- Qualification and application of liquid chromatography-quadrupole time-offlight mass spectrometric method for the determination of carisbamate in rat plasma and prediction of its human pharmacokinetics using physiologically based pharmacokinetic modeling
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Lee Bi, Lim Jh, Park MH, Shin SH, Byeon JJ, Choi Jm, Park Sj, Park Mj, Park Y, Shin YG
- KMID: 2512002
- Transl Clin Pharmacol.
- 2020 Sep;28(3):147-159.
- doi: 10.12793/tcp.2020.28.e15
Carisbamate is an antiepileptic drug and it also has broad neuroprotective activity and anticonvulsant reaction. In this study, a liquid chromatography-quadrupole time-of-flight mass spectrometric (LC-qTOF-MS) method was developed and applied... -
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- Spine Surgery Using Augmented Reality
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Park SM, Kim HJ, Yeom JS, Shin YG
- KMID: 2442345
- J Korean Soc Spine Surg.
- 2019 Mar;26(1):26-32.
- doi: 10.4184/jkss.2019.26.1.26
STUDY DESIGN: Review article. OBJECTIVES: To present the latest knowledge on spine surgery using augmented reality (AR). SUMMARY OF LITERATURE REVIEW: AR is a new technology that simulates interactions with real-world surroundings... -
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- A Case of Middle Ear Implantation Using the Vibrant Soundbridge in a Patient with Bilateral Mixed Hearing Loss
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Shin YG, Gu JW, Kang JW, Song MH
- KMID: 2430852
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2018 Dec;61(12):705-709.
- doi: 10.3342/kjorl-hns.2018.00374
It is challenging to achieve sufficient hearing gain in patients with mixed hearing loss. In chronic middle ear diseases, conventional passive reconstructive surgeries often result in suboptimal hearing gain and... -
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- Influence of Fatigability on the Timing of Reassessment in the Treatment of Posterior Canal Benign Paroxysmal Positional Vertigo
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Kim CH, Shin JE, Shin YG, Song MH, Shim DB
- KMID: 2430843
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2018 Dec;61(12):658-662.
- doi: 10.3342/kjorl-hns.2017.00353
BACKGROUND AND OBJECTIVES: The early assessment of treatment is not done for benign paroxysmal positional vertigo (BPPV) since the well-known phenomenon of fatigability after a repeated positional test can mimic... -
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- Spinal Enumeration by Morphologic Analysis of Spinal Variants: Comparison to Counting in a Cranial-To-Caudal Manner
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Yun S, Park S, Park JG, Huh JD, Shin YG, Yun JH
- KMID: 2424853
- Korean J Radiol.
- 2018 Dec;19(6):1140-1146.
- doi: 10.3348/kjr.2018.19.6.1140
OBJECTIVE: To compare the spinal enumeration methods that establish the first lumbar vertebra in patients with spinal variants. MATERIALS AND METHODS: Of the 1446 consecutive patients who had undergone computed tomography... -
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- A Patient with Sudden Hearing Loss with Vertigo Showing Exclusive Posterior Semicircular Canal Abnormality
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Gu JW, Shin YG, Song MH, Shim DB
- KMID: 2400996
- Res Vestib Sci.
- 2017 Dec;16(4):161-166.
- doi: 10.21790/rvs.2017.16.4.161
It is known that about 30% of patients with sudden hearing loss present with vertigo or dizziness. In clinical practice, this is called sudden hearing loss with vertigo (SHLV) although... -
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- Pseudo-Spontaneous Nystagmus and Head-Shaking Nystagmus in Horizontal Canal Benign Paroxysmal Positional Vertigo
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Shin YG, Gu JW, Kang JW, Song MH, Shim DB
- KMID: 2400990
- Res Vestib Sci.
- 2017 Dec;16(4):129-134.
- doi: 10.21790/rvs.2017.16.4.129
OBJECTIVES: The purpose of this study was to examine the clinical manifestations and significance of pseudo-spontaneous nystagmus (PSN) and head-shaking nystagmus (HSN) in horizontal canal benign paroxysmal positional vertigo (HC-BPPV). METHODS:... -
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- Compensation of the Postural Instability in Patients with Acute Unilateral Vestibular Neuritis: The Usefulness of Computerized Dynamic Posturography as an Objective Indicator
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Park JW, Shin YG, Gu JW, Song MH, Shim DB
- KMID: 2386111
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2017 Jun;60(6):295-300.
- doi: 10.3342/kjorl-hns.2017.00374
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the usefulness of computerized dynamic posturography (CDP) in patients with acute vestibular neuritis (AVN) by identifying the recovery period... -
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- Magnetic resonance imaging and pathological characteristics of pure mucinous carcinoma in the breast according to echogenicity on ultrasonography
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Shin YG, Kim EK, Kim MJ, Yoon JH, Moon HJ
- KMID: 2376064
- Ultrasonography.
- 2017 Apr;36(2):131-138.
- doi: 10.14366/usg.16028
PURPOSE: The aim of this study was to explore the clinical and pathological characteristics of pure mucinous breast carcinoma (PMBC) according to internal echogenicity on ultrasonography (US). METHODS: Thirty-three patients with... -
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- Detection of Breast Abnormalities on Enhanced Chest CT: Correlation with Breast Composition on Mammography
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Cho EM, Kang H, Shin YG, Yun JH, Oh KS, Park S
- KMID: 2367856
- J Korean Soc Radiol.
- 2017 Feb;76(2):96-103.
