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Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy

Kalanxhi E, Risberg K, Barua IS, Dueland S, Waagene S, Andersen S, Pettersen , Lindvall J, Redalen KR, Flatmark K, Ree AH

PURPOSE: When integrating molecularly targeted compounds in radiotherapy, synergistic effects of the systemic agent and radiation may extend the limits of patient tolerance, increasing the demand for understanding the pathophysiological...
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