- P50 and Schizophrenia
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Lee SH, Seo HS, Chung YC
- KMID: 1511821
- Korean J Biol Psychiatry.
- 2006 Aug;13(3):137-143.
One of the most widely recognized neurophysiologic endophenotypes for schizophrenia is deficient gating or inhibition of the P50 component of the auditory event-related potential(ERP). A deficit in P50 sensory gating... -
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- Study on the P50 Auditory Evoked Potential in Mood Disorder Subjects
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Kim KJ, Lee NY, Ahn YM, Kang UK
- KMID: 2066597
- J Korean Neuropsychiatr Assoc.
- 2010 Sep;49(5):516-522.
OBJECTIVES: Diminished suppression of the P50 response, a consistent finding in schizophrenia, has also been reported in patients with bipolar disorder. It is a promising endophenotype for schizophrenia, but its... -
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- The Meaning of P50 Suppression: Interaction of Gamma and Alpha Waves
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Lee K, Kang UG
- KMID: 2299842
- Korean J Biol Psychiatry.
- 2014 Nov;21(4):168-174.
- doi: 10.0000/kjbp.2014.21.4.168
OBJECTIVES: Sensory gating dysfunctions in patients with schizophrenia and bipolar disorder have been investigated through two similar methods ; P50 suppression and prepulse inhibition paradigms. However, recent studies have demonstrated... -
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- A Computational Modeling Reveals That Strength of Inhibitory Input, E/I Balance, and Distance of Excitatory Input Modulate Thalamocortical Bursting Properties
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Park S, Sohn JW, Cho J, Huh Y
- KMID: 2463712
- Exp Neurobiol.
- 2019 Oct;28(5):568-577.
- doi: 10.5607/en.2019.28.5.568
The thalamus is a brain structure known to modulate sensory information before relaying to the cortex. The unique ability of a thalamocortical (TC) neuron to switch between the high frequency... -
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- Effects of 5HT1A Activation on Gating Profile Following 5HT Depletion in Rats Lacking Social Attachment Since Weanling
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Tai YM, Ko CY, Lin CC, Wan YY, Chung JY, Liu YP
- KMID: 2409429
- Psychiatry Investig.
- 2018 Feb;15(2):193-199.
- doi: 10.30773/pi.2017.05.14.2
OBJECTIVE: Central 5-HT1A receptor is involved in the modulation of sensorimotor gating function. However, its precise role is not clearly defined in developmentally social deprived (isolation rearing, IR) rats featured... -
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- Childhood Attention Deficit in the Patients with Bipolar Disorder and CHRNA7 Gene Polymorphisms
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Jeong SH, Kim EJ, Lee KY, Koo YJ, Song JY, Song HJ, Yi JE, Joo EJ
- KMID: 2287486
- Korean J Psychopharmacol.
- 2011 Oct;22(4):223-229.
OBJECTIVE: Patients with bipolar disorder have attention deficit during even euthymic status. Bipolar disorder patients showed more childhood attention deficit and other ADHD like feature. Alpha 7 nicotinic receptor (CHRNA7)... -
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- Prepulse Inhibition of Startle Response: Recent Advances in Human Studies of Psychiatric Disease
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Takahashi , Hashimoto , Iwase M, Ishii R, Kamio Y, Takeda M
- KMID: 2171253
- Clin Psychopharmacol Neurosci.
- 2011 Dec;9(3):102-110.
Prepulse inhibition (PPI) is considered to be one of the most promising neurophysiological indexes for translational research in psychiatry. Impairment of PPI has been reported in several psychiatric diseases, particularly... -
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