- doi: 10.3348/jksr.2017.76.2.96
PURPOSE: To investigate the capability of enhanced chest computed tomography (CT) for detecting breast abnormalities and to assess the influence of breast composition on this detectability. MATERIALS AND METHODS: From 2000... -
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- Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin
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Park MH, Shin SH, Byeon JJ, Lee GH, Yu BY, Shin YG
- KMID: 2371074
- Korean J Physiol Pharmacol.
- 2017 Jan;21(1):107-115.
- doi: 10.4196/kjpp.2017.21.1.107
Over the last decade, physiologically based pharmacokinetics (PBPK) application has been extended significantly not only to predicting preclinical/human PK but also to evaluating the drug-drug interaction (DDI) liability at the... -
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- Various Nystagmus Patterns and Their Clinical Significance in Benign Paroxysmal Positional Vertigo of Anterior Semicircular Canal
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Park JW, Shin YG, Gu JW, Song MH, Shim DB
- KMID: 2362287
- Res Vestib Sci.
- 2016 Dec;15(4):126-131.
- doi: 10.21790/rvs.2016.15.4.126
OBJECTIVE: The purpose of this study was to identify the diverse patterns of nystagmus and analyze their clinical significance in benign paroxysmal positional vertigo (BPPV) of the anterior semicircular canal. METHODS:... -
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- The Influence of Sleep Position on Benign Paroxysmal Positional Vertigo
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Shin YG, Park JW, Gu JW, Song MH, Shim DB
- KMID: 2362286
- Res Vestib Sci.
- 2016 Dec;15(4):121-125.
- doi: 10.21790/rvs.2016.15.4.121
OBJECTIVE: The purpose of this study was to identify the influence of sleep position on benign paroxysmal positional vertigo (BPPV). METHODS: Four hundred sixty patients diagnosed as posterior or horizontal canal... -
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- Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425
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Shin YG, Meijering , van Heuveln FH, Wieling J, Halladay J, Sahasranaman S, Hop CE
- KMID: 2351810
- Transl Clin Pharmacol.
- 2015 Dec;23(2):59-65.
- doi: 10.12793/tcp.2015.23.2.59
The development and validation of a method for the determination of concentrations of thiocyanate in human plasma are described here. A modified colorimetric method of Bowler was used with the... -
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- Clinical Characteristics of Horizontal Canal Benign Paroxysmal Positional Vertigo with Persistent Geotropic Direction Changing Positional Nystagmus
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Ko KM, Song MH, Park JW, Lee JH, Shin YG, Shim DB
- KMID: 2131317
- Res Vestib Sci.
- 2015 Dec;14(4):117-122.
- doi: 10.0000/rvs.2015.14.4.117
OBJECTIVE: The purpose of this study was to identify the clinical characteristics of horizontal canal benign paroxysmal positional vertigo (h-BPPV) with persistent geotropic direction changing positional nystagmus (DCPN). METHODS: One hundred... -
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- Comprehensive Factors Influencing Quality of Life of Elders Utilizing Senior Welfare Centers
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Kim EK, Shin YG, Jo EJ, Moon DS, Park KM, Kim EK, Lee SJ, Kim HJ, Ko HS
- KMID: 2315711
- Perspect Nurs Sci.
- 2015 Apr;12(1):50-59.
- doi: 10.16952/pns.2015.12.1.50
PURPOSE: The purpose of this study was to investigate the influencing factors on the quality of life of elders. METHODS: Data were collected from August 25, September 1, 2014, and participants... -
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- Development and Verification of Nested PCR Assay for Detection of Tobacco rattle virus in Plant Quarantine
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Lee S, Lee JY, Shin YG, Lee SH, Ahn TY
- KMID: 2168705
- J Bacteriol Virol.
- 2015 Mar;45(1):54-61.
- doi: 10.4167/jbv.2015.45.1.54
Tobacco rattle virus (TRV) is a plant pathogen belonging to the Group IV positive-sense single-stranded RNA viruses. TRV causes disease in various plants (e.g., potato, tomato and tobacco), for which... -
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- Ultrasonographic Features of Metastatic Lymph Nodes in Papillary Thyroid Microcarcinomas and Macrocarcinomas
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Shin YG, Kang H, Joh YD, Jeong KS, Kim BS
- KMID: 2002804
- J Korean Soc Radiol.
- 2015 Feb;72(2):92-100.
- doi: 10.3348/jksr.2015.72.2.92
PURPOSE: To analyze ultrasonographic (US) features of metastatic lymph nodes (LNs) in papillary thyroid microcarcinomas (PTMC) and in papillary thyroid macrocarcinomas. MATERIALS AND METHODS: The study reviewed US findings of 273... -
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- Factors Influencing Glycemic Control Response of Sitagliptin
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Kim GW, Kim JH, Lee MY, Shin JY, Shin YG, Ha EH, Chung CH
- KMID: 2173938
- J Korean Diabetes.
- 2013 Dec;14(4):206-211.
- doi: 10.4093/jkd.2013.14.4.206
BACKGROUND: Dipeptidyl peptidase 4 (DPP-4) inhibitors are proposed to reduce blood glucose in type 2 diabetes by prolonging the activity of circulating incretins. However, the factors that affect the efficacy... -
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- Peroxisome proliferator-activated receptor delta agonist attenuates hepatic steatosis by anti-inflammatory mechanism
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Lee MY, Choi R, Kim HM, Cho EJ, Kim BH, Choi YS, Naowaboot , Lee EY, Yang YC, Shin JY, Shin YG, Chung CH
- KMID: 1506221
- Exp Mol Med.
- 2012 Oct;44(10):578-585.
Although peroxisome proliferator receptor (PPAR)-alpha and PPAR-gamma agonist have been developed as chemical tools to uncover biological roles for the PPARs such as lipid and carbohydrate metabolism, PPAR-delta has not... -
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