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Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population

S, Modi A, Khokhar M, Sharma P, Joshi R, Mishra SS, Bharshankar RN, Tiwari S, Singh PK, Bhosale VV, Singh Negi MP

Background: It is well established that obesity is a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role in regulation of adipokines....
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Comparative evaluation of nasal and alveolar changes in complete unilateral cleft lip and palate patients using intraoral and extraoral nasoalveolar molding techniques: randomized controlled trial

Kalaskar R, Bhaje P, Sharma P, Balasubramanian S, Ninawe N, Ijalkar R

Objectives: Cleft lip and palate is a common congenital anomaly that impairs the aesthetics, speech, hearing, and psychological and social life of an individual. To achieve good aesthetic outcomes, presurgical...
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Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia

Sharma P, Kaushik P, Jain S, Sharma BM, Awasthi R, Kulkarni GT, Sharma B

Objective: Vascular Dementia (VaD), is associated with metabolic conditions. Diabetes is a major risk factor for the development of VaD. This study investigates the efficacy of ulinastatin (UTI) and sulforaphane...
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A comparative study between light transmission aggregometry and flow cytometric platelet aggregation test for the identification of platelet function defects in patients with bleeding

Sharma P, Sachdeva MUS, Kumar N, Bose S, Bose P, Uppal V, Malhotra P, Bansal D, Varma N, Ahluwalia J

Background Platelet aggregation studies using conventional light transmission aggregometry (LTA) have several disadvantages and require strict pre-analytical measures for reliable results. We aimed to examine the utility of flow cytometric platelet aggregation...
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Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India

Sharma P, Chawla R, Bakshi R, Saxena S, Basu S, Bharti PK, Dhuria M, Singh SK, Lal P

Objectives: Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The...
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Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19

Choudhary S, Sreenivasulu K, Mitra P, Misra S, Sharma P

Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries...
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Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis

Nanda A, K. T, Banerjee P, Dutta M, Wangdi T, Sharma P, Chaudhury K, Jana SK

Background: The effect of the interplay among inflammation, angiogenesis, extracellular matrix (ECM) degradation, and oxidative stress (OS) on the pathogenesis of endometriosis remains unclear. Previously, we demonstrated the role of...
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Effect of Mandibular Advancement Splint on Obstructive Sleep Apnea with Insulin Resistant Diabetes

Gupta A, Tripathi A, Rai P, Sharma P, Yadav V, Kumar D

Objectives: Obstructive Sleep apnea (OSA) is characterized by complete or partial obstruction of upper airflow despite the effort to breathe, leading to hypoxemia and hypercapnia. The resultant apnea causes sleep...
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Outcomes of Fast-Track Multidisciplinary Care of Hip Fractures in Veterans: A Geriatric Hip Fracture Program Report

Kulshrestha V, Sood M, Kumar S, Sharma P, Yadav YK

BACKGROUND: Hip fractures are a significant cause of morbidity and mortality in the elderly. Fast-track multidisciplinary co-management of these patients, rapid preoperative optimization, early surgery, and expeditious rehabilitation may minimize...
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microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways

Agarwal RG, Sharma P, Nyati KK

Our current knowledge of mycobacterial infections in humans has progressively increased over the past few decades. The infection of Mycobacterium tuberculosis causes tuberculosis (TB) disease, which has reasoned for excessive...
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Multifocal large aggregates of pseudo-Gaucher cells in chronic myeloid leukemia

Sharma P, Kumar N, Varma N

No abstract available.
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Role of liver transplantation in severe alcoholic hepatitis

Daswani R, Kumar A, Sharma P, Singla V, Bansal N, Arora A

Severe alcoholic hepatitis has very high short term mortality and corticosteroids have been the mainstay of treatment for decades. Patients with Lille score >0.45 are considered non-responders to steroids and...
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Auer rods in unusual sites: macrophage indigestion

Sharma P, Ahluwalia

No abstract available.
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Hypercalcemia, multiple osteolytic lesions, and acute renal failure: a rare presentation of B-cell acute lymphoblastic leukemia

Puri V, Sharma P, Gopalakrishnan S, Sikka M, Avasthi R

No abstract available.
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A case of histoplasmosis in a patient with MDS/MPN-U

Rastogi P, Sharma P, Kumar N, Rudramurthy SM, Varma N, Varma S

No abstract available.
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Plasma cell leukemia in North India: retrospective analysis of a distinct clinicohematological entity from a tertiary care center and review of literature

Bommannan , Sachdeva M, Malhotra P, Kumar N, Sharma P, Naseem S, Ahluwalia , Das R, Varma N, Prakash G, Khadwal A, Srinivasan R, Varma S

BACKGROUND: Plasma cell leukemia (PCL) is a rare and aggressive plasma cell neoplasm. In PCL, clonal plasma cells comprise ≥20% of the peripheral blood (PB) leukocytes and/or the absolute clonal...
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Metastatic Neuroendocrine Tumour in a Renal Transplant Recipient: Dual-Tracer PET-CT with 18F-FDG and 68Ga-DOTANOC in This Rare Setting

Karunanithi S, Roy SG, Sharma P, Yadav R, Bal C, Kumar R

Recipients of renal transplant are at increased risk of developing various malignancies, especially post-transplant lymphoproliferative disorder (PTLD) and skin cancers. Neuroendocrine tumours (NET) of the gastrointestinal tract have not been...
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Endodontic treatment of a mandibular first molar with 8 canals: a case report

Arora A, Acharya SR, Sharma P

Presented here is a case where 8 canals were located in a mandibular first molar. A patient with continuing pain in mandibular left first molar even after completion of biomechanical...
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Late Port Site Metastasis from Occult Gall Bladder Carcinoma After Laparoscopic Cholecystectomy for Cholelithiasis: The Role of 18F-FDG PET/CT

Sharma P, Chatterjee P

Late port site metastasis of gall bladder carcinoma (GBC) after laparoscopic cholecystectomy is a rare finding. Rarer still is such a presentation where the GBC remained occult at histopathology. 18F-flurodeoxyglucose...
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Arteriovenous Fistula of the Filum Terminale Misdiagnosed and Previously Operated as Lower Lumbar Degenerative Disease

Sharma P, Ranjan A, Lath R

Filum terminale arteriovenous fistula (FTAVF) presenting as a cause of failed back surgery syndrome is a rare entity. We report a 48-year-old male patient who presented with clinical features of...
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