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Attention and Working Memory Task-Load Dependent Activation Increase with Deactivation Decrease after Caffeine Ingestion

Peng W, Zhang J, Chang D, Shen ZW, Shang Y, Song D, Ge Q, Weng X, Wang Z

PURPOSE: Caffeine is the most widely consumed psychostimulant. It is often adopted as a tool to modulate brain activations in fMRI studies. However, its pharmaceutical effect on task-induced deactivation has...
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Molecular Characteristics and Potent Immunomodulatory Activity of Fasciola hepatica Cystatin

Zhang K, Liu Y, Zhang G, Wang X, Li Z, Shang Y, Ning C, Ji C, Cai X, Xia X, Qiao J, Meng Q

Cystatin, a cysteine protease inhibitor found in many parasites, plays important roles in immune evasion. This study analyzed the molecular characteristics of a cystatin from Fasciola hepatica (FhCystatin) and expressed...
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Establishment and application of a solid-phase blocking ELISA method for detection of antibodies against classical swine fever virus

Cao Y, Yuan L, Yang S, Shang Y, Yang B, Jing Z, Guo H, Yin S

Background: Classical swine fever (CSF) is a severe infectious disease of pigs that causes significant economic losses to the swine industry. Objectives: This study developed a solid-phase blocking enzyme-linked immunosorbent assay...
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Biological Characteristics of Recombinant Arthrobotrys oligospora Chitinase AO-801

Gong S, Meng Q, Qiao J, Huang Y, Zhong W, Zhang G, Zhang K, Li N, Shang Y, Li Z, Cai X

Chitinase AO-801 is a hydrolase secreted by Arthrobotrys oligospora during nematode feeding, while its role remained elusive. This study analyzed the molecular characteristics of recombinant chitinase of Arthrobotrys oligospora (reAO-801)....
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A Multi-stage Carcinogenesis Model to Investigate Caloric Restriction as a Potential Tool for Post-irradiation Mitigation of Cancer Risk

Tani S, Blyth BJ, Shang Y, Morioka T, Kakinuma S, Shimada Y

The risk of radiation-induced cancer adds to anxiety in low-dose exposed populations. Safe and effective lifestyle changes which can help mitigate excess cancer risk might provide exposed individuals the opportunity...
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Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake

Yang HX, Shang Y, Jin Q, Wu YL, Liu J, Qiao CY, Zhan ZY, Ye H, Nan JX, Lian LH

In current study, we aimed to investigate whether the gentiopicroside (GPS) derived from Gentiana manshurica Kitagawa could block the progression of alcoholic hepatic steatosis to fibrosis induced by chronic ethanol...
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The Clinical Feature of Behcet's Disease in Northeastern China

Shang Y, Han S, Li J, Ren Q, Song F, Chen H

PURPOSE: Behcet's disease (BD) is a chronic, relapsing, multi-system vasculitis of unknown aetiology with complicated and diversified clinical features predominantly involving oral and genital ulcers, and ocular and cutaneous lesions....
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In Vitro Activity of the Novel Tetracyclines, Tigecycline, Eravacycline, and Omadacycline, Against Moraxella catarrhalis

Sun X, Zhang B, Xu G, Chen J, Shang Y, Lin Z, Yu Z, Zheng J, Bai B

Background: Tigecycline, eravacycline, and omadacycline are recently developed tetracyclines. Susceptibility of microbes to these tetracyclines and their molecular mechanisms have not been well elucidated. We investigated the susceptibility of ...
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Selection and identification of singledomain antibody against Peste des Petits Ruminants virus

Liu D, Li L, Cao X, Wu J, Du G, Shang Y

Background: Peste des petits ruminants (PPR) is an infectious disease caused by the peste des petits ruminants virus (PPRV) that mainly produces respiratory symptoms in affected animals, resulting in great...
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