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Sympathetic and parasympathetic regulation of sodium transporters and water channels in rat submandibular gland

Jung H, Ryu SY

  • KMID: 2190348
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Feb;32(1):1-7.
The present study was aimed to explore the role of sympathetic and parasympathetic nerves in the regulation of sodium transporters and water channels in the salivary gland. Rats were denervated...
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Anesthesia and sodium channel

Kim HJ

  • KMID: 1482461
  • Hanyang Med Rev.
  • 2008 Nov;28(4):36-39.
Voltage-gated sodium channels are large glycoproteins that permit selective sodium ion conduction in excitable cells such as neurons. They generate upstroke of action potential and transmit depolarizing impulses through the...
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Autonomic Neural Regulation of Sodium Transporters and Water Channels in Rat Submandibular Gland

Ryu SY, Jung H, Kim KY, Kim M, Lee JU

  • KMID: 2071622
  • Korean J Physiol Pharmacol.
  • 2006 Apr;10(2):65-69.
The present study was undertaken to explore the role of autonomic nerves in the regulation of sodium transporters and water channels in the salivary gland. Rats were denervated of their...
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Hypertensive Hypokalemic Disorders

Choi KB

Hypokalemia is a common clinical problem. The kidney is responsible for long term potassium homoeostasis, as well as the serum potassium concentration. The main nephron site where K secretion is...
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Pathophysiological Implications of Sodium Transporters and Water Channels in the Kidney

Kim SW, Ma SK, Bae EH, Park JW, Lee JU

  • KMID: 2253199
  • Korean J Nephrol.
  • 2009 Jan;28(1):1-9.
Renal sodium and water reabsorption occurs through epithelial sodium transporters and aquaporin (AQP) water channels in various segments of tubules. We have demonstrated altered regulation of these transporters and channels...
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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

Shin HJ, Lim H

  • KMID: 2328241
  • J Korean Soc Clin Toxicol.
  • 2016 Jun;14(1):60-65.
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine....
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An atypical phenotype of hypokalemic periodic paralysis caused by a mutation in the sodium channel gene SCN4A

Park YH, Kim JB

Familial hypokalemic periodic paralysis is an autosomal-dominant channelopathy characterized by episodic muscle weakness with hypokalemia. The respiratory and cardiac muscles typically remain unaffected, but we report an atypical case of...
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Control of Na+ channels in salivary duct cells

Dinudom A, Komwatana , Young J, Cook D

No abstract available.
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Water and Sodium Regulation in Heart Failure

Bae EH, Ma SK

Heart failure is the pathophysiological state characterized by ventricular dysfunction and associated clinical symptoms. Decreased cardiac output or peripheral vascular resistance lead to arterial underfilling. That is an important signal...
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A Case of Electrocardiographic and Mental Change in a Patient with a Diphenhydramine Overdose

Park CS, Kang IG, Ryu HS, Park SS, Lee MJ, Jeong WJ

  • KMID: 2332762
  • J Korean Soc Emerg Med.
  • 2010 Jun;21(3):405-411.
The antihistaminic drug diphenhydramine is mainly used as a sedative, hypnotic and antiemetic. In many countries it is available over-the-counter, very common, and generally regarded as a harmless drug. However,...
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Effects of Fluoxetine on Sodium Currents in Rat Sensory Neurons

Ha HW, Han JH, Jang YY, Shin YK, Lee CS, Song JH

  • KMID: 2342862
  • J Korean Neurol Assoc.
  • 2000 Nov;18(6):754-763.
BACKGROUND: Fluoxetine, a widely used antidepressant drug, has been described as a selective serotonin reuptake inhibitor. In addition to its antidepressant action it has been demonstrated to be effective in...
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Polymorphisms in the Voltage-gated Sodium Channel Genes and Antiepileptic Efficacy of Carbamazepine

Jang SY, Kim MK, Nam TS, Kim JT, Choi SM, Lee SH, Park MS, Kim BC, Cho KH

  • KMID: 2185031
  • J Korean Neurol Assoc.
  • 2009 May;27(2):147-153.
BACKGROUND: Voltage-gated sodium channels are responsible for the initial-depolarization component of action potentials in brain neurons, and hence they are the target for widely used antiepileptic drugs such as carbamazepine...
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The effects of pain-producing agents on the voltage-dependent ionic channels of rat trigeminal ganglion

Kim EC, Lee SC

  • KMID: 1580293
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2004 Jan;26(1):116-129.
Ion channels of the sensory neurons play a pivotal role in the generation and transmission of sensory information. Generally the Na+ channels are involved in the rapid generation of action...
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Cystic fibrosis lung disease: Current perspectives

Jung JA

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or...
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Inhibitory Effects of Valdecoxib on Sodium Currents in Sensory Neurons

Cho JS, Kim TH, Shin YK, Lee CS, Park M, Song JH

  • KMID: 2185260
  • J Korean Neurol Assoc.
  • 2007 Feb;25(1):81-91.
BACKGROUND: Valdecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. It is effective in the treatment of rheumatoid arthritis, osteoarthritis, primary dysmenorrhea, and postoperative pain. Two kinds of sodium currents, tetrodotoxin-sensitive (TTX-S)...
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Dysregulation of ENaC in Animal Models of Nephrotic Syndrome and Liver Cirrhosis

Kim SW

Nephrotic syndrome and liver cirrhosis are common clinical manifestations, and are associated with avid sodium retention leading to the development of edema and ascites. However, the mechanism for the sodium...
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A Family with A Missense Mutation in the SCN5A Gene

Shin CH, Kim NH, Kim KH, Yoo SS, Choi YB, Oh SK, Hong KM, Jeong JW, Paik MK

Brugada syndrome, an autosomal dominantly inherited form of ventricular fibrillation, is characterized by ST-segment elevation in leads V1-3 and right bundle-branch block on surface electrocardiogram. It is caused by mutations...
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A Case of Idiopathic Brugada ECG Pattern Developed in Relation To Fever

Kim YH, Cho BR, Lee SW, Lee HY, Her AY, Choi DW, Cho JH

  • KMID: 1577528
  • J Korean Geriatr Soc.
  • 2005 Mar;9(1):66-69.
Brugada syndrome is characterized by a peculiar ST-segment elevation in the right precordial leads often associated with a right bundle branch block(RBBB) pattern. Mutations in a cardiac sodium channel gene...
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Familial hyperkalemic periodic paralysis caused by a de novo mutation in the sodium channel gene SCN4A

Han JY, Kim JB

Familial hyperkalemic periodic paralysis (HYPP) is an autosomaldominant channelopathy characterized by transient and recurrent episodes of paralysis with concomitant hyperkalemia. Mutations in the skeletal muscle voltage-gated sodium channel gene SCN4A...
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Transient Diabetes Insipidus Associated with Tetrodotoxin Intoxication: A Case Report

Wi DH

  • KMID: 2333321
  • J Korean Soc Emerg Med.
  • 2013 Apr;24(2):230-235.
Ingestion of puffer fish can result in severe and potentially lethal intoxication, referred to as tetrodotoxin intoxication. Tetrodotoxin is a potent neurotoxin well known for its ability to ability neuromuscular...
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