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Development of an oligonucleotide microarray for simultaneous detection of two canine MDR1 genotypes and association between genotypes and chemotherapy side effects

Lee JJ, Lin HY, Chen CA, Lin CS, Wang LC

Canine MDR1 gene mutations produce translated P-glycoprotein, an active drug efflux transporter, resulting in dysfunction or over-expression. The 4-base deletion at exon 4 of MDR1 at nucleotide position 230 (nt230[del4])...
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Identification, sequence analysis, and infectivity of H9N2 avian influenza viruses isolated from geese

Zhu R, Yang X, Zhang J, Xu D, Fan J, Shi H, Wang S, Liu X

The subtype H9N2 avian influenza virus greatly threatens the Chinese poultry industry, even with annual vaccination. Waterfowl can be asymptomatically infected with the H9N2 virus. In this study, three H9N2...
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Subclassification and Detection of New Markers for the Discrimination of Primary Liver Tumors by Gene Expression Analysis Using Oligonucleotide Arrays

Hass HG, Vogel U, Scheurlen , Jobst J

BACKGROUND/AIMS: The failure to correctly differentiate between intrahepatic cholangiocarcinoma (CC) and hepatocellular carcinoma (HCC) is a significant clinical problem, particularly in terms of the different treatment goals for both cancers....
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Sequencing analysis of HPV-other type on an HPV DNA chip

Kim MJ, Kim JJ, Kim S

OBJECTIVES: To identify the specific human papillomavirus (HPV) genotypes from HPV-other type on an HPV DNA chip test by sequencing. METHODS: Among 13,600 women undergoing a routine gynecology examination including Pap...
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Comparison of Four Human Papillomavirus Genotyping Methods: Next-generation Sequencing, INNO-LiPA, Electrochemical DNA Chip, and Nested-PCR

Nilyanimit P, Chansaenroj J, Poomipak W, Praianantathavorn K, Payungporn S, Poovorawan Y

BACKGROUND: Human papillomavirus (HPV) infection causes cervical cancer, thus necessitating early detection by screening. Rapid and accurate HPV genotyping is crucial both for the assessment of patients with HPV infection...
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Regulation of human gingival fibroblast gene expression on microgrooves: A DNA microarray study

Lee K, Leesungbok R, Ahn SJ, Park SJ, Lee SW

PURPOSE: We aimed to investigate the gene expression of human gingival fibroblasts on microgroove surface using DNA microarray. MATERIALS AND METHODS: Microgrooves were applied on grade II titanium discs to have...
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Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis

Nemati S, Fazaeli A, Hajjaran H, Khamesipour A, Anbaran MF, Bozorgomid A, Zarei F

Despite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the genetic characteristics of the causative agents. Applying both HSP70 PCR-RFLP and sequence...
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Sequence Analysis of Mitochondrial Genome of Toxascaris leonina from a South China Tiger

Li K, Yang F, Abdullahi , Song M, Shi X, Wang M, Fu Y, Pan W, Shan F, Chen W, Li G

Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from...
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Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors

Naqvi AA, Anjum F, Khan FI, Islam A, Ahmad F, Hassan MI

Helicobacter pylori is a Gram-negative bacteria that is responsible for gastritis in human. Its spiral flagellated body helps in locomotion and colonization in the host environment. It is capable of...
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Clinical Significance of an HPV DNA Chip Test with Emphasis on HPV-16 and/or HPV-18 Detection in Korean Gynecological Patients

Yeo MK, Lee A, Hur SY, Park JS

BACKGROUND: Human papillomavirus (HPV) is a major risk factor for cervical cancer. METHODS: We evaluated the clinical significance of the HPV DNA chip genotyping assay (MyHPV chip, Mygene Co.) compared with...
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Comparison of Analytical and Clinical Performance of HPV 9G DNA Chip, PANArray HPV Genotyping Chip, and Hybrid-Capture II Assay in Cervicovaginal Swabs

