- Molecularly Targeted Therapy for Lung Cancer : Recent Topics
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Saijo N
- KMID: 2200065
- J Lung Cancer.
- 2008 Jun;7(1):1-8.
- doi: 10.6058/jlc.2008.7.1.1
Many clinical trials of molecular target drugs have been done against advanced lung cancer, however, majority did not meet the primary endpoint. Positive studies of EGFR-TKI such as BR21 and... -
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- The Role of Pharmacoethnicity in the Development of Cytotoxic and Molecular Targeted Drugs in Oncology
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Saijo N
- KMID: 1776911
- Yonsei Med J.
- 2013 Jan;54(1):1-14.
- doi: 10.3349/ymj.2013.54.1.1
The effective and toxic ranges of anticancer drugs are very narrow and, in some cases, inverted. Thus determination of the most appropriate dosage and schedule of administration is crucial for... -
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- Treatment of Small Cell Lung Cancer
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Horiike A, Saijo N
- KMID: 2166175
- Cancer Res Treat.
- 2003 Jun;35(3):177-180.
Among patients with lung cancer, approximately 15% have small cell lung cancer (SCLC), SCLC is usually staged as either limited and extensive. Extensive-stage SCLC is treated primarily with chemotherapy. A... -
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- Present Status and Problems on Molecular Targeted Therapy of Cancer
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Saijo N
- KMID: 2167581
- Cancer Res Treat.
- 2012 Mar;44(1):1-10.
Numerous clinical trials of molecular targeted drugs for cancer have been conducted, with remarkable results for certain drugs and accumulation of "negative data" causing a hitch in the development plan... -
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- Antitumor Activity of Oxaliplatin, 5-FU and Paclitaxel Given Alone or in Combination with ZD1839 in Human Gastric Carcinoma Cells in vitro
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Jang JH, Lee SH, Kang JH, Sun HS, Nishio K, Saijo N, Kuh HJ
- KMID: 1972943
- Cancer Res Treat.
- 2002 Oct;34(5):372-381.
PURPOSE: Oxaliplatin (LOHP), 5-FU, and paclitaxel (PTX) are considered highly active against advanced gastric carcinomas, and the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, ZD1839 is considered as a... -
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