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Are You Being Rejected or Excluded? Insights from Neuroimaging Studies Using Different Rejection Paradigms

Premkumar

Rejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim...
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The Role of Macrophages in Transplant Rejection

Yeom HJ, Ahn C, Yang J

Macrophage accumulation has been recognized as a feature of allograft rejection, however, the role of macrophages in rejection remains underappreciated. Macrophages are present within graft tissues throughout the lifespan of...
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The Diagnosis of Acute Antibody-Mediated Rejection in ABO-Incompatible Liver Transplants

Kwon GY

Liver transplantation (LT) across the ABO-blood type barrier is prone to antibody-mediated rejection (AMR), which often leads to a deleterious clinical outcome. While it is of paramount importance to make...
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Efficacy of Amniotic Membrane Transplantation on Corneal Graft Rejection with Epithelial Defects after Penetrating Keratoplasty

Kang IS, Kim YH, Song TB, Cho JK, Park YG, Yoon KC

We report the therapeutic effect of amniotic membrane transplantation (AMT) on corneal graft rejection with epithelial defects after penetrating keratoplasty (PKP). Twelve patients (12 eyes) who had epithelial and subepithelial...
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Strategies to Overcome Memory T Cells Mediatied Allograft Injury

Kim BS

  • KMID: 2324212
  • J Korean Soc Transplant.
  • 2012 Jun;26(2):69-73.
During the last few decades our knowledge of transplantation has been remarkably expanded to the point where transplants are a standard treatment modality. However, despite the fact that certain tolerogenic...
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Pathologic Updates on Antibody Mediated Rejection in Renal Transplantation

Choi YJ

  • KMID: 2324076
  • J Korean Soc Transplant.
  • 2013 Jun;27(2):42-48.
Progress in the field of antibody mediated rejection (ABMR) in kidney transplantation has shown a rapid increase during the past two decades. New pathologic entities have emerged and replace old...
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The Impact of ABCB1 Gene Polymorphism on Steroid Responsiveness in Acute Rejection in Kidney Transplantation

Ro H, Min SI, Jeong JC, Koo TY, Yang J, Ha J, Ahn C

BACKGROUND: Steroid pulse therapy has been used for patients with acute rejection after kidney transplantation. The ABCB1 gene codes for P-glycoprotein, a transporter that is involved in the metabolism of...
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Steroid Withdrawal in Renal Transplantation

Kim JK

  • KMID: 2324403
  • J Korean Soc Transplant.
  • 2008 Dec;22(2):197-202.
Steroid is a critical component of immunosuppressive regimen. Unfortunately, steroid is associated with numerous adverse effects including diabetes, hypertension, hyperlipidemia, osteoporosis, sodium retention, and avascular necrosis. These adverse effects have...
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Immunologic monitoring in kidney transplant recipients

Townamchai N, Safa K, Chandraker A

  • KMID: 2093108
  • Kidney Res Clin Pract.
  • 2013 Jun;32(2):52-61.
Transplant biopsy has always been the gold standard for assessing the immune response to a kidney allograft (Chandraker A: Diagnostic techniques in the work-up of renal allograft dysfunction-an update. Curr...
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Update on the Treatment of Acute and Chronic Antibody-mediated Rejection

Park KT, Jung CW, Kim MG

Antibody-mediated rejection (AMR) by preformed and/or de novo human leukocyte antigen alloantibodies is a leading cause of early and late allograft loss. In this review, we describe strategic approaches to...
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Allograft Immune Reaction of Kidney Transplantation: Part 1. Mechanism of Allograft Rejection

Kang HG

  • KMID: 2322082
  • J Korean Soc Pediatr Nephrol.
  • 2008 Apr;12(1):23-29.
Kidney allograft transplantation is the most effective method of renal replacement for end stage renal disease patients. Still, it is another kind of 'disease', requiring immunosuppression to keep the allograft...
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Intravenous Immunoglobulin Treatment in a Kidney Transplant Patient with Chronic Antibody-Mediated Rejection

Byun SW, Yeo Y, Park JS, Cho YM, Park SK

  • KMID: 2080013
  • Korean J Nephrol.
  • 2009 Jul;28(4):375-380.
A 66-year-old male was admitted for increasing azotemia. He was diagnosed with chronic antibody- mediated rejection and had received a livingdonor renal transplant from his 32-year-old son prior to his...
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The Relationship between Recipients Age on the Development of Acute Rejection and Graft Survival in Kidney Transplantation

Han SS, Lee SW, Ahn JM, Ahn C, Han JS, Kim S, Kim YS

  • KMID: 1477248
  • Korean J Nephrol.
  • 2008 Sep;27(5):576-583.
PURPOSE: Previously, acute rejection (AR) episode in the elderly recipients was reported to be lower compared to that of young recipients. However, the relationship between the recipients age, incidence of...
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Treatment of Posttransplantation Recurrent Glomerulonephritis: IgA Nephropathy, Membranous Nephropathy, Membranoproliferative Glomerulonephritis

Chung HC, Park J, Lee JS

  • KMID: 2324200
  • J Korean Soc Transplant.
  • 2011 Jun;25(2):81-86.
As the clinical outcomes improve in kidney transplantation, largely because of the prevention of loss due to acute rejection, the incidence of allograft loss due to recurrent glomerulonephritis have become...
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Predictive Value of Donor Specific Antibody Measured by Luminex Single Antigen Assay for Antibody Mediated Rejection after Kidney Transplantation

Joo DJ, Huh KH, Kim YS, Yoon SJ, Kim HJ, Sohn SS, Kim HJ, Kim SI, Kim HS, Kim MS

BACKGROUND: Luminex panel reactive antibody (PRA) is a method that is well known for its high sensitivity and specificity. By using a single antigen assay, the presence or absence of...
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The Significance and Limitation of C4d as a Biomarker in the Transplanted Kidney

Han JY

C4d is produced from the direct interaction between antibodies and tissue injury at an antibody binding site in a graft. C4d deposition along peritubular capillaries (PTCs) in a renal allograft...
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Psychiatric Approach in the Treatment of Obesity

Kang WS, Kim JW

  • KMID: 1992477
  • Korean J Obes.
  • 2010 Sep;19(3):71-77.
There are some evidence to suggest that common mental disorders and obesity may be related to one another. Co-occurrence between psychiatric disorders and obesity should be taken into account during...
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The Risk Factors of Acute Cellular Rejection in Adult Living Donor Liver Transplantation:Doubting the Value of Positive Lymphocytotoxic Cross-match Results

Jung KU, Park JB, Kim JM, Moon JI, Jung GO, Chun JM, Choi GS, Kwon CD, Kim SJ, Joh JW, Lee SK

BACKGROUND: The influence of lymphocytotoxic cross-match results on acute cellular rejection in adult living donor liver transplantation (LDLT) has not been well examined. Therefore, in this study, we investigated the...
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Current status of pediatric kidney transplantation

Kim SD, Cho BS

Renal transplantation is the treatment of choice for children with end-stage renal disease. The outcome of pediatric kidney transplantation has improved dramatically in recent years, with lower acute rejection rates,...
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Common Infections in Solid Organ Transplant Recipients

Lee SO

  • KMID: 2267872
  • Korean J Med.
  • 2013 Feb;84(2):145-157.
Improved immunosuppressive therapies for solid organ transplantation (SOT) have reduced the incidence of allograft rejection while increasing susceptibility to opportunistic infections. Diagnosis and treatment for infectious disease after SOT are...
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