Jung HY, Han HS, Kim HB, Oh SY, Lee SJ, Kim WY

BACKGROUND: Human papillomavirus (HPV) infection can be detected by using several molecular methods, including Hybrid-Capture II (HC2) assay and variable HPV DNA chip tests, although each method has different sensitivities...
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The Application of DNA Chip Technology to Identify Herbal Medicines: an Example from the Family Umbelliferae

Kim PH, Park J, Kim YS, Suh Y

Comparative molecular analysis has been frequently adopted for the authentication of herbal medicines as well as the identification of botanical origins. Roots and rhizomes of the family Umbelliferae have been...
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In Silico Sequence Analysis Reveals New Characteristics of Fungal NADPH Oxidase Genes

Detry N, Choi J, Kuo HC, Asiegbu FO, Lee YH

NADPH oxidases (Noxes), transmembrane proteins found in most eukaryotic species, generate reactive oxygen species and are thereby involved in essential biological processes. However, the fact that genes encoding ferric reductases...
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Genetic Relationship in Bone Samples Using SNP-Based Human Identification DNA Chip

Cho S, Yu HJ, Han J, Lee HY, Lee J, Lee SD

DNA profiling with sets of short tandem repeat (STR) markers is the most popular method for identifying human DNA in forensics. Identification by STR typing might fail when DNA is...
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Differential Gene Expression in Placenta of Term Pregnant Women with and without Labor using cDNA Microarray

Kim A, Kim OK, Seo MW, Yang DE, Ahn HY, Park IY, Lee GS, Shin JC

  • KMID: 2280612
  • Korean J Perinatol.
  • 2007 Dec;18(4):370-377.
OBJECTIVE:cDNA microarray technology was used to comprehensively analyze the gene expression in the placenta of term women with labor compared to without labor. METHODS:Placental tissue was obtained from patients in spontaneous...
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Operational Experience of a Quality Assurance System for HPV DNA Chip Tests

Kang TH, Kahng J

  • KMID: 2005719
  • J Lab Med Qual Assur.
  • 2007 Dec;29(2):267-275.
BACKGROUND: A new HPV DNA chip test for the infection of 22 HPV genotypes was recently developed in Korea. This test using PCR and hybridization is inherently vulnerable to contamination,...
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A differential gene expression profiles by cDNA microarrays in endometrioid endometrial carcinoma: a preliminary study

Chung MJ, Chung EJ, Lee TH, Cho YL, Park IS, Lee YS

  • KMID: 2244551
  • Korean J Gynecol Oncol.
  • 2007 Sep;18(3):219-226.
OBJECTIVE: Endometrial carcinoma is the most common gynecological malignant disease in industrialized countries. However, the molecular bases for endometrial tumoriogenesis are not clearly elucidated. Our hypothesis is that there may...
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Pseudooutbreak of Acinetobacter spp. Bacteriuria Confirmed by 16S rRNA Gene Sequence Analysis

Kim SY, Kim JY, Kang JH, Park SY, Lee HS, Park YS, Seo YH, Cho YK

  • KMID: 1528885
  • Infect Chemother.
  • 2007 Aug;39(4):208-212.
BACKGROUND: Acinetobacter spp. is increasingly implicated in hospital-acquired infections. We experienced a pseudooutbreak of Bordetella bronchiseptica bacteriuria identified with biochemical tests, that was later identified as Acinetobacter spp. by using...
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Identification of Matrix Mineralization-Related Genes in Human Periodontal Ligament Cells Using cDNA Microarray

Shin JH, Park JW, Yeo SI, Noh WC, Kim MK, Kim JC, Suh JY

No abstract available.
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Identification of Interleukin 1-Responsive Genes in Human Chondrosarcoma SW1354 cells by cDNA Microarray Technology

Jeon JH, Jung YW, Yun DY, Kim HD, Kwon CM, Hong YH, Kim JR, Lee CK

  • KMID: 2320152
  • Yeungnam Univ J Med.
  • 2007 Jun;24(1):24-40.
BACKGROUND: Accumulating evidence shows that interleukin(IL)-1 plays a critical role in inflammation and connective tissue destruction observed in both osteoarthritis and rheumatoid arthritis. IL-1 induces gene expression related to cytokines,...
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