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Sonic Hedgehog Pathway as the Prognostic Marker in Patients with Extensive Stage Small Cell Lung Cancer

Lim S, Lim SM, Kim MJ, Park SY, Kim JH

PURPOSE: Sonic hedgehog (Shh) signaling pathway is known to play a crucial role in carcinogenesis in various malignancies, including lung cancer regarding tumorigenesis, angiogenesis, and cellular differentiation. The aim of...
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Higher thoracic radiation dose is beneficial in patients with extensive small cell lung cancer

Yoon HG, Noh JM, Ahn YC, Oh D, Pyo H, Kim H

PURPOSE: The effectiveness of thoracic radiation therapy (TRT) in extensive-stage small cell lung cancer (ES-SCLC) patients is increasingly reported, but there is no definite consensus on its application. The aim...
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The value of prophylactic cranial irradiation in limited-stage small cell lung cancer: should it always be recommended?

Koh M, Song SY, Jo JH, Park G, Park JW, Kim SS, Choi EK

PURPOSE: Prophylactic cranial irradiation (PCI) is a standard treatment for limited-stage small cell lung cancer (LS-SCLC) showing a response to initial treatment, but many patients do not receive PCI due...
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Bone marrow metastasis of small cell lung carcinoma with spontaneous tumor lysis syndrome without hepatic metastasis at diagnosis: first case report in Korea and review of literature

Park SH, Lim JH, Jeong J, Lee SH, Cha HJ, Choi Y, Jo JC

No abstract available.
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Paraneoplastic Chorea Associated with Anti-Hu Antibody and Small Cell Lung Carcinoma

Ko J, Kim T, Kwon HJ, Hong JY

No abstract available.
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Randomized Phase III Trial of Irinotecan Plus Cisplatin versus Etoposide Plus Cisplatin in Chemotherapy-Naïve Korean Patients with Extensive-Disease Small Cell Lung Cancer

Kim DW, Kim HG, Kim JH, Park K, Kim HK, Jang JS, Kim BS, Kang JH, Lee KH, Kim SW, Ryoo HM, Kim JS, Lee KH, Kwon JH, Choi JH, Shin SW, Hahn S, Heo DS

PURPOSE: This randomized phase III study was designed to compare the efficacy and safety of irinotecan plus cisplatin (IP) over etoposide plus cisplatin (EP) in Korean patients with extensive-disease small-cell...
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Prognostic Value of Pre- and Post-Treatment FDG PET/CT Parameters in Small Cell Lung Cancer Patients

Kim H, Yoo IR, Boo SH, Park HL, O JH, Kim SH

PURPOSE: To evaluate the prognostic value of PET parameters obtained from pre- and post-treatment FDG PET/CT examinations in patients with SCLC. METHODS: Fifty-nine patients with initially diagnosed SCLC from 2009 to...
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Partial spontaneous remission of small cell lung carcinoma with neurologic symptom

Yun KH, Song SH, Kim CH, Hwang CH, Lee JH, Choi JH, Kim SY

Small cell lung carcinoma (SCLC) is a cancer that shows aggressive behavior, early spread to distant sites, and frequent association with distinct paraneoplastic syndromes. Spontaneous remission of cancer, particularly of...
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The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer

Cho SH, Kim JI, Kim HS, Park SD, Jang KW

BACKGROUND: The mesenchymal-epithelial transition factor (MET) receptor can be overexpressed in solid tumors, including small cell lung cancer (SCLC). However, the molecular mechanism regulating MET stability and turnover in SCLC...
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A Case of Small Cell Lung Cancer Diagnosed via Incisional Biopsy of an Orbital Mass

Jeon H, Cho MH, Choi HY

PURPOSE: To report a case of an orbital mass diagnosed as metastasis from small cell lung cancer and to provide a review of the literature. CASE SUMMARY: A 66-year-old male with...
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The Younger Patients Have More Better Prognosis in Limited Disease Small Cell Lung Cancer

Kim HJ, Choi CM, Kim SG

BACKGROUND: Factors associated with the prognosis of patients with small cell lung cancer (SCLC) is relatively unknown, than of those with non-small cell lung cancer. This study was undertaken to...
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Transformation to Small Cell Lung Cancer of Pulmonary Adenocarcinoma: Clinicopathologic Analysis of Six Cases

Ahn S, Hwang SH, Han J, Choi YL, Lee SH, Ahn JS, Park K, Ahn MJ, Park WY

BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are considered the first line treatment for a subset of EGFR-mutated non-small cell lung cancer (NSCLC) patients. Although transformation to...
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Cutaneous Metastasis of Small Cell Lung Cancer Masquerading as Lipomatosis

Min J, Choi J, Seo HM, Lee HJ, Nam JH, Jung HJ, Park JH, Lee GY, Kim WS

  • KMID: 2251153
  • Korean J Dermatol.
  • 2016 May;54(4):304-306.
No abstract available.
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A Phase II Study of Weekly Paclitaxel Plus Gemcitabine as a Second-Line Therapy in Patients with Metastatic or Recurrent Small Cell Lung Cancer

Yun T, Kim HT, Han JY, Yoon SJ, Kim HY, Nam BH, Lee JS

PURPOSE: Paclitaxel (P) and gemcitabine (G) are clinically synergistic in small cell lung cancer (SCLC). We evaluated the efficacy of PG as a salvage treatment for SCLC patients whose disease...
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Correlation between Semi-Quantitative 18F-FDG PET/CT Parameters and Ki-67 Expression in Small Cell Lung Cancer

Park S, Lee E, Rhee S, Cho J, Choi S, Lee S, Eo JS, Pahk K, Choe JG, Kim S

PURPOSE: The aimof this study was to evaluate the relationship between semiquantitative parameters on 18F-FDG PET/CT including maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), metabolic tumor volume...
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Delayed Diagnosis of Small Cell Lung Cancer in a Patient with Allergic Bronchopulmonary Aspergillosis

Jung WS, Jang JW, Park SY, Choe YH, Lee YC, Kim SR

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity disorder induced by Aspergillus fumigatus that occurs generally in patients with underlying chronic airway disorders. However, the development of ABPA associated with lung...
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A Case of Ectopic Adrenocorticotropic Hormone Syndrome in Small Cell Lung Cancer

Jeong C, Lee J, Ryu S, Lee HY, Shin AY, Kim JS, Ahn JH, Kang HS

Small cell lung cancer (SCLC), which originated from neuroendocrine tissue, can develop into paraneoplastic endocrine syndromes, such as Cushing syndrome, because of an inappropriate secretion of ectopic adrenocorticotropic hormone (ACTH)....
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Small Cell Lung Cancer with Mutation of Epidermal Growth Factor Receptor in Patients with Lung Adenocarcinoma Resistant to Gefitinib

Yun JT, Park SY, Yang YJ, Park JC, Jung JW, Kim JO, Lee JU

Most epidermal growth factor receptor (EGFR) gene mutations are detected in lung adenocarcinomas. In contrast, these mutations have rarely been reported in small cell lung cancer (SCLC). We herein report...
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Early treatment volume reduction rate as a prognostic factor in patients treated with chemoradiotherapy for limited stage small cell lung cancer

Lee J, Lee J, Choi J, Kim JW, Cho J, Lee CG

PURPOSE: To investigate the relationship between early treatment response to definitive chemoradiotherapy (CRT) and survival outcome in patients with limited stage small cell lung cancer (LS-SCLC). MATERIALS AND METHODS: We retrospectively...
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A Rare Case of Primary Thymic Adenocarcinoma Mimicking Small Cell Lung Cancer

Cho EN, Park HS, Kim TH, Byun MK, Kim HJ, Ahn CM, Chang YS

Primary thymic adenocarcinoma is a very rare malignancy of the anterior mediastinum with no standardized treatment. A 36-year-old male patient presented with hoarseness over the past 3 months. A chest...
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