.160
Initial discovery on sphingosine 1-phosphate (S1P) as an intracellular second messenger was faced unexpectedly with roles of S1P as a first messenger, which subsequently resulted in cloning of its G... -
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- Association of Bone Marrow Sphingosine 1-phosphate Levels with Osteoporotic Hip Fractures
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Ahn SH, Koh JM, Gong EJ, Byun S, Lee SY, Kim BJ, Lee SH, Chang JS, Kim GS
- KMID: 2286295
- J Bone Metab.
- 2013 Nov;20(2):61-65.
- doi: 10.11005/jbm.2013.20.2.61
BACKGROUND: Sphingosine 1-phosphate (S1P) has been discovered to be a critical regulator of bone metabolism. Very recently, we found that higher circulating S1P levels were associated with higher rate of... -
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- Analysis of a Sphingosine 1-phosphate Receptor hS1P3 in Rat Hepatoma Cells
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Im DS
- KMID: 2285242
- Korean J Physiol Pharmacol.
- 2002 Jun;6(3):139-142.
To examine intracellular signaling of human S1P3 (hS1P3), a sphingosine 1-phosphate (S1P) receptor in plasma membrane, hS1P3 DNA was transfected into RH7777 rat hepatoma cell line, and the inhibition of... -